What is the primary function of the endomembrane system?
To produce, degrade, store, and export biological molecules, and to degrade potentially harmful substances.
What are Okazaki fragments?
Short DNA fragments synthesized on the lagging strand during replication.
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p.1
The Endomembrane System

What is the primary function of the endomembrane system?

To produce, degrade, store, and export biological molecules, and to degrade potentially harmful substances.

p.11
Cell Cycle and Phases of Cell Division

What are Okazaki fragments?

Short DNA fragments synthesized on the lagging strand during replication.

p.8
The Endomembrane System

What is the primary function of transmembrane proteins?

Act as receptors for chemical messengers, transport proteins, and in cell-to-cell recognition.

p.11
Cell Cycle and Phases of Cell Division

During which phase does DNA replication occur?

S phase.

p.2
Cytoskeleton Structure and Function

What is the cytoskeleton?

An elaborate network of rods running through the cytosol, providing support and enabling cell movement.

p.11
Cell Cycle and Phases of Cell Division

What happens during the G2 phase of interphase?

Enzymes and proteins needed for division are synthesized and centriole replication is completed.

p.2
Cytoskeleton Structure and Function

What role do microfilaments play in muscle cells?

They interact with myosin to generate contractile forces.

p.4
Cilia and Flagella

What are basal bodies?

Basal bodies are centrioles that form the bases of cilia and flagella.

p.4
Cilia and Flagella

Describe the '9 + 2' pattern found in cilia and flagella.

The '9 + 2' pattern consists of nine doublets of microtubules encircling one central pair.

p.5
Nucleus Structure and Function

What happens to anucleate cells in the bloodstream?

They cannot reproduce and live for only three to four months before deteriorating.

p.3
Centrosome and Centrioles

What is the function of the centrosome matrix?

It generates microtubules and organizes the mitotic spindle during cell division.

p.1
The Endomembrane System

Which organelles are included in the endomembrane system?

Endoplasmic reticulum (ER), Golgi apparatus, secretory vesicles, lysosomes, and the nuclear envelope.

p.10
Cell Cycle and Phases of Cell Division

What are the main phases of the cell cycle?

Interphase and the mitotic phase.

p.5
Cilia and Flagella

What is the primary function of cilia?

To move substances across the free cell surface.

p.10
Cell Cycle and Phases of Cell Division

What is the role of the S subphase in interphase?

DNA replication occurs during the S subphase.

p.7
Nucleus Structure and Function

What is the fate of a cell that ejects or loses its nucleus?

The cell typically cannot survive because the nucleus contains the genetic material necessary for cell function.

p.9
Cytoskeleton Structure and Function

What is the function of intermediate filaments?

Stable cytoskeletal elements that resist mechanical forces acting on the cell.

p.2
Cytoskeleton Structure and Function

What are microtubules made of?

Hollow tubes of spherical protein subunits called tubulin.

p.8
The Endomembrane System

What does the Golgi apparatus do?

Packages, modifies, and segregates proteins for secretion, lysosomes, and plasma membrane incorporation.

p.9
Cilia and Flagella

How does a flagellum differ from a cilium?

A flagellum is longer than a cilium; the only example in humans is the sperm tail, which propels the cell.

p.6
Nucleus Structure and Function

What is the nuclear envelope?

A double membrane barrier that surrounds the nucleus.

p.10
Cell Cycle and Phases of Cell Division

What occurs during the G1 subphase of interphase?

The cell is metabolically active, synthesizing proteins rapidly and growing.

p.4
Cilia and Flagella

What are flagella and how do they differ from cilia?

Flagella are longer projections formed by centrioles, while cilia are shorter and occur in larger numbers. Flagella propel the cell itself, whereas cilia propel substances across a cell's surface.

p.5
Microvilli and Their Role in Absorption

What is the core structure of microvilli?

Bundled actin filaments.

p.8
The Endomembrane System

What do ribosomes do?

Sites of protein synthesis.

p.8
The Endomembrane System

What is the role of the rough endoplasmic reticulum?

Synthesis of proteins and phospholipids, and transport of proteins to the Golgi apparatus.

p.3
Cytoskeleton Structure and Function

What role do microtubules play in the cell?

They determine the overall shape of the cell and the distribution of cellular organelles.

p.3
Cytoskeleton Structure and Function

How do motor proteins move along microtubules?

They move 'hand over hand', gripping and releasing at new sites.

p.11
Cell Cycle and Phases of Cell Division

What is the role of DNA polymerase in DNA replication?

It positions complementary free nucleotides along the template strands.

p.8
The Endomembrane System

What is the structure of the plasma membrane?

A double layer of phospholipids with embedded cholesterol and proteins.

p.1
Lysosomes and Their Functions

What happens when lysosomes rupture?

The cell undergoes autolysis, digesting itself.

p.8
The Endomembrane System

What is the cytoplasm?

