What is the third step in the allergic cascade?
Late-phase response to an allergen.
What are the two main classifications of adverse reactions to food?
Toxic and Non-toxic (host specific).
1/274
p.31
Immune System Response to Allergens

What is the third step in the allergic cascade?

Late-phase response to an allergen.

p.4
Definition and Classification of Food Allergies

What are the two main classifications of adverse reactions to food?

Toxic and Non-toxic (host specific).

p.44
Management and Treatment of Food Allergies

Where is epinephrine produced in the body?

By the adrenal gland.

p.22
Immune System Response to Allergens

What causes allergies?

Hypersensitivity of the immune system to environmental substances.

p.49
Diagnosis of Food Allergies

What do many insurers consider allergies or asthma related to allergies?

A pre-existing condition.

p.19
Immune System Response to Allergens

What is the primary function of the immune system?

To protect the body from potentially harmful foreign molecules.

p.12
Natural History and Risk Factors of Food Allergies

What can infant-onset food allergies trigger later in life?

Other allergic diseases.

p.12
Natural History and Risk Factors of Food Allergies

What is the typical evolution of allergic disease associated with asthma?

It often includes asthma and allergic rhinitis.

p.49
Management and Treatment of Food Allergies

How much does a single consultation with an allergist cost in Hong Kong?

Around HKD 1,600, excluding medications.

p.39
Diagnosis of Food Allergies

Which test measures specific antibodies in the blood to diagnose food allergies?

Blood Test.

p.43
Management and Treatment of Food Allergies

What is the primary strategy for managing food allergies?

Avoid the allergen-containing food(s).

p.44
Management and Treatment of Food Allergies

What is epinephrine also known as?

Adrenaline.

p.19
Immune System Response to Allergens

What percentage of immune activity occurs in the intestinal tract?

Over 60%.

p.10
Prevalence of Food Allergies Worldwide

What percentage of children in Hong Kong are affected by food allergies?

5 - 8%.

p.19
Immune System Response to Allergens

Why is the intestinal tract significant for the immune system?

Because the majority of potentially harmful molecules enter the body through it.

p.44
Immune System Response to Allergens

When is epinephrine produced?

During the 'flight-or-fight' response.

p.10
Prevalence of Food Allergies Worldwide

What percentage of children aged 2 - 7 in Hong Kong have shown adverse effects from food?

8.1%.

p.46
Management and Treatment of Food Allergies

What is the primary use of steroids in the context of the immune system?

To calm down the immune system cells.

p.40
Diagnosis of Food Allergies

What is the purpose of the Skin Prick Test?

To identify allergic reactions to specific allergens.

p.35
Immune System Response to Allergens

How long can the late-phase response last?

It can last for about 24 hours before subsiding.

p.46
Anaphylaxis and Emergency Response

Should steroids be used to treat anaphylaxis?

No, they should not be used for anaphylaxis.

p.42
Diagnosis of Food Allergies

What type of allergies can be detected through double-blind placebo-controlled food challenges?

Non-IgE mediated allergies.

p.16
Common Allergenic Foods

What are some examples of foods that can cause allergies in the meat category?

Beef, lamb, and pork.

p.20
Immune System Response to Allergens

What is the role of macrophage cells in the immune system?

They act as 'scavenger' cells, removing and destroying damaging molecules.

p.27
Symptoms and Severity of Allergic Reactions

What is a typical cutaneous symptom of IgE-mediated reactions?

Urticaria.

p.37
Symptoms and Severity of Allergic Reactions

What skin condition is associated with Celiac Disease?

Dermatitis herpetiformis.

p.3
Immune System Response to Allergens

What is the first step in the allergic cascade?

Sensitization.

p.46
Management and Treatment of Food Allergies

How can steroids be administered?

Orally or through injection.

p.22
Immune System Response to Allergens

What are mast cells?

Tissue cells of the immune system that cause allergic symptoms.

p.16
Common Allergenic Foods

What type of spicy food can cause allergic reactions?

Hot peppers.

p.27
Symptoms and Severity of Allergic Reactions

What is atopic dermatitis?

A cutaneous symptom associated with IgE-mediated reactions.

p.6
Prevalence of Food Allergies Worldwide

What organization conducted the food allergy perception survey in 2007?

IFIC Foundation.

p.39
Diagnosis of Food Allergies

What is a common screening tool for diagnosing food allergies?

Skin Prick Test.

p.14
Prevalence of Food Allergies Worldwide

Is the prevalence of food allergies higher in boys or girls in Hong Kong?

Slightly more among boys.

p.19
Immune System Response to Allergens

Where is the immune system most active in the body?

In areas with direct contact with the outside world, such as the skin, lungs, nose, and gastrointestinal tract.

p.47
Prevention Strategies for Food Allergies

What are the three levels of allergy prevention according to the World Allergy Organization?

Primary, Secondary, and Tertiary Prevention.

p.12
Natural History and Risk Factors of Food Allergies

What is the typical evolution of allergic disease without asthma?

It may occur without asthma and allergic rhinitis.

p.45
Management and Treatment of Food Allergies

What is the function of antihistamines?

They block the action of histamine.

p.33
Immune System Response to Allergens

What happens during the sensitization phase of an allergic reaction?

The body produces IgE antibodies specific to an allergen without experiencing a reaction.

p.7
Prevalence of Food Allergies Worldwide

What is the prevalence of food allergies in Germany?

2 - 3%.

p.35
Immune System Response to Allergens

Which immune cells are primarily involved in the late-phase response?

Eosinophils.

p.8
Prevalence of Food Allergies Worldwide

How many people are affected by asthma globally?

300 million.

p.15
Common Allergenic Foods

What percentage of all food allergies do the 'Big 8' allergens account for?

More than 90%.

p.3
Definition and Classification of Food Allergies

What is the definition of food allergy?

An abnormal immune response to specific food proteins.

p.43
Anaphylaxis and Emergency Response

What emergency therapy is recommended for food allergies?

Epinephrine (adrenaline) shot.

p.37
Symptoms and Severity of Allergic Reactions

What are common gastrointestinal symptoms of Celiac Disease?

Mouth sores, abdominal bloating and pain, diarrhea, and steatorrhea.

p.30
Prevalence of Food Allergies Worldwide

What trend was observed in the incidence of food-induced anaphylaxis between 2009 and 2019?

There was more than a twofold increase in incidence.

p.10
Prevalence of Food Allergies Worldwide

What is the issue with allergy specialists in Hong Kong?

The ratio of allergy specialists per population is quite low.

p.21
Immune System Response to Allergens

What do B-cells produce?

Antibodies.

p.9
Prevalence of Food Allergies Worldwide

What percentage of children under 3 years of age have food allergies?

6%.

p.6
Prevalence of Food Allergies Worldwide

What percentage of the entire US population do people think have food allergies according to the survey?

25%.

p.6
Prevalence of Food Allergies Worldwide

How many participants were involved in the food allergy perception survey in the US?

1000 participants.

p.49
Management and Treatment of Food Allergies

Are allergy tests and treatments expensive in Hong Kong?

Yes, they are very expensive.

p.29
Anaphylaxis and Emergency Response

How many emergency room visits are estimated per year due to food-induced anaphylaxis in the US?

50,000.

p.49
Diagnosis of Food Allergies

What is a potential consequence of having allergies classified as a pre-existing condition by insurers?

You may not be eligible for coverage.

p.31
Immune System Response to Allergens

What occurs following exposure to an allergen?

A series of reactions in the immune system.

p.29
Anaphylaxis and Emergency Response

What is the estimated number of deaths per year due to food-induced anaphylaxis in the US?

150 - 200.

p.45
Immune System Response to Allergens

What is histamine?

One of the major mediators that causes blood vessels to dilate and become leaky to plasma proteins.

p.28
Anaphylaxis and Emergency Response

What is anaphylactic shock?

A generalized shock reaction that can lead to multiple organ failure.

p.29
Anaphylaxis and Emergency Response

Is food-induced anaphylaxis considered rare?

No, it is not rare.

p.31
Immune System Response to Allergens

What is the first step in the allergic cascade?

Sensitization to an allergen.

p.8
Prevalence of Food Allergies Worldwide

What percentage of school-aged children are affected by one or more forms of allergy?

40 - 50%.

p.45
Immune System Response to Allergens

What effect does histamine have on sensory nerve terminals?

It causes itchiness.

p.14
Prevalence of Food Allergies Worldwide

How does the prevalence of food allergies vary among different age groups in Hong Kong?

It is similar among different age bands (infant, toddler, preschooler, primary school children, early secondary school children).

p.28
Anaphylaxis and Emergency Response

What are the severe symptoms of anaphylactic shock?

Severe loss of blood pressure and cardiac arrhythmia.

p.39
Diagnosis of Food Allergies

What is a food challenge in the context of food allergy diagnosis?

A test where the patient consumes the suspected allergen under medical supervision.

p.31
Immune System Response to Allergens

What is the second step in the allergic cascade?

Early-phase response upon re-exposure to an allergen.

p.8
Prevalence of Food Allergies Worldwide

How many children had food allergies in 2012?

4.1 million.

p.43
Management and Treatment of Food Allergies

What can trigger allergic reactions in sensitive individuals?

