What is the first sensation to return during nerve recovery?
Pain is the first sensation to return.
What are common symptoms to ask about in cases of acute nerve injuries?
Numbness, paresthesia, or muscle weakness in the related area.
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p.4
Assessment of Nerve Recovery

What is the first sensation to return during nerve recovery?

Pain is the first sensation to return.

p.3
Clinical Features of Nerve Injuries

What are common symptoms to ask about in cases of acute nerve injuries?

Numbness, paresthesia, or muscle weakness in the related area.

p.4
Assessment of Nerve Recovery

What does MRI confirm in the context of nerve injuries?

MRI confirms the diagnosis of nerve injury.

p.6
Upper Limb Nerve Injuries

What is the level of a low lesion in radial nerve injuries?

Elbow or upper forearm.

p.9
Lower Limb Nerve Injuries

What are the common causes of sciatic nerve injury?

Traction lesions (traumatic hip dislocations and with pelvic fractures) and iatrogenic lesions (posterior approach in total hip replacement).

p.7
Clinical Features of Nerve Injuries

What are the clinical features of low ulnar nerve lesions?

Numbness of the ulnar one and a half fingers, claw hand deformity, weak finger abduction and thumb adduction, hypothenar and interosseous wasting, positive Froment’s sign.

p.2
Types of Nerve Injuries

What is a neuroma?

A painful fibrous tissue mass around the nerve ending formed by regenerating axons, Schwann cells, and fibroblasts.

p.7
Clinical Features of Nerve Injuries

What is the explanation for the difference in claw hand deformity between low and high ulnar nerve lesions?

In low lesions, the flexor digitorum profundus is working and causes flexion, leading to claw hand. In high lesions, both muscles are affected, resulting in less clawing.

p.6
Treatment and Management of Nerve Injuries

What is the recommended treatment if there is no recovery in radial nerve injuries?

Tendon transfer or arthrodesis if tendon transfer is not available.

p.3
Seddon's Classification of Nerve Injury

What is the characteristic of a fourth-degree nerve injury (neurotmesis 1)?

Only the epineurium is intact, severe internal damage, unlikely recovery, requiring excision and repair or grafting.

p.2
Seddon's Classification of Nerve Injury

What is Neurapraxia according to Seddon's Classification?

A reversible physiological nerve conduction block with loss of sensation and muscle power, followed by spontaneous recovery.

p.2
Clinical Features of Nerve Injuries

What are some examples of conditions that can cause Neurapraxia?

Crutch palsy, Saturday night palsy, tourniquet palsy, compartment syndrome, carpal tunnel syndrome, distal humerus fracture, and posterior hip dislocation.

p.7
Upper Limb Nerve Injuries

What are common causes of high ulnar nerve lesions?

Elbow fractures or dislocations.

p.8
Upper Limb Nerve Injuries

Where are high lesions of the median nerve most commonly located?

High up in the forearm.

p.1
Schwann Cells and Oligodendrocytes

What cells are responsible for the myelination of axons in the CNS?

Oligodendrocytes.

p.4
Assessment of Nerve Recovery

Which type of recovery is slower, motor or sensory?

Motor recovery is slower than sensory recovery.

p.2
Schwann Cells and Oligodendrocytes

What is Wallerian degeneration?

A process where axons are still intact but there is a dent in the myelin sheath/Schwann cells, with no damage to the nerve.

p.6
Clinical Features of Nerve Injuries

What clinical feature is preserved in low lesions of the radial nerve?

Wrist extension.

p.9
Lower Limb Nerve Injuries

What is a common peroneal nerve injury often associated with?

Damage at the level of the fibular neck.

p.6
Clinical Features of Nerve Injuries

What additional clinical feature is present in very high lesions of the radial nerve?

Paralysis of the triceps (loss of elbow extension) and absence of the triceps reflex.

p.5
Peripheral Nerve Anatomy

From which part of the brachial plexus does the axillary nerve arise?

The posterior cord.

p.8
Clinical Features of Nerve Injuries

What is the 'OK' sign and what does it indicate?

A positive 'OK' sign indicates high lesions of the median nerve.

p.1
Peripheral Nerve Anatomy

What encloses the groups of fascicles that make up a nerve trunk?

Epineurium.

p.1
Peripheral Nerve Anatomy

What is the role of the epineurium in areas where the nerve is subjected to movement and traction?

It is particularly strong to provide protection.

p.1
Types of Nerve Injuries

What are the common causes of nerve injuries?

Ischemia, compression, traction, laceration, or burning.

p.1
Transient Ischemia Pathology

What is transient ischemia and what are its initial symptoms?

Transient ischemia is caused by acute nerve compression, leading to numbness and tingling within 15 minutes.

p.4
Assessment of Nerve Recovery

What does two-point discrimination measure?

It measures innervation density.

p.3
Clinical Features of Nerve Injuries

What should be examined for in cases of acute nerve injuries?

Signs of abnormal posture (wrist/foot drop, claw hand, high-stepping gait), weakness, and changes in sensibility.

p.2
Treatment and Management of Nerve Injuries

How long should a tourniquet be applied to avoid nerve damage?

No more than 2-2:30 hours; if needed longer, remove it every 2 hours and reapply after 1 hour.

p.6
Upper Limb Nerve Injuries

What is the level of a high lesion in radial nerve injuries?

Humerus (around spiral groove).

p.7
Upper Limb Nerve Injuries

What are common causes of low ulnar nerve lesions?

Cuts on shattered glass or injury at the level of the forearm due to compression.

p.6
Upper Limb Nerve Injuries

What is the level of a very high lesion in radial nerve injuries?

Axilla or shoulder.

p.7
Assessment of Nerve Recovery

What is a positive Froment’s sign?

Inability to hold a paper using the thumb, compensating by using flexor pollicis longus due to loss of thumb adductor pollicis.

p.6
Treatment and Management of Nerve Injuries

What is the recommended treatment for open injuries of the radial nerve?

Nerve exploration and primary repair or grafting as soon as possible.

p.7
Upper Limb Nerve Injuries

What is ulnar neuritis (cubital tunnel syndrome)?

Compression or entrapment of the nerve in the medial epicondylar (cubital) tunnel.

p.1
Peripheral Nerve Anatomy

What is the connective tissue stocking that covers the axon outside the Schwann cell membrane?

Endoneurium.

p.4
Assessment of Nerve Recovery

What is Tinel’s Sign and when is it positive?

Tinel’s Sign is a test where peripheral tingling (paresthesia) or dysesthesia occurs upon percussing over the nerve. It is positive in axonotmesis and negative in neurapraxia.

p.3
Seddon's Classification of Nerve Injury

What is the characteristic of a third-degree nerve injury (axonotmesis)?

Disruption of the endoneurium with intact perineurium, good chances of axon regeneration but limited by fibrosis and crossed connections.

p.2
Types of Nerve Injuries

What is the most severe form of nerve injury involving the whole tissue and axonal disruption?

Neurotmesis, such as a knife cut of the forearm leading to drop wrist.

p.6
Types of Nerve Injuries

What injuries can cause high lesions of the radial nerve?

Fractures of the humerus or prolonged tourniquet pressure.

p.2
Seddon's Classification of Nerve Injury

What is Axonotmesis?

A more severe form of nerve injury involving axonal interruption, with loss of conduction but the nerve is in continuity.

p.9
Lower Limb Nerve Injuries

What are the clinical features of a tibial nerve injury?

Inability to plantar-flex the ankle or toes, absent sensation over the sole of the foot and part of the calf, and minimal clawing due to involvement of both long flexors and intrinsic muscles.

p.8
Upper Limb Nerve Injuries

What are common causes of high lesions of the median nerve?

Forearm fractures or elbow dislocation.

p.1
Peripheral Nerