What is the total fluid administered in Hour 3?
240 mL.
What does 3% saline indicate?
A hypertonic solution.
1/176
p.19
Maintenance Fluid Calculations

What is the total fluid administered in Hour 3?

240 mL.

p.5
Fluid Therapy in Surgery

What does 3% saline indicate?

A hypertonic solution.

p.17
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 75 kg?

115 mL/hr.

p.5
Fluid Therapy in Surgery

Which solution has the least impact on cell volume?

D. Lactated ringers.

p.28
Estimating Blood Loss

What is the expected increase in hematocrit after transfusing 2 units of PRBC?

Approximately 3%.

p.25
Estimating Blood Loss

What is the preoperative hematocrit level in the scenario?

36%.

p.25
Estimating Blood Loss

How do you calculate the maximum allowable blood loss?

Using the formula: (Preoperative hematocrit - Lowest allowable hematocrit) / Preoperative hematocrit x Blood volume.

p.30
Blood Bank Practices

What happens to ATP levels in stored PRBCs over time?

Decreased.

p.1
Electrolyte Concentrations

Where is sodium (Na+) primarily concentrated?

Extracellularly.

p.24
Estimating Blood Loss

What is the blood volume represented by a soaked laparotomy sponge?

100 mL of blood.

p.14
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 75 kg patient?

Approximately 3,000 mL per day.

p.13
Fluid Therapy in Surgery

What type of loss is included in surgical loss during fluid therapy?

Losses not including blood loss.

p.17
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 100 kg?

140 mL/hr.

p.30
Blood Bank Practices

What happens to potassium levels in stored PRBCs over time?

Increased.

p.22
Estimating Blood Loss

How do you estimate estimated blood loss (EBL) using soaked gauze?

15 soaked 4 x 4's and 3 soaked lap pads.

p.3
Electrolyte Concentrations

What role does calcium play in plasma potassium concentration?

Calcium administration does not decrease plasma potassium concentration.

p.4
Fluid Therapy in Surgery

What happens to cells in a hypertonic solution?

Cells lose water and shrink.

p.9
Estimating Blood Loss

What is the estimated blood loss (EBL) addressed in the options?

2000 mL.

p.19
Maintenance Fluid Calculations

What is the maintenance fluid calculation for an 80 kg patient?

40 + 20 + 60 = 120 ml/hr.

p.21
Fluid Therapy in Surgery

What is the maintenance fluid calculation for a 60 kg patient?

40 + 20 + 40 = 100 ml/hr.

p.15
Maintenance Fluid Calculations

How is the maintenance rate calculated for the second 10 kg of body weight?

2 ml x 10 kg = 20 ml/hr.

p.20
Fluid Therapy in Surgery

What is the total fluid plan for a 4-hour surgical case?

Sum of hourly maintenance, fluid deficit, and anticipated surgical fluid loss over 4 hours.

p.34
Estimating Blood Loss

What is the patient's hemoglobin and hematocrit (H/H) preoperatively?

Hemoglobin 12 and hematocrit 36.

p.35
Fluid Therapy in Surgery

How long has the patient been NPO?

8 hours.

p.36
Enhanced Recovery After Surgery (ERAS)

What is the main focus of Enhanced Recovery After Surgery (ERAS)?

To improve recovery outcomes for patients undergoing surgery.

p.8
Estimating Blood Loss

What volume of colloid is suggested in the options?

100 mL.

p.23
Estimating Blood Loss

How much irrigation was used according to the surgeon?

200 ml.

p.6
Electrolyte Concentrations

What is the osmolarity of D5 ½ NS?

432 mOsm/L.

p.13
Fluid Therapy in Surgery

What should be considered regarding preexisting conditions in fluid therapy?

Preexisting fluid deficits.

p.17
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 60 kg?

100 mL/hr.

p.29
Transfusion Guidelines and Effects

What is the expected increase in hemoglobin from administering 1 unit of PRBC?

1 g/dL.

p.2
Electrolyte Concentrations

How can electrolyte imbalances occur?

