Renin is an enzyme produced by the juxtaglomerular cells, specifically from the granule cells.
Sympathetic beta 1 stimulation and decreased blood pressure.
Converts Angiotensinogen to Angiotensin 1, leading to the release of Angiotensin 2 and aldosterone.
Increased blood pressure, increased Na reabsorption, and increased water reabsorption.
Renin acts on the efferent arteriole and the adrenal gland.
ACE converts Angiotensin 1 to Angiotensin 2.
Low blood volume and low blood pressure, or high plasma K+ levels.
Increased Na reabsorption, increased water reabsorption, and increased K+ secretion into urine.
Low blood volume, low blood pressure, high Na+ levels, or the release of Angiotensin 2.
ADH acts on the principal cortical collecting duct cells and the distal tubule.
Opposite actions to Angiotensin 2, resulting in decreased aldosterone release and increased natriuresis and diuresis.
Aldosterone acts on the adrenal gland cortex and the distal tubule.
Increased water and urea reabsorption, and making the collecting duct permeable to water.
ANP/BNP acts on the afferent and efferent arterioles, and the collecting duct.
PTH acts on the distal tubule in the kidneys.
PTH increases Ca reabsorption from the kidney and decreases phosphate reabsorption.
Too much blood volume, which stretches the atria of the heart, leading to ANP release.