Trace amounts (ppm concentrations) of the offending food.

p.28
Anaphylaxis and Emergency Response

What can happen if anaphylactic shock is not treated immediately?

It can be fatal.

p.14
Prevalence of Food Allergies Worldwide

What percentage of food allergies in Hong Kong are single item allergies?

85%.

p.11
Natural History and Risk Factors of Food Allergies

What is the likelihood of infants outgrowing their food allergies?

Most infants outgrow their allergy within months, especially if it occurs before 3 years of age.

p.7
Prevalence of Food Allergies Worldwide

What is the prevalence of food allergies in Australia?

1 - 2% of the population.

p.35
Immune System Response to Allergens

What is the late-phase response in allergic reactions?

A secondary immune response that begins at the same time as the early-phase response but takes longer to manifest.

p.8
Prevalence of Food Allergies Worldwide

How many children had skin allergies in 2012?

8.8 million.

p.43
Management and Treatment of Food Allergies

What is a Food Allergy Action Plan?

A plan that includes informing family, friends, and caretakers about the allergy.

p.12
Natural History and Risk Factors of Food Allergies

What is the risk for infants with eczema regarding asthma and allergic rhinitis?

They have a higher risk of developing asthma and allergic rhinitis.

p.18
Definition and Classification of Food Allergies

What are the primary causative agents of food allergies?

Naturally-occurring proteins.

p.26
Immune System Response to Allergens

What type of allergy is characterized by a chronic inflammatory response?

IgE mediated allergy.

p.21
Immune System Response to Allergens

What role do T-cells play in the immune system?

They conduct surveillance for potentially dangerous molecules and kill dangerous cells such as disease-causing bacteria.

p.7
Prevalence of Food Allergies Worldwide

What is the prevalence of food allergies in The Netherlands?

5%.

p.18
Definition and Classification of Food Allergies

What type of proteins are usually responsible for food allergies?

Major proteins of the food.

p.5
Symptoms and Severity of Allergic Reactions

How quickly do food allergy symptoms typically occur after exposure?

Within minutes to several hours.

p.15
Common Allergenic Foods

What should be considered when using oils in relation to allergens?

Proceed with caution; highly refined oils largely remove protein, but cold-pressed oils may contain allergenic proteins.

p.48
Prevention Strategies for Food Allergies

When was the Hong Kong Institute of Allergy founded?

In 1996.

p.36
Immune System Response to Allergens

What type of allergic response is characterized by T-cells and macrophages?

Non IgE mediated Cell-Mediated Allergic Response.

p.32
Immune System Response to Allergens

What are examples of allergens that can be inhaled?

Pollen, mold, dust mites.

p.30
Prevalence of Food Allergies Worldwide

How many times were patients admitted for anaphylaxis during the 11-year span?

2,961 times.

p.33
Immune System Response to Allergens

What are mast cells compared to in the context of sensitization?

Little bombs that are armed and ready for explosion.

p.4
Common Allergenic Foods

What condition is associated with gluten intolerance?

Celiac disease.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to peanuts?

5%.

p.2
Symptoms and Severity of Allergic Reactions

How long does it usually take for symptoms of an allergic reaction to appear?

It can take several days.

p.24
Immune System Response to Allergens

What type of allergy is characterized by an IgE mediated response?

IgE mediated allergy.

p.36
Definition and Classification of Food Allergies

What is an example of a non IgE mediated allergic response?

Celiac Disease.

p.2
Diagnosis of Food Allergies

Does a positive skin prick test guarantee a reaction to that food when eaten?

No, it does not guarantee a reaction.

p.1
Management and Treatment of Food Allergies

What are some management strategies for food allergies?

Avoidance of allergens, carrying emergency medication, and education.

p.2
Symptoms and Severity of Allergic Reactions

Will reactions always become increasingly severe each time you have one?

No, reactions do not always become increasingly severe.

p.41
Diagnosis of Food Allergies

Can non-IgE mediated allergies be detected by the RAST test?

No, they cannot be detected.

p.13
Natural History and Risk Factors of Food Allergies

What is the risk of allergy in infants fed with intact cow's milk protein after the first week of life?

20-30%.

p.13
Natural History and Risk Factors of Food Allergies

What is the highest reported risk of allergy in infants?

50-60%.

p.17
Common Allergenic Foods

What is an example of a food related to cow's milk that may cause allergic reactions?

Beef (hamburger).

p.11
Natural History and Risk Factors of Food Allergies

Which food allergies are most commonly outgrown within the first ten years of life?

Allergies to milk, eggs, soy, and wheat.

p.7
Prevalence of Food Allergies Worldwide

What percentage of the Canadian population has food allergies?