The cellular region between the nuclear and plasma membranes, containing cytosol, organelles, and inclusions.

p.11
Cell Cycle and Phases of Cell Division

What is the purpose of having multiple origins of replication in human DNA?

To greatly increase the speed of replication.

p.10
Nucleus Structure and Function

What is the nucleolus composed of?

Ribosomal RNA and proteins.

p.5
Nucleus Structure and Function

What is a multinucleate cell?

A cell that has many nuclei, often found in skeletal muscle and some liver cells.

p.2
Cytoskeleton Structure and Function

Where do most microtubules radiate from?

The centrosome or cell center.

p.4
Cilia and Flagella

What is the function of cilia in the respiratory tract?

Ciliated cells in the respiratory tract propel mucus laden with dust particles and bacteria upward away from the lungs.

p.7
Nucleus Structure and Function

What are nucleoli and where are they found?

Nucleoli are dark-staining spherical bodies within the nucleus where ribosomal subunits are assembled.

p.5
Cilia and Flagella

What are the phases of ciliary motion?

Power stroke and recovery stroke.

p.1
Lysosomes and Their Functions

What is Tay-Sachs disease?

A rare neurodegenerative disorder caused by lysosomes lacking an enzyme needed to break down a specific glycolipid in nerve cell membranes.

p.5
Nucleus Structure and Function

What is the role of the nucleus in a cell?

It acts as the control center, containing genetic instructions for protein synthesis.

p.9
Cytoskeleton Structure and Function

What are microfilaments composed of and their function?

Fine filaments composed of actin; involved in muscle contraction and intracellular movement.

p.4
Cilia and Flagella

How do cilia move substances across cell surfaces?

Cilia move substances in one direction through a rhythmic alternating motion of a propulsive power stroke and a recovery stroke.

p.10
Cell Cycle and Phases of Cell Division

What happens during the mitotic phase?

The cell divides into two cells.

p.11
Cell Cycle and Phases of Cell Division

What must occur before a cell can divide?

DNA must be replicated exactly.

p.6
Nucleus Structure and Function

What are nuclear pores?

Punctures in the nuclear envelope that regulate entry and exit of molecules.

p.3
Centrosome and Centrioles

What is the function of the centrosome?

It acts as a microtubule organizing center.

p.3
Centrosome and Centrioles

What are centrioles composed of?

Nine triplets of microtubules.

p.7
Chromatin and DNA Packaging

What role do histone proteins play in the nucleus?

Histone proteins package and regulate DNA, playing an important role in gene regulation.

p.2
Cytoskeleton Structure and Function

What are intermediate filaments composed of?

Twisted units of tetramer fibrils.

p.2
Cytoskeleton Structure and Function

What is the main function of intermediate filaments?

To act as internal cables that resist pulling forces on the cell.

p.10
Cell Cycle and Phases of Cell Division

What is the significance of the G2/M checkpoint?

It is a critical point where the cell checks for DNA damage and ensures all DNA is replicated before mitosis.

p.5
Nucleus Structure and Function

What is the average diameter of the nucleus?

5 μm.

p.9
Microvilli and Their Role in Absorption

What is the purpose of microvilli?

Tubular extensions of the plasma membrane that increase surface area for absorption.

p.11
Cell Cycle and Phases of Cell Division

What is the replication fork?

The point at which the DNA strands separate as hydrogen bonds are broken.

p.6
Nucleus Structure and Function

What is the role of the nuclear pore complex?

Forms an aqueous transport channel and regulates molecular transport.

p.7
Cell Cycle and Phases of Cell Division

What happens to chromatin when a cell prepares to divide?

Chromatin coils and condenses to form short, barlike bodies called chromosomes.

p.5
Microvilli and Their Role in Absorption

What do microvilli do?

Increase the plasma membrane surface area.

p.9
Cytoskeleton Structure and Function

What are microtubules made of and their role?

Cylindrical structures made of tubulin proteins; support the cell, give it shape, and are involved in intracellular movements.

p.1
Lysosomes and Their Functions

What metabolic function do lysosomes perform related to glycogen?

They degrade glycogen at a relatively constant rate.

p.3
Centrosome and Centrioles

What distinguishes the centrosome of spermatozoa from typical centrioles?

It contains a proximal centriole and a distal centriole with an atypical structure.

p.10
Cell Cycle and Phases of Cell Division

Why is interphase sometimes referred to as the 'resting phase'?

Because early cytologists thought cells were inactive, but it is actually a period of metabolic activity.

p.8
The Endomembrane System

What is the function of peroxisomes?

Detoxify toxic substances and break down hydrogen peroxide using catalase.

p.6
Nucleus Structure and Function

What are the three recognizable regions or structures of the nucleus?

Nuclear envelope, nucleoli, and chromatin.

p.7
Chromatin and DNA Packaging

What is the composition of chromatin?

Chromatin is composed of approximately 30% DNA, 60% globular histone proteins, and 10% RNA chains.

p.2
Cytoskeleton Structure and Function

What are the three types of rods in the cytoskeleton?

Microfilaments, intermediate filaments, and microtubules.

p.2
Cytoskeleton Structure and Function

What protein makes up microfilaments?

Actin.

p.3
Cytoskeleton Structure and Function

How do motor proteins function in relation to microtubules?

They move and reposition organelles along the microtubules powered by ATP.

p.10
Nucleus Structure and Function

What is the function of the nuclear envelope?

It separates the nucleoplasm from the cytoplasm and regulates the passage of substances to and from the nucleus.

p.3
Centrosome and Centrioles

What unique structure do centrioles form the bases of?

Cilia and flagella.

p.3
Centrosome and Centrioles

What is the shape of the centriole pair?

Oriented at right angles to each other.

p.8
The Endomembrane System

What is the function of the smooth endoplasmic reticulum?

Site of lipid and steroid synthesis, lipid metabolism, drug detoxification, and Ca2+ storage.

p.9
The Endomembrane System

What do inclusions in the cytoplasm store?

Varied substances including stored nutrients like lipid droplets and glycogen granules.

p.9
Nucleus Structure and Function

What is the nucleus and its primary function?

The largest organelle, surrounded by the nuclear envelope; it controls the cell and transmits genetic information.

p.1
Lysosomes and Their Functions

What role do lysosomes play in a cell?

They function as the cell's 'demolition crew' by digesting particles, degrading stressed or dead cells, and performing metabolic functions.

p.7
Chromatin and DNA Packaging

What are nucleosomes?

Nucleosomes are the fundamental units of chromatin, consisting of clusters of eight histone proteins connected by a DNA molecule.

p.9
Lysosomes and Their Functions

What are lysosomes and their function?

Membranous sacs containing acid hydrolases; sites of intracellular digestion.

p.8
The Endomembrane System

What is the function of mitochondria?

Site of ATP synthesis; known as the powerhouse of the cell.

p.7
Chromatin and DNA Packaging

What is the significance of extended chromatin?

Extended chromatin segments are active and expose different DNA segments for synthesizing proteins or RNA species.

p.4
Cilia and Flagella

What role do dynein arms play in cilia and flagella?

Dynein arms are motor proteins that produce the movement of the cilium or flagellum by gripping and pushing adjacent doublets.

p.5
Nucleus Structure and Function

What are the components of the nucleus?

Nuclear envelope, nucleolus, and chromatin.

p.6
Nucleus Structure and Function

What is the function of the nuclear lamina?

Maintains the shape of the nucleus and organizes DNA.

p.1
Lysosomes and Their Functions

What process is referred to as autophagy?

The degradation of stressed or dead cells and worn-out organelles by lysosomes.

p.6
Nucleus Structure and Function

What is nucleo-plasm?

The jellylike fluid enclosed by the nuclear envelope.

p.6
Nucleus Structure and Function

How does the nuclear envelope compare to other cell membranes?

It is selectively permeable but allows substances to pass more freely.

p.4
Cilia and Flagella

What is the only flagellated cell in the human body?

The sperm cell, which has one propulsive flagellum commonly called a tail.

p.1
Lysosomes and Their Functions

What is a physical finding associated with Tay-Sachs disease?

A 'cherry red spot' on the macula of the retina.

p.6
Nucleus Structure and Function

What guides the transport of molecules through nuclear pores?

Soluble transport proteins.

p.7
Chromatin and DNA Packaging

How do methyl and acetyl groups affect histone proteins?

Methyl groups can shut down nearby DNA, while acetyl groups expose different DNA segments for gene expression.

p.4
Cilia and Flagella

What initiates the formation of cilia in a cell?

Centrioles multiply and line up beneath the plasma membrane at the cell's exposed surface, leading to the sprouting of microtubules.

p.11
Cell Cycle and Phases of Cell Division

What is the significance of the G2/M checkpoint?

The cell ensures that all DNA is replicated and damaged DNA has been repaired before division.

p.6
Nucleus Structure and Function

What types of molecules can pass through nuclear pores?

Small molecules, protein molecules, and RNA molecules.

p.11
Cell Cycle and Phases of Cell Division

What happens during the uncoiling step of DNA replication?

Enzymes unwind the DNA molecule, forming a replication bubble.

p.10
Chromatin and DNA Packaging

What is chromatin made of?

DNA and histone proteins.

p.9
Centrosome and Centrioles

What are centrioles and their role during mitosis?

Paired cylindrical bodies that organize the microtubule network and form the spindle and asters during cell division.

p.2
Cytoskeleton Structure and Function

What is the dynamic nature of microtubules?

They constantly grow, disassemble, and reassemble.

p.9
Cilia and Flagella

What is the function of cilia?

Short cell-surface projections that create a unidirectional current to propel substances across cell surfaces.

Study Smarter, Not Harder
Study Smarter, Not Harder