Through dehydration, excessive sweating, certain medications, or underlying health conditions.

p.22
Estimating Blood Loss

What additional volume should be considered for irrigation during EBL estimation?

200 ml of irrigation used.

p.4
Fluid Therapy in Surgery

What is the effect of isotonic solutions on cell volume?

Isotonic solutions do not change cell volume.

p.26
Estimating Blood Loss

How is the maximum allowable blood loss (ABL) calculated?

ABL = [EBV x (Preoperative hematocrit - Lowest allowable hematocrit)] / Preoperative hematocrit.

p.19
Fluid Therapy in Surgery

What is the surgical loss of fluid during the procedure?

320 ml/hr.

p.20
Maintenance Fluid Calculations

What is the fluid deficit for a patient NPO for 12 hours?

12 hours x hourly maintenance rate.

p.34
Fluid Therapy in Surgery

What surgical procedure is planned for the patient?

Total abdominal hysterectomy.

p.20
Fluid Therapy in Surgery

How do you distribute fluids over the 4-hour surgical period?

Divide total fluid volume by 4 for each hour.

p.34
Fluid Therapy in Surgery

What is the patient's past medical history relevant to this case?

Motor vehicle accident (MVA) 10 years ago resulting in paralysis.

p.37
Enhanced Recovery After Surgery (ERAS)

What routine procedure should be avoided in the preoperative period?

Routine mechanical bowel preparation.

p.37
Enhanced Recovery After Surgery (ERAS)

What type of analgesia is recommended to limit opioid utilization?

Multimodal analgesia agents.

p.8
Estimating Blood Loss

What volume of PRBCs is suggested in the options?

1500 mL.

p.6
Electrolyte Concentrations

What is the K+ concentration in Plasma-Lyte?

5 mEq/L.

p.33
Estimating Blood Loss

What is the estimated blood volume of a 154 lb male that is 6'0” tall?

Approximately 6.5 liters.

p.13
Fluid Therapy in Surgery

What does 'normal losses' refer to in fluid therapy?

Maintenance requirements for fluid replacement.

p.28
Estimating Blood Loss

What is the expected increase in hemoglobin after transfusing 2 units of PRBC?

Approximately 1 g/dL.

p.7
Impact of Hypermagnesemia on Anesthesia

How does hypermagnesemia affect acetylcholine (Ach) release at the motor end plate?

It increases Ach release.

p.7
Impact of Hypermagnesemia on Anesthesia

Which statement is false regarding the anesthesia impact of hypermagnesemia?

D. None of the above.

p.27
Massive Transfusion Protocol

What electrolyte changes are expected during a massive transfusion protocol?

Hypocalcemia, hyperkalemia, and hypomagnesemia.

p.27
Massive Transfusion Protocol

What electrolyte imbalance can result from the dilution effect of massive transfusion?

Hypomagnesemia.

p.26
Estimating Blood Loss

What is the estimated blood volume (EBV) for a 90 kg male?

6300 ml.

p.9
Estimating Blood Loss

What is the purpose of colloid solutions in fluid therapy?

To maintain oncotic pressure and expand blood volume.

p.15
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 60 kg patient?

100 ml/hr.

p.31
Blood Bank Practices

What happens to 2, 3 DPG levels in stored PRBCs over time?

Decreased (↓).

p.21
Fluid Therapy in Surgery

What is the surgical loss rate during the procedure?

480 ml/hr.

p.37
Enhanced Recovery After Surgery (ERAS)

What is the goal during the intraoperative period of ERAS?

To decrease the physiologic stress response to surgery.

p.16
Maintenance Fluid Calculations

How is the maintenance fluid calculated for the first 10 kg of body weight for a 15 kg patient?

4 ml x 10 kg = 40 ml/hr.

p.6
Electrolyte Concentrations

What is the osmolarity of D5W?

253 mOsm/L.

p.23
Estimating Blood Loss

What is the total estimated blood loss calculation?

150 ml + 300 ml + 600 ml = 1050 ml.

p.5
Fluid Therapy in Surgery

What is D5 ½ NS?

