What is Carpal Tunnel Syndrome (CTS)?
CTS is the most common entrapment neuropathy, occurring when the median nerve is compressed by the flexor retinaculum/transverse carpal ligament at the wrist.
What percentage of rheumatoid arthritis patients experience entrapment neuropathies?
Nearly half of patients with chronic rheumatoid arthritis experience entrapment neuropathies at some point in their lifetime.
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Carpal Tunnel Syndrome (CTS) Overview

What is Carpal Tunnel Syndrome (CTS)?

CTS is the most common entrapment neuropathy, occurring when the median nerve is compressed by the flexor retinaculum/transverse carpal ligament at the wrist.

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Entrapment Neuropathies in Rheumatoid Arthritis

What percentage of rheumatoid arthritis patients experience entrapment neuropathies?

Nearly half of patients with chronic rheumatoid arthritis experience entrapment neuropathies at some point in their lifetime.

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Entrapment Neuropathies in Rheumatoid Arthritis

What exacerbates ulnar nerve entrapment?

Elbow flexion and elevating the hand by resting the forearm on the head.

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Conservative and Surgical Management of Entrapment Neuropathies

What is a common treatment for Morton’s neuroma?

Wearing more supportive shoes and local steroid injections.

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Physical Examination and Diagnostic Tests for CTS

What physical examination signs are indicative of CTS?

Numbness in the index, middle, and radial side of the ring finger, positive Tinel’s sign, positive Phalen’s test, and positive direct median nerve compression test.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is the most likely nerve to be compressed in a patient with painless foot-drop?

The common peroneal nerve.

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Treatment Options for Carpal Tunnel Syndrome

What treatment method for carpal tunnel syndrome is discussed in the Cochrane Database review by Marshall S, Tardif G, and Ashworth N?

Local corticosteroid injection.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is a common cause of peroneal nerve palsy?

Compression over the head of the fibula from prolonged leg crossing.

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Conservative and Surgical Management of Entrapment Neuropathies

What do Scholten R J and colleagues review regarding carpal tunnel syndrome?

Surgical treatment options.

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Entrapment Neuropathies in Rheumatoid Arthritis

What causes pronator teres syndrome?

Compression of the median nerve by the pronator teres muscle at the forearm, resulting in proximal volar forearm pain and numbness in the thumb and index finger.

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Treatment Options for Carpal Tunnel Syndrome

What are the treatment options for thoracic outlet syndrome?

Treatment includes range of motion and strengthening exercises, avoidance of hyperabduction, botulinum toxin injections, and surgery for severe, refractory symptoms.

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Associated Diseases with Carpal Tunnel Syndrome

What diseases are associated with CTS as per the mnemonic PRAGMATIC?

Pregnancy, Rheumatoid arthritis, Acromegaly, Glucose (diabetes), Mechanical (overuse), Amyloid, Thyroid (myxedema), Infection (TB, fungal), Crystals (gout, pseudogout).

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Associated Diseases with Carpal Tunnel Syndrome

What are common causes of meralgia paresthetica?

Common causes include obesity, pregnancy, trauma, surgical injury, tight-fitting clothing, and diabetes mellitus.

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Diagnosis of Entrapment Neuropathies

What type of review did MacDermid J C and Wessel J conduct?

A systematic review of clinical diagnosis of carpal tunnel syndrome.

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Electrodiagnostic Studies in Neuropathy Evaluation

What is the role of electrodiagnostic studies in CTS?

They have a sensitivity of 85% and specificity of 95% for diagnosing CTS.

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Definition and Mechanism of Entrapment Neuropathies

What is 'Saturday night palsy'?

It refers to wrist-drop resulting from radial nerve entrapment, often occurring while the patient is intoxicated.

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Electrodiagnostic Studies in Neuropathy Evaluation

When are electrodiagnostic studies indicated?

They are indicated when the diagnosis is uncertain, to exclude radiculopathy or polyneuropathy, to follow treatment, or before surgery.

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Diagnosis of Entrapment Neuropathies

What are characteristic clinical features of entrapment neuropathies?

Features include dysesthesias, burning or tingling sensations, symptoms worse at night, and muscle weakness or atrophy as late findings.

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Treatment Options for Carpal Tunnel Syndrome

What are the nonsurgical treatment options for CTS?

Avoidance of repetitive wrist motion, cock-up wrist splints, anti-inflammatory medications, and ergonomic evaluation.

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Other Types of Entrapment Syndromes

What is piriformis syndrome?

It refers to sciatica caused by entrapment of the sciatic nerve by the piriformis muscle, often associated with overuse injuries.

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Definition and Mechanism of Entrapment Neuropathies

How does radial nerve entrapment occur?

It can occur due to improper positioning during anesthesia, sleeping on the arm, or improperly fitting crutches, leading to prolonged compression of the nerve.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is ulnar tunnel syndrome?

Compression of the ulnar nerve in Guyon’s canal at the wrist, resulting in symptoms similar to cubital tunnel syndrome.

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Diagnosis of Entrapment Neuropathies

What is the hyperabduction maneuver?

A test for thoracic outlet syndrome performed with the shoulder in abduction and external rotation to assess for symptoms.

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Surgical Management of Entrapment Neuropathies

What is the long-term success rate of surgical treatment for CTS?

Favorable in over 75% of patients.

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Physical Examination and Diagnostic Tests for CTS

What physical therapy techniques can be beneficial for piriformis syndrome?

Lateral stretching and strengthening.

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Diagnosis of Entrapment Neuropathies

What is the typical presentation of thoracic outlet syndrome (TOS)?

