Acetyl CoA and choline, combined under the influence of choline acetyltransferase.
A postsynaptic depolarization caused by ion exchange after ACh binds to nicotinic receptors.
A synapse between motor neurons and skeletal muscle that converts neuronal impulses into muscle contractions.
Acetylcholine (ACh).
In the presynaptic terminal of the motor neuron.
Calcium influx resulting from the opening of voltage-gated calcium channels after an action potential depolarizes the presynaptic terminal.
The receptors undergo a conformational change, opening Na+/K+ ion channels, leading to postsynaptic depolarization.
Small depolarizations that can summate to generate a stronger endplate potential (EPP).
The EPP generates an action potential that spreads to adjacent muscle fibers, resulting in muscle contraction.
It breaks down ACh into acetate and choline, facilitating the cessation of the neuromuscular signal.
It is taken up by the presynaptic terminal for new acetylcholine synthesis.