5% dextrose in 0.45% saline.

p.2
Electrolyte Concentrations

What are electrolytes?

Minerals in the body that carry an electric charge.

p.7
Impact of Hypermagnesemia on Anesthesia

What sympathetic response does hypermagnesemia blunt during laryngoscopy?

It blunts the sympathetic response.

p.22
Estimating Blood Loss

What volume of fluid was collected in the suction canister?

800 ml.

p.1
Electrolyte Concentrations

What is the extracellular concentration of potassium (K+)?

4 mEq/L.

p.26
Estimating Blood Loss

What is the lowest allowable hematocrit in this scenario?

28%.

p.9
Estimating Blood Loss

What does PRBC stand for?

Packed Red Blood Cells.

p.19
Maintenance Fluid Calculations

What is the total fluid administered in Hour 2?

240 mL.

p.19
Fluid Therapy in Surgery

What is the total fluid administered during the first three surgical hours?

Total: 920 mL (Hour 1) + 680 mL (Hour 2) + 680 mL (Hour 3).

p.21
Fluid Therapy in Surgery

What is the total fluid administered in the second hour of surgery?

300 ml.

p.35
Fluid Therapy in Surgery

What is the diagnosis in the case scenario?

Femoral neck fracture.

p.35
Fluid Therapy in Surgery

What is the patient's height and weight?

6'1" and 90 kg.

p.35
Estimating Blood Loss

What is the maximum blood loss indicated in the scenario?

Lowest HCT 26%.

p.16
Maintenance Fluid Calculations

What is the maintenance fluid calculation for the remaining 5 kg of body weight for a 15 kg patient?

2 ml x 5 kg = 10 ml/hr.

p.6
Electrolyte Concentrations

What is the Na+ concentration in 3% Saline?

513 mEq/L.

p.18
Fluid Therapy in Surgery

What is the anticipated surgical fluid loss for a lap bowel resection?

Typically estimated at 5-10 ml/kg/hour, depending on the procedure.

p.5
Fluid Therapy in Surgery

What is the composition of D5W?

5% dextrose in water.

p.28
Estimating Blood Loss

How much would an 80 kg patient's Hgb/HCT increase after receiving 400 ml of PRBCs?

Approximately 1 g/dL for hemoglobin and about 3% for hematocrit.

p.25
Estimating Blood Loss

What is the lowest allowable hematocrit in this scenario?

28%.

p.29
Transfusion Guidelines and Effects

What is the expected increase in hematocrit from a 10 mL/kg transfusion of PRBC?

~10%.

p.1
Electrolyte Concentrations

What is the intracellular concentration of sodium (Na+)?

10 mEq/L.

p.1
Electrolyte Concentrations

Where is potassium (K+) primarily concentrated?

Intracellularly.

p.26
Estimating Blood Loss

What is the calculated maximum allowable blood loss (ABL) for the scenario?

1400 ml.

p.24
Estimating Blood Loss

How can the weight of sponges be used to estimate blood loss?

By weighing soaked sponges and subtracting the dry weight; 1 gram equals 1 milliliter of blood.

p.14
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 15 kg patient?

Approximately 1,200 mL per day.

p.21
Fluid Therapy in Surgery

How much fluid is administered in the first hour of surgery?

600 ml.

p.21
Fluid Therapy in Surgery

What is the total fluid administered in the third hour of surgery?

300 ml.

p.35
Fluid Therapy in Surgery

What is the age and gender of the patient?

70-year-old male.

p.35
Estimating Blood Loss

What are the hemoglobin and hematocrit levels preoperatively?

H/H: 10/30.

p.8
Estimating Blood Loss

Which option provides the most adequate response to an EBL of 500 mL?

D. None of the above.

p.36
Enhanced Recovery After Surgery (ERAS)

What is one key component of ERAS protocols?

Optimizing nutrition before and after surgery.

p.18
Fluid Therapy in Surgery

How do you calculate the fluid deficit for a patient NPO for 8 hours?