1 - 2%.

p.11
Natural History and Risk Factors of Food Allergies

What percentage of individuals outgrow peanut allergies?

Only 20%.

p.8
Prevalence of Food Allergies Worldwide

How many people are affected by allergic rhinitis globally?

400 million.

p.47
Prevention Strategies for Food Allergies

What does Secondary Prevention involve?

Staying away from known allergens.

p.4
Definition and Classification of Food Allergies

What type of adverse reaction is a food allergy classified as?

Immune mediated.

p.44
Management and Treatment of Food Allergies

What effect does epinephrine have on allergic reactions?

It reverses the allergic reaction by improving blood circulation.

p.34
Immune System Response to Allergens

What are the substances released by mast cells during an allergic response?

Histamine and other inflammatory mediators.

p.25
Immune System Response to Allergens

What type of allergy is associated with a late phase response?

IgE mediated allergy.

p.9
Prevalence of Food Allergies Worldwide

What is the prevalence of food allergies among adults in the US?

3.7%.

p.35
Symptoms and Severity of Allergic Reactions

What symptoms can be more severe during the late-phase response compared to the initial response?

Congestion and certain other symptoms.

p.33
Immune System Response to Allergens

Where do IgE antibodies bind after being produced?

To special receptors on mast cells.

p.4
Immune System Response to Allergens

What is the role of Immunoglobulin E (IgE) in food allergies?

It is involved in IgE-mediated reactions.

p.38
Prevalence of Food Allergies Worldwide

What is the prevalence of celiac disease in the U.S.?

3.5 million people.

p.25
Immune System Response to Allergens

Which cytokine is involved in the late phase response?

Tumor Necrosis Factor - α (TNF - α).

p.2
Prevalence of Food Allergies Worldwide

Are food allergies common globally?

Yes.

p.3
Immune System Response to Allergens

What occurs during the early-phase of an allergic reaction?

Immediate release of mediators from mast cells and basophils.

p.32
Immune System Response to Allergens

What does ingestion of an allergen refer to?

Swallowing a type of food or medication.

p.48
Prevention Strategies for Food Allergies

What is the main goal of the Hong Kong Institute of Allergy?

To share the most up-to-date knowledge on the management of allergic diseases.

p.1
Symptoms and Severity of Allergic Reactions

What are common symptoms of food allergies?

Symptoms can include hives, swelling, abdominal pain, and anaphylaxis.

p.40
Diagnosis of Food Allergies

What type of allergies cannot be detected by the Skin Prick Test?

Non-IgE mediated allergies.

p.3
Diagnosis of Food Allergies

What is involved in the diagnosis of a food allergy?

Clinical history, skin tests, and specific IgE tests.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to tree nuts?

37%.

p.1
Prevalence of Food Allergies Worldwide

What is the prevalence of food allergies worldwide?

Food allergies affect millions of people globally, with varying rates by region.

p.48
Prevention Strategies for Food Allergies

What is the main focus of the Hong Kong Allergy Association?

To raise public awareness of allergy through education and provide support to those with allergies.

p.24
Symptoms and Severity of Allergic Reactions

What are the effects of smooth muscle contraction in an allergic response?

It can lead to symptoms like dyspnea.

p.24
Immune System Response to Allergens

What role does histamine play in allergic reactions?

Histamine causes symptoms such as itchiness and rhinorrhea.

p.38
Immune System Response to Allergens

How does gluten affect the small intestine in celiac disease?

It damages the villi, making it difficult to absorb nutrients.

p.23
Symptoms and Severity of Allergic Reactions

What are the effects of IgE mediated allergies?

Acute effect, late-phase effect, and chronic effect.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to grains?

20%.

p.47
Prevention Strategies for Food Allergies

What is an example of Primary Prevention for allergies?

Breastfeeding and avoiding second-hand smoke and air pollutants.

p.34
Immune System Response to Allergens

What happens during the early-phase response upon re-exposure to an allergen?

IgE of mast cells binds to the allergen, leading to cross-linking.

p.28
Anaphylaxis and Emergency Response

What is the primary treatment for anaphylactic shock?

Epinephrine.

p.43
Management and Treatment of Food Allergies

What is important for early detection of allergic reactions?

Early symptom recognition.

p.11
Natural History and Risk Factors of Food Allergies

Which food allergies are often lifelong?

Peanut, tree nut, fish, and shellfish allergies.

p.22
Immune System Response to Allergens

What type of antibodies are involved in allergic reactions?

Immunoglobulin E (IgE) antibodies.

p.47
Prevention Strategies for Food Allergies

What is the focus of Tertiary Prevention?

Treatment and medication to reduce the risk of allergy.

p.10
Prevalence of Food Allergies Worldwide

What percentage of children with food allergies in Hong Kong have seen a doctor for a diagnosis?