Electrodiagnostic studies are usually normal, and many normal individuals may have false-positive physical examination provocation tests, especially decreased pulse.

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Entrapment Neuropathies in Rheumatoid Arthritis

What condition is characterized by burning dysesthesias of the toes and sole of the foot, worse at night?

Tarsal tunnel syndrome.

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Diagnosis of Entrapment Neuropathies

What is the focus of the study by Kwon B C, Jung K I, and Baek G H?

Comparison of sonography and electrodiagnostic testing in the diagnosis of carpal tunnel syndrome.

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Carpal Tunnel Syndrome (CTS) Overview

What are the common symptoms of CTS?

Characteristic nocturnal dysesthesias (70%), sensory loss, weakness of thumb abduction, and pain radiating into the proximal arm (40%).

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Carpal Tunnel Syndrome (CTS) Overview

What percentage of CTS cases are bilateral?

Half of the patients.

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Diagnosis of Entrapment Neuropathies

How are entrapment neuropathies typically diagnosed?

Diagnosis is usually supported by characteristic symptoms and provocative maneuvers like Tinel’s sign, along with electrodiagnostic studies.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is thoracic outlet syndrome (TOS)?

A condition caused by vascular or neurologic compression, often resulting from trauma, repetitive strain, or anatomical abnormalities.

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Diagnosis of Entrapment Neuropathies

What is the Adson maneuver used for?

To diagnose thoracic outlet syndrome by palpating the radial pulse while the patient inhales deeply and extends the neck.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is the typical symptom of peroneal nerve palsy?

Foot drop.

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Diagnosis of Entrapment Neuropathies

What are some other conditions to consider when evaluating entrapment neuropathies?

Conditions include polyneuropathies, brachial plexopathy, radiculopathy, Raynaud’s phenomenon, chronic regional pain syndrome, vasculitis, and tendinitis.

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Diagnosis of Entrapment Neuropathies

What test can reproduce symptoms in a patient with tarsal tunnel syndrome?

Positive Tinel’s sign and positive tourniquet test.

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Surgical Management of Entrapment Neuropathies

What is the indication for surgical therapy in CTS?

Failure of conservative therapy, lifestyle limiting symptoms, and muscle weakness or atrophy.

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Associated Diseases with Carpal Tunnel Syndrome

What exacerbates symptoms in patients with Morton’s neuroma?

Walking on hard surfaces and wearing high heels.

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Entrapment Neuropathies in Rheumatoid Arthritis

How does rheumatoid arthritis relate to entrapment neuropathies?

Inflammation and swelling in rheumatoid arthritis can cause pressure on adjacent nerves, leading to entrapment neuropathies.

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Entrapment Neuropathies in Rheumatoid Arthritis

What symptoms are associated with suprascapular nerve entrapment?

Patients present with weakness in shoulder abduction and external rotation, and possible atrophy of the supraspinatus muscle.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is cubital tunnel syndrome?

Ulnar nerve compression at the elbow, leading to paresthesias in the little finger and ulnar side of the ring finger, weakness in grasping, and hypothenar atrophy.

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Physical Examination and Diagnostic Tests for CTS

What is the pooled sensitivity and specificity of Tinel’s sign for CTS?

Sensitivity of 50% and specificity of 77%.

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Definition and Mechanism of Entrapment Neuropathies

What is meralgia paresthetica?

It is a condition caused by compression of the lateral cutaneous nerve of the thigh, resulting in burning pain and dysesthesia over the anterolateral thigh.

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Carpal Tunnel Syndrome (CTS) Overview

What is the most common entrapment neuropathy?

Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy.

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Other Types of Entrapment Syndromes

What is the most likely diagnosis for a patient with pain and burning between the third and fourth toe?

Morton’s neuroma.

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Other Types of Entrapment Syndromes

What are the symptoms of piriformis syndrome?

Symptoms include pain over the buttocks radiating down the back of the leg, aggravated by sitting.

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Definition and Mechanism of Entrapment Neuropathies

What are entrapment neuropathies?

Entrapment neuropathies occur when a peripheral nerve is compressed within an enclosed anatomic space.

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Definition and Mechanism of Entrapment Neuropathies

What factors can lead to entrapment neuropathies?

Increased pressure, stretch, angulation, ischemia, or friction can lead to entrapment neuropathies.

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Diagnosis of Entrapment Neuropathies

What does a positive Adson maneuver indicate?

Diminution of the radial pulse and reproduction of symptoms, suggesting thoracic outlet syndrome.

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Other Types of Entrapment Syndromes

What condition is addressed in the study by Thomas J L and colleagues?

Morton’s intermetatarsal neuroma.

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Entrapment Neuropathies in Rheumatoid Arthritis

What is anterior interosseous nerve syndrome?

A condition where the anterior interosseous nerve, a motor branch of the median nerve, is compressed, leading to loss of distal thumb and index finger flexion and a characteristic flattened pinch sign.

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Conservative and Surgical Management of Entrapment Neuropathies

What is the treatment approach for short-duration entrapment neuropathies?

Most entrapment neuropathies of short duration can be treated conservatively.

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Other Types of Entrapment Syndromes

What do McGann S A, Flores R H, and Nashel D J discuss in their work?

Entrapment neuropathies and compartment syndromes.

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Conservative and Surgical Management of Entrapment Neuropathies

What is the focus of the systematic review by Piazzini D B and colleagues?

Conservative treatment of carpal tunnel syndrome.

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Definition and Mechanism of Entrapment Neuropathies

What topic do Shapiro B and Preston D cover in their publication?

Entrapment and compressive neuropathies.

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