Fluid deficit = hourly maintenance rate x number of fasting hours.

p.33
Estimating Blood Loss

What is the estimated blood volume of a 370 lb male that is 6'0” tall?

Approximately 8.5 liters.

p.10
Transfusion Guidelines and Effects

Which blood types are compatible with a patient who has AB+ blood type?

All of the above (A negative, B positive, O negative).

p.32
Estimating Blood Loss

What is the intervention for a hypotensive patient with a Stroke Volume Variation (SVV) of 10%?

Consider fluid resuscitation.

p.25
Estimating Blood Loss

What is the weight of the male in the scenario for calculating maximum allowable blood loss?

90 kg.

p.30
Blood Bank Practices

What happens to 2, 3 DPG levels in stored PRBCs over time?

Decreased.

p.30
Blood Bank Practices

What happens to pH levels in stored PRBCs over time?

Decreased.

p.27
Massive Transfusion Protocol

What is hyperkalemia and why can it occur during massive transfusion?

Elevated potassium levels, often due to the release of potassium from stored red blood cells.

p.24
Estimating Blood Loss

How can blood loss be estimated during surgery?

By measuring blood within suction canisters and soaked surgical sponges.

p.24
Estimating Blood Loss

What is the formula to calculate blood loss using sponge weight?

Soaked weight (g) - dry weight (g) = blood loss (mL).

p.20
Maintenance Fluid Calculations

How do you calculate hourly maintenance fluid for a 60 kg patient?

Using the 4-2-1 rule: 4 mL/kg for the first 10 kg, 2 mL/kg for the next 10 kg, and 1 mL/kg for each kg above 20 kg.

p.20
Estimating Blood Loss

How do you calculate anticipated surgical fluid loss?

Estimate based on the type of surgery and expected blood loss.

p.20
Fluid Therapy in Surgery

What is the total fluid volume for the first hour of surgery?

Hourly maintenance + fluid deficit + anticipated loss for the first hour.

p.21
Fluid Therapy in Surgery

What is the total fluid administered in the first four hours of surgery?

1180 ml, 880 ml, 880 ml, 580 ml.

p.37
Enhanced Recovery After Surgery (ERAS)

What is the goal for patients in the preoperative period of ERAS?

To arrive in the OR in a euvolemic state.

p.16
Maintenance Fluid Calculations

What is the maintenance fluid calculation for the remaining 40 kg of body weight for a 75 kg patient?

1 ml x 40 kg = 55 ml/hr.

p.8
Estimating Blood Loss

What volume of plasmalyte is suggested in the options?

1500 mL.

p.23
Estimating Blood Loss

What is the estimated blood loss from 3 soaked lap pads?

300 ml.

p.6
Electrolyte Concentrations

What type of solution is 3% Saline?

Hypertonic.

p.11
Electrolyte Concentrations

What may occur with the rapid correction of hyponatremia?

Osmotic demyelination syndrome.

p.12
Clinical Manifestations of Hypocalcemia

What is Trousseau's sign?

A clinical manifestation of hypocalcemia characterized by carpal spasm when a blood pressure cuff is inflated.

p.7
Impact of Hypermagnesemia on Anesthesia

What is the effect of hypermagnesemia on opioid requirements during anesthesia?

It reduces opioid requirements.

p.29
Transfusion Guidelines and Effects

How much hemoglobin can be increased with a 10 mL/kg transfusion of PRBC?

3 g/dL.

p.1
Electrolyte Concentrations

What is the extracellular concentration of sodium (Na+)?

145 mEq/L.

p.1
Electrolyte Concentrations

What is the intracellular concentration of potassium (K+)?

140 mEq/L.

p.24
Estimating Blood Loss

How much blood does a soaked 4x4 surgical sponge represent?

10 mL of blood.

p.19
Maintenance Fluid Calculations

How much fluid is administered in Hour 1 for the patient?

480 mL.

p.15
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 100 kg patient?

140 ml/hr.

p.31
Blood Bank Practices

What happens to pH levels in stored PRBCs over time?