4.6%.

p.22
Immune System Response to Allergens

What do IgE antibodies bind to in the allergic response?

An allergen and then to a receptor on mast cells.

p.44
Management and Treatment of Food Allergies

What is an EpiPen?

A self-injectable device for administering epinephrine.

p.43
Management and Treatment of Food Allergies

What can help identify individuals with food allergies in emergencies?

Medical identification necklaces or bracelets.

p.32
Immune System Response to Allergens

How can a person be initially exposed to an allergen?

Through inhalation, ingestion, touch, or injection.

p.7
Prevalence of Food Allergies Worldwide

What percentage of the population in Italy has food allergies?

6 - 8%.

p.34
Symptoms and Severity of Allergic Reactions

How quickly do symptoms of an allergic response occur after re-exposure?

Within an hour after initial exposure.

p.33
Natural History and Risk Factors of Food Allergies

What does it mean to be atopic?

Having an inherited sensitivity toward allergic disease.

p.4
Common Allergenic Foods

What are examples of foods that can cause allergies?

Peanut, Mushroom, and Lactose.

p.48
Prevention Strategies for Food Allergies

Who organized the Hong Kong Institute of Allergy?

A group of Allergists, Respirologists, Paediatricians, and Dermatologists.

p.2
Symptoms and Severity of Allergic Reactions

Are food allergies dangerous?

No, food allergies can be dangerous.

p.26
Immune System Response to Allergens

What are some chronic structural changes caused by allergic inflammation?

Muscle hypertrophy and organ dysfunction.

p.30
Management and Treatment of Food Allergies

Which group of patients was significantly less likely to have prescriptions for adrenaline auto-injectors?

Adult patients.

p.38
Diagnosis of Food Allergies

What percentage of people with celiac disease are undiagnosed or misdiagnosed?

>80%.

p.23
Immune System Response to Allergens

What cells contain mediators in IgE mediated allergies?

Mast cells.

p.27
Symptoms and Severity of Allergic Reactions

What gastrointestinal symptoms can occur in IgE-mediated reactions?

Swelling of the lips, nausea, vomiting, abdominal pain, and diarrhea.

p.40
Diagnosis of Food Allergies

Where can skin testing be performed?

On the arm or back.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to fish?

50%.

p.17
Common Allergenic Foods

What are examples of other fish that may cause allergic reactions?

Swordfish, sole.

p.23
Immune System Response to Allergens

What are some examples of mediators released during mast cell activation?

Histamine and TNF-α.

p.38
Natural History and Risk Factors of Food Allergies

What are some conditions that celiac disease can lead to?

Infertility, neurological disorders, some cancers, and other autoimmune diseases.

p.41
Diagnosis of Food Allergies

What happens if the patient's serum contains IgE antibodies?

Those antibodies will bind to the allergen.

p.17
Common Allergenic Foods

What are examples of other grains that may cause allergic reactions?

Barley, rye.

p.35
Immune System Response to Allergens

How long after the initial allergic reaction can the late-phase response occur?

Anywhere from about three to 10 hours later.

p.42
Diagnosis of Food Allergies

What type of food challenge is conducted in a hospital environment?

Double-blind placebo-controlled food challenges.

p.45
Anaphylaxis and Emergency Response

Do antihistamines completely improve dangerous symptoms in anaphylaxis?

No, they do not completely improve the dangerous symptoms that affect breathing.

p.5
Definition and Classification of Food Allergies

What is a food allergy?

An abnormal immune response to food.

p.7
Prevalence of Food Allergies Worldwide

What percentage of the United States population has food allergies?

4%.

p.20
Immune System Response to Allergens

What happens when an antibody binds to an antigen?

It identifies the molecule as potentially damaging and signals for its removal.

p.33
Immune System Response to Allergens

What do B cells produce in response to allergen sensitization?

IgE antibodies targeted to the specific allergen.

p.15
Common Allergenic Foods

Can the 'Big 8' allergens be consumed raw or cooked?

Yes, they can be raw or cooked.

p.3
Immune System Response to Allergens

What are the two main types of immune responses in food allergies?

IgE mediated allergy and Non IgE mediated allergy.

p.46
Management and Treatment of Food Allergies

What is a limitation of using steroids for treating allergic reactions?

They only relieve symptoms in the contact area and take a long time to work.

p.22
Immune System Response to Allergens

What do mast cells release that causes allergic symptoms?

Inflammatory chemicals such as histamine.

p.16
Common Allergenic Foods

Which vegetable is mentioned as a potential allergen?

Garlic.

p.10
Prevalence of Food Allergies Worldwide

Where do many patients in Hong Kong go for allergy-related treatments?

To their general practitioners.

p.42
Diagnosis of Food Allergies

Which publication discusses the reaction pattern in food challenges?

Bindslev-Jensen C, BMJ 1998;316:1299.

p.40
Diagnosis of Food Allergies

What serves as a positive control in the Skin Prick Test?

Proven allergens like histamine.

p.36
Immune System Response to Allergens

How is the pathogenesis of non IgE mediated allergic responses defined?

It is not as clearly defined as for IgE mediated allergic responses.

p.37
Symptoms and Severity of Allergic Reactions

What risk is associated with asymptomatic Celiac Disease?

Increased risk for malnutrition-related symptoms and complications.

p.40
Diagnosis of Food Allergies

What indicates an allergic reaction during the Skin Prick Test?

A hive forming at the injection site.

p.32
Immune System Response to Allergens

What is an example of an allergen that can be encountered through touch?

Poison ivy, latex, or certain metals like nickel.

p.48
Prevention Strategies for Food Allergies

When was the Hong Kong Allergy Association founded?

In 2008.

p.25
Immune System Response to Allergens

What are the two scenarios mentioned for the injection of an antigen?

Injection into the epidermis and response to an inhaled antigen.

p.24
Symptoms and Severity of Allergic Reactions

What is a key feature of the acute response in IgE mediated allergies?

It occurs within minutes to 2 hours.

p.23
Immune System Response to Allergens

What are the two stages of IgE mediated allergy?

Sensitization and Mast cell activation.

p.27
Symptoms and Severity of Allergic Reactions

What is anaphylactic shock?

A systemic symptom of IgE-mediated reactions that can be life-threatening.

p.36
Symptoms and Severity of Allergic Reactions

What type of disorder is Celiac Disease?

A chronic inflammatory disorder of the small intestine.

p.24
Symptoms and Severity of Allergic Reactions

What are some common symptoms of an IgE mediated allergy?

Symptoms include rhinorrhea, itchiness, dyspnea, itchy rash, throat swelling, and low blood pressure.

p.17
Common Allergenic Foods

What are examples of other shellfish that may cause allergic reactions?

Crab, lobster.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to cow's milk?

10%.

p.15
Common Allergenic Foods

What are the 'Big 8' food allergens?

Milk, Eggs, Peanuts, Tree nuts, Soy, Wheat, Fish, Crustacean shellfish.

p.20
Immune System Response to Allergens

What are antibodies?

Long, branched molecules that recognize and bind to specific antigens.

p.33
Immune System Response to Allergens

What role do T cells play in sensitization to allergens?

T cells stimulate B cells to produce IgE antibodies.

p.42
Diagnosis of Food Allergies

Who is present during a double-blind placebo-controlled food challenge?

A doctor.

p.16
Common Allergenic Foods

Which fruits are known to cause allergic reactions?

Mango and strawberries.

p.8
Prevalence of Food Allergies Worldwide

What does the WHO estimate about asthma prevalence by 2025?

400 million people will suffer from asthma.

p.32
Immune System Response to Allergens

What is the first step in the allergic cascade?

Sensitization to an allergen.

p.40
Diagnosis of Food Allergies

What is injected during an intradermal skin test?

A small amount of allergen just beneath the skin surface.

p.26
Immune System Response to Allergens

What can repeated allergen exposure lead to?

A chronic inflammatory response.

p.25
Immune System Response to Allergens

When does the late phase response occur after the original reaction?

2 to 24 hours.

p.40
Diagnosis of Food Allergies

What is used as a negative control in the Skin Prick Test?

Saline.

p.20
Immune System Response to Allergens

Can an antibody bind to multiple antigens?

No, an antibody will only bind to one specific antigen.

p.21
Immune System Response to Allergens

What is the function of macrophages in the immune system?

They act as scavenger cells to clean up residue and remove potentially dangerous substances.

p.15
Common Allergenic Foods

Is processing and preparation information always available for allergenic foods?

No, it is not always available.

p.20
Immune System Response to Allergens

What do macrophages do after an antibody binds to a dangerous molecule?

They consume the molecule, taking it out of circulation and destroying it.

p.5
Symptoms and Severity of Allergic Reactions

What can happen during a severe food allergy reaction?

Symptoms may include trouble breathing and low blood pressure.

p.30
Management and Treatment of Food Allergies

What percentage of anaphylaxis survivors were prescribed adrenaline auto-injectors (AAI)?

Fewer than 15%.

p.36
Immune System Response to Allergens

What are the primary cells involved in non IgE mediated allergic responses?

T-cells, macrophages, and other cells.

p.32
Immune System Response to Allergens

How can allergens be introduced through injection?

By receiving a medication or being stung by an insect.

p.36
Symptoms and Severity of Allergic Reactions

What areas of the body are affected by non IgE mediated allergic responses?

The gastrointestinal tract and skin.

p.38
Management and Treatment of Food Allergies

What is the only treatment for celiac disease?

A strict gluten-free diet.

p.38
Definition and Classification of Food Allergies

What type of disease is celiac disease?

A serious, genetic, autoimmune disease.

p.38
Immune System Response to Allergens

What triggers celiac disease?

Consuming gluten found in wheat, barley, and rye.

p.2
Common Allergenic Foods

Are peanuts the only food that can cause a severe reaction?

No, many foods can cause severe reactions.

p.24
Symptoms and Severity of Allergic Reactions

What is the local response in an IgE mediated allergy?

It includes symptoms like itchiness and localized swelling.

p.41
Diagnosis of Food Allergies

What is added after the patient's serum in the RAST test?

Radiolabeled anti-human IgE antibody.

p.16
Common Allergenic Foods

How many other foods can cause allergic reactions?

More than 160.

p.34
Immune System Response to Allergens

What occurs when enough cross-linking of IgE happens?

Mast cells explode with histamine and other inflammatory substances.

p.21
Immune System Response to Allergens

What is the primary function of the immune system?

To protect the body from foreign invaders.

p.9
Prevalence of Food Allergies Worldwide

What percentage of all Americans have food allergies?

4% (approximately 12 million).

p.18
Definition and Classification of Food Allergies

What are some characteristics of proteins that cause food allergies?

They are heat-resistant, resistant to digestion/proteolysis, and resistant to extremes in pH.

p.5
Symptoms and Severity of Allergic Reactions

What are some common signs and symptoms of a food allergy?

Itchiness, swelling of the tongue, vomiting, diarrhea, hives, trouble breathing, or low blood pressure.

p.4
Definition and Classification of Food Allergies

What type of adverse reaction is food intolerance classified as?

Non-immune mediated.

p.47
Prevention Strategies for Food Allergies

Why is education important in allergy prevention?

To teach the general public about allergies and ways to prevent them.

p.34
Symptoms and Severity of Allergic Reactions

What symptoms can occur during an allergic response?

Wheezing, sneezing, coughing, itchy eyes, runny nose, and shortness of breath.

p.42
Diagnosis of Food Allergies

What is the reaction pattern observed in patients allergic to eggs during food challenges?

Reaction pattern during double-blind, placebo-controlled food challenge.

p.30
Prevalence of Food Allergies Worldwide

How many patients were admitted with a physician-reported diagnosis of anaphylaxis over 11 years?

A total of 2,854 patients.

p.26
Immune System Response to Allergens

Which cells are persistently infiltrated during a chronic inflammatory response?

Mast cells, leukocytes, and dendritic cells.

p.5
Anaphylaxis and Emergency Response

What is anaphylaxis?

A serious allergic reaction that is rapid in onset and may cause death.

p.9
Prevalence of Food Allergies Worldwide

What is the prevalence of cow milk allergy in the US?

2.5%.

p.26
Immune System Response to Allergens

How does allergic inflammation affect tissue cells?

It affects epithelial cells and muscle cells, causing chronic structural changes.

p.25
Immune System Response to Allergens

What types of leukocytes migrate to the initial site during the late phase response?

Neutrophils, Lymphocytes, Eosinophils, Macrophages.

p.23
Immune System Response to Allergens

What type of T-cell is involved in IgE mediated allergy?

Th2 (a type of T-cell).

p.3
Immune System Response to Allergens

What happens during the late-phase of an allergic reaction?

Inflammatory response that occurs hours after the initial reaction.

p.23
Immune System Response to Allergens

What do B-cells produce in IgE mediated allergies?

IgE (Immunoglobulin E).

p.1
Diagnosis of Food Allergies

How are food allergies diagnosed?

Through medical history, skin tests, and blood tests.

p.48
Prevention Strategies for Food Allergies

Who organized the Hong Kong Allergy Association?

Patients with allergy, their caregivers, and medical professionals.

p.2
Prevention Strategies for Food Allergies

Can cooking foods make them less allergenic?

Yes, cooking can make foods less allergenic.

p.36
Common Allergenic Foods

What triggers Celiac Disease?

Hypersensitivity to gluten found in wheat, barley, rye, and certain other grains.

p.41
Diagnosis of Food Allergies

What does the RAST test detect?

Specific IgE antibodies to suspected or known allergens.

p.17
Common Allergenic Foods

What is the risk percentage of allergic reactions to shellfish?

75%.

p.24
Anaphylaxis and Emergency Response

What is anaphylaxis in the context of allergic reactions?

Anaphylaxis is a severe, potentially life-threatening allergic reaction.

p.41
Diagnosis of Food Allergies

What does the amount of radioactivity indicate in the RAST test?

It is proportional to the serum IgE for the allergen.

p.18
Definition and Classification of Food Allergies

Can foods contain multiple allergens?

Yes, foods can have one or many allergens in them.

p.27
Symptoms and Severity of Allergic Reactions

What is angioedema?

A cutaneous symptom characterized by swelling beneath the skin.

p.37
Symptoms and Severity of Allergic Reactions

Can Celiac Disease be asymptomatic?

Yes, it can be potentially asymptomatic.

p.38
Prevalence of Food Allergies Worldwide

What is the prevalence of celiac disease in Europe?

5 million people.

p.21
Immune System Response to Allergens

What are antibodies?

Proteins produced by B-cells that help identify and neutralize foreign objects like bacteria and viruses.

p.9
Prevalence of Food Allergies Worldwide

What is the prevalence of egg allergy in the US?

1.3%.

p.27
Symptoms and Severity of Allergic Reactions

What respiratory symptom is associated with IgE-mediated reactions?

Rhinitis.

p.9
Prevalence of Food Allergies Worldwide

What is the prevalence of peanut allergy in the US?

0.8%.

p.27
Symptoms and Severity of Allergic Reactions

What is laryngeal edema?

Swelling in the larynx, a respiratory symptom of IgE-mediated reactions.

p.40
Diagnosis of Food Allergies

What is a drawback of the Skin Prick Test?

It has a high false positive rate.

p.3
Common Allergenic Foods

What are allergenic foods?

Foods that can trigger allergic reactions in susceptible individuals.

p.24
Immune System Response to Allergens

What happens to blood vessels during an acute allergic response?

Vasodilation and increased vascular permeability occur.

p.23
Immune System Response to Allergens

What occurs during the sensitization stage?

Production of IgE and binding of IgE to Mast cells.

p.23
Immune System Response to Allergens

What happens during mast cell activation?

Allergen binds to IgE on Mast cells, triggering the release of mediators.

p.1
Prevention Strategies for Food Allergies

What are some prevention strategies for food allergies?

Early introduction of allergenic foods and breastfeeding.

p.13
Natural History and Risk Factors of Food Allergies

What is the risk of allergy in infants fed with intact cow's milk protein during the first week of life?

5-15%.

p.24
Symptoms and Severity of Allergic Reactions

What is a systemic response in an allergic reaction?

A systemic response can include widespread symptoms like low blood pressure and throat swelling.

p.22
Immune System Response to Allergens

What are mediators in the context of mast cells?

Products released by mast cells that cause allergic symptoms.

p.38
Prevalence of Food Allergies Worldwide

How many people are affected by celiac disease in general?

1 in 133 people.

p.25
Symptoms and Severity of Allergic Reactions

What is a symptom of the late phase response?

Further inflammation.

p.17
Common Allergenic Foods

What are examples of other legumes that may cause allergic reactions?

Peas, lentils, beans.

p.2
Management and Treatment of Food Allergies

Is it safe to have even one little bite of an allergenic food?

No, even one little bite is not okay.

p.38
Management and Treatment of Food Allergies

Is there a cure for celiac disease?

No, there is no cure.

p.17
Common Allergenic Foods

What are examples of other tree nuts that may cause allergic reactions?

Cashew, hazelnut.

p.1
Anaphylaxis and Emergency Response

What is anaphylaxis?

A severe, potentially life-threatening allergic reaction.

p.2
Natural History and Risk Factors of Food Allergies

Can food allergies develop at any age?

Yes, they can develop at any age.

p.13
Natural History and Risk Factors of Food Allergies

What is the risk of allergy in infants fed with intact cow's milk protein compared to breast-fed infants?

4 times higher in infants fed with intact cow's milk protein.

p.36
Symptoms and Severity of Allergic Reactions

What is a characteristic feature of the small intestine in Celiac Disease?

Scalloping of folds and a 'cracked-mud' appearance.

p.41
Diagnosis of Food Allergies

What is the first step in the RAST test method?

The suspected allergen is bound to an insoluble material.

p.41
Diagnosis of Food Allergies

What is washed away after the binding process in the RAST test?

Unbound anti-human IgE antibodies.

p.1
Definition and Classification of Food Allergies

What are food allergies?

Immune system reactions that occur after consuming certain foods.

p.1
Immune System Response to Allergens

What triggers food allergies?

Proteins in certain foods that the immune system mistakenly identifies as harmful.

Study Smarter, Not Harder
Study Smarter, Not Harder