How does lymph enter and exit a lymph node?
Lymph enters through several afferent lymphatic vessels and exits through one to two efferent lymphatic vessels at the hilum.
What are the sinuses in the lymph node and their function?
Sinuses are spaces that support the flow of lymph, beginning at the sub-capsular sinus and branching into trabecular sinuses in the cortex and medullary sinuses in the medulla.
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Lymph Nodes: Structure and Immune Function

How does lymph enter and exit a lymph node?

Lymph enters through several afferent lymphatic vessels and exits through one to two efferent lymphatic vessels at the hilum.

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Lymph Nodes: Structure and Immune Function

What are the sinuses in the lymph node and their function?

Sinuses are spaces that support the flow of lymph, beginning at the sub-capsular sinus and branching into trabecular sinuses in the cortex and medullary sinuses in the medulla.

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Tonsils and Lymphatic Nodules

Where are tonsils located?

Tonsils are located in the pharyngeal region at the top of the throat.

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Primary and Secondary Lymphatic Organs

What are the secondary lymphatic organs?

The spleen, lymph nodes, tonsils, and lymphatic nodules.

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Lymph Nodes: Structure and Immune Function

How are lymph nodes distributed in the body?

Lymph nodes are widely distributed in the body and usually occur in clusters or chains.

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Lymph Nodes: Structure and Immune Function

How does lymph enter the lymph nodes?

Lymph follows afferent lymphatic vessels to get into the subcapsular sinus of lymph nodes.

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Lymphatic Ducts: Structure and Function

Where do the lymphatic ducts empty their lymph?

Into venous circulation at the junction of the internal jugular and subclavian veins on each side of the body.

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Formation of Lymph

Why is an alternative drainage route required for tissue fluid?

To prevent excess fluid from accumulating in tissues, as not all tissue fluid re-enters the blood capillaries.

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Primary and Secondary Lymphatic Organs

Which organs are part of the lymphatic system?

The thymus, spleen, lymph nodes, tonsils, and lymphatic nodules.

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Lymph Nodes: Structure and Immune Function

What are the main structural components of a lymph node when cut at a sagittal plane?

An outer cortex and an inner medulla.

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Tonsils and Lymphatic Nodules

What is the function of the ring of lymphoid tissue formed by the tonsils?

To collect and remove pathogens entering the body from inhaled air via the nasal cavity and swallowed food via the oral cavity.

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Tonsils and Lymphatic Nodules

What is the function of lymphocytes in lymphatic nodules?

To kill pathogens that travel along the digestive tract and generate a diverse range of memory lymphocytes from sampling different antigens.

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Lymphatic System and Cardiovascular Association

How does the lymphatic system work with the cardiovascular system?

It forms a circulatory unit that returns fluid leaked from blood vessels back to the blood and drains excess fluid and proteins away from tissues.

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Lymph Nodes: Structure and Immune Function

What cells predominantly occupy the superficial layer of the lymph node's cortex?

B-cells and macrophages.

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Lacteals and Fat Absorption

What are lacteals and where are they located?

Lacteals are specialized lymphatic vessels present in the intestines, where food absorption takes place.

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Primary and Secondary Lymphatic Organs

What are the primary lymphatic organs and their functions?

Red bone marrow and thymus are primary lymphatic organs where maturation of lymphocytes takes place.

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Lymph Nodes: Structure and Immune Function

What is the primary function of lymph nodes?

Filtering out foreign substances and killing pathogens such as bacteria and viruses in the lymph.

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Lymph Nodes: Structure and Immune Function

What is the role of the reticular meshwork in lymph nodes?

It supports the structure of the lymph node and enhances the filtering effect by causing lymph to flow slowly.

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Tonsils and Lymphatic Nodules

Where can lymphatic nodules be found besides specialized lymphoid organs?

In the connective tissue of easily infected mucous membranes.

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Lymphatic Ducts: Structure and Function

What are the two main lymphatic ducts in the body?

The right lymphatic duct and the thoracic duct.

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Lymphatic Ducts: Structure and Function

Where does the thoracic duct arise from?

It arises as an enlarged sac called the cisterna chyli, situated at the first and second lumbar level.

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Primary and Secondary Lymphatic Organs

What structural feature do the spleen, lymph nodes, and thymus share?

They all have a dense, fibrous capsule around them, providing physical support and forming paths for blood vessels, efferent lymphatic vessels, and nerves.

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Tonsils and Lymphatic Nodules

What are the four groups of tonsils?

Pharyngeal tonsil (or adenoid), tubal tonsils, palatine tonsils, and lingual tonsils.

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Tonsils and Lymphatic Nodules

What are Peyer's patches?

Aggregates of lymphoid nodules found in the ileum of the small intestine.

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Lymphatic Ducts: Structure and Function

What is the function of the right lymphatic duct?

It drains lymph from the right upper part of the body (one-fourth of lymph drainage).

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Lacteals and Fat Absorption

What happens to the lymph inside lacteals when it is rich in lipid?

It turns milky, hence lacteals are also known as white and milky veins.

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Lymphatic System and Cardiovascular Association

What are the main functions of the lymphatic system?

The lymphatic system aids in circulation, body defense, and digestion.

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Lymph Nodes: Structure and Immune Function

What role do lymphocytes and macrophages play in the lymph nodes?

They monitor the contents of the lymph and clear harmful micro-organisms like pathogens or tumour cells.

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Primary and Secondary Lymphatic Organs

Where do B-lymphocytes and T-lymphocytes mature?

B-lymphocytes mature in the bone marrow, while T-lymphocytes mature in the thymus.

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Lymph Nodes: Structure and Immune Function

What role do lymph nodes play in the lymphatic system?

Lymph nodes filter and cleanse pathogens from the lymph.

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Lymph Nodes: Structure and Immune Function

How does lymph leave the lymph nodes?

Lymph flows into efferent lymphatic vessels to leave the lymph node after coursing through the medullary sinuses.

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Lacteals and Fat Absorption

What are lacteals and what is their function?

Lacteals are lymphatic vessels involved in the absorption of fat from digested food in the small intestine.

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Lymph Nodes: Structure and Immune Function

What is the normal size range of lymph nodes?

About 1 mm to 2 cm in length.

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Lymph Nodes: Structure and Immune Function

What cells are predominant in the deep cortex (paracortex) of the lymph node?

T-cells.

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Lymph Nodes: Structure and Immune Function

What happens to lymph after it enters the subcapsular sinus of lymph nodes?

It flows into trabecular sinuses close to the trabeculae and then into the medullary sinuses or diffuses through lymphatic nodules before reaching the medullary sinuses.

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Tonsils and Lymphatic Nodules

Which tonsils are the largest and most often infected in childhood?

The palatine tonsils.

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Lymphatic Ducts: Structure and Function

What is the function of the thoracic duct?

It drains lymph from the right lower part and the whole left side of the body (the remaining three-fourths of lymph drainage).

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Formation of Lymph

What is lymph and how is it formed?

Lymph is the interstitial fluid inside lymphatic vessels. It is formed when plasma passes through the capillary wall and enters the surrounding tissue, forming tissue fluid.

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Lymph Nodes: Structure and Immune Function

What are the two types of lymph nodes based on their location?

Superficial and deep lymph nodes.

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Tonsils and Lymphatic Nodules

What might be required if tonsils are repeatedly infected?

Surgical removal (tonsillectomy).

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Lacteals and Fat Absorption

What is the function of lacteals?

Lacteals are important for the absorption and transportation of lipids or chylomicrons in the body.

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