Decreased (↓).

p.34
Fluid Therapy in Surgery

How long has the patient been NPO (nothing by mouth) before surgery?

12 hours.

p.37
Enhanced Recovery After Surgery (ERAS)

What type of fluids are allowed up to 2 hours prior to surgery?

Clear fluids, including carbohydrate drinks.

p.8
Estimating Blood Loss

What is the estimated blood loss (EBL) addressed in the options?

500 mL.

p.37
Enhanced Recovery After Surgery (ERAS)

What should be done early in the postoperative period regarding IV fluids and drains?

Early discharge of IV fluids, NG tube, and drains.

p.6
Electrolyte Concentrations

What is the osmolarity of Lactated Ringer's (LR)?

273 mOsm/L.

p.18
Fluid Therapy in Surgery

How do you create an hourly fluid plan for a 3-hour surgical case?

Calculate total maintenance, deficit, and anticipated loss, then distribute fluids evenly across the surgical hours.

p.13
Fluid Therapy in Surgery

What are the standard fluid replacement considerations in perioperative fluid therapy?

1. Normal losses (maintenance requirements), 2. Preexisting fluid deficits, 3. Surgical loss (not including blood loss).

p.32
Estimating Blood Loss

What is the intervention for a hypotensive patient with a Stroke Volume Variation (SVV) of 20%?

Consider administering vasopressors.

p.2
Electrolyte Concentrations

Why are electrolytes important?

They help regulate nerve and muscle function, hydrate the body, balance blood acidity and pressure, and help rebuild damaged tissue.

p.3
Electrolyte Concentrations

Which substance would not result in a decreased plasma potassium concentration?

D. None of the above.

p.3
Electrolyte Concentrations

What effect does epinephrine have on plasma potassium concentration?

It decreases plasma potassium concentration.

p.4
Fluid Therapy in Surgery

Which type of solution would result in increased cell volume?

B. Hypotonic

p.9
Estimating Blood Loss

What is the role of crystalloid in fluid replacement?

To restore intravascular volume.

p.14
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 100 kg patient?

Approximately 4,000 mL per day.

p.21
Fluid Therapy in Surgery

What is the total fluid deficit for a patient NPO for 12 hours?

1200 ml.

p.15
Maintenance Fluid Calculations

What is the maintenance rate for the remaining weight in a 60 kg patient?

1 ml x 40 kg = 40 ml/hr.

p.34
Fluid Therapy in Surgery

What is the age and weight of the patient?

30 years old and 70 kg.

p.16
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 75 kg?

115 ml/hr.

p.37
Enhanced Recovery After Surgery (ERAS)

What anesthesia consideration is suggested during the intraoperative period?

Consider regional anesthesia.

p.36
Enhanced Recovery After Surgery (ERAS)

How does ERAS benefit patients post-surgery?

By promoting faster recovery and shorter hospital stays.

p.23
Estimating Blood Loss

What is the total volume within the suction canister?

800 ml.

p.6
Electrolyte Concentrations

What is the glucose concentration in Lactated Ringer's (LR)?

50 g/L.

p.12
Clinical Manifestations of Hypocalcemia

What is Chvostek's sign?

A clinical manifestation of hypocalcemia where tapping on the facial nerve causes twitching of the facial muscles.

p.17
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 15 kg?

50 mL/hr.

p.2
Electrolyte Concentrations

Name some common electrolytes.

Sodium, potassium, calcium, magnesium, chloride, bicarbonate, and phosphate.

p.30
Blood Bank Practices

What happens to lactate levels in stored PRBCs over time?

Increased.

p.22
Estimating Blood Loss

What is the total estimated blood loss (EBL) calculation based on the provided data?

Total EBL = (15 soaked 4 x 4's + 3 soaked lap pads + 800 ml in suction + 200 ml irrigation).

p.4
Fluid Therapy in Surgery

What is a hydrotonic solution?

Hydrotonic is not a standard term in fluid therapy.

p.9
Estimating Blood Loss

Which option provides the correct fluid replacement for an EBL of 2000 mL?

A. 1200 mL crystalloid; 500 mL colloid; 500 mL PRBC.

p.19
Maintenance Fluid Calculations

What is the fluid deficit for an 80 kg patient NPO for 8 hours?

960 ml.

p.31
Blood Bank Practices

What happens to potassium levels in stored PRBCs over time?

Increased (↑).

p.34
Fluid Therapy in Surgery

What is the diagnosis for the patient in the case scenario?

Menorrhagia with abdominal pain.

p.15
Maintenance Fluid Calculations

How is the maintenance rate calculated for the remaining weight in a 100 kg patient?

1 ml x 80 kg = 80 ml/hr.

p.34
Estimating Blood Loss

What is the maximum allowable blood loss based on the lowest hematocrit?

Lowest hematocrit is 28%.

p.37
Enhanced Recovery After Surgery (ERAS)

What is the goal for the postoperative period in ERAS?

To promote early mobilization and discharge.

p.6
Electrolyte Concentrations

What type of solution is Normal Saline (NS)?

Isotonic.

p.23
Estimating Blood Loss

What is the remaining volume in the suction canister after accounting for irrigation?

600 ml (800 ml - 200 ml).

p.29
Transfusion Guidelines and Effects

What is the expected increase in hematocrit from administering 1 unit of PRBC?

~3%.

p.3
Electrolyte Concentrations

What effect does insulin have on plasma potassium concentration?

It decreases plasma potassium concentration.

p.27
Massive Transfusion Protocol

Why might hypocalcemia occur during massive transfusion?

Due to citrate in stored blood binding calcium.

p.26
Estimating Blood Loss

What is the preoperative hematocrit for the 90 kg male?

36%.

p.14
Maintenance Fluid Calculations

What is the maintenance fluid requirement for a 60 kg patient?

Approximately 2,400 mL per day.

p.15
Maintenance Fluid Calculations

How is the maintenance rate calculated for the first 10 kg of body weight?

4 ml x 10 kg = 40 ml/hr.

p.31
Blood Bank Practices

What happens to lactate levels in stored PRBCs over time?

Increased (↑).

p.31
Blood Bank Practices

What happens to ATP levels in stored PRBCs over time?

Decreased (↓).

p.35
Fluid Therapy in Surgery

What are the patient's medical history conditions?

Osteoporosis and hypertension (HTN).

p.16
Maintenance Fluid Calculations

What is the maintenance fluid calculation for the next 10 kg of body weight for a 75 kg patient?

2 ml x 10 kg = 20 ml/hr.

p.36
Enhanced Recovery After Surgery (ERAS)

What does ERAS aim to minimize during the surgical recovery process?

Pain, stress, and complications.

p.23
Estimating Blood Loss

How much blood loss is estimated from 15 soaked 4 x 4's?

150 ml.

p.6
Electrolyte Concentrations

What is the Cl- concentration in D5 ½ NS?

77 mEq/L.

p.35
Fluid Therapy in Surgery

What surgical procedure is planned for the patient?

Total hip arthroplasty.

p.16
Maintenance Fluid Calculations

How is the maintenance fluid calculated for the first 10 kg of body weight?

4 ml x 10 kg = 40 ml/hr.

p.16
Maintenance Fluid Calculations

What is the maintenance fluid rate for a patient weighing 15 kg?

50 ml/hr.

p.36
Enhanced Recovery After Surgery (ERAS)

What type of approach does ERAS utilize?

A multidisciplinary approach involving various healthcare professionals.

p.18
Fluid Therapy in Surgery

What is the formula to calculate hourly maintenance fluid for an 80 kg patient?

Using the 4-2-1 rule: 4 ml/kg for the first 10 kg, 2 ml/kg for the next 10 kg, and 1 ml/kg for the remaining weight.

p.18
Fluid Therapy in Surgery

What is the total fluid requirement for an 80 kg patient over 3 hours?

Total fluid = maintenance + deficit + anticipated loss over 3 hours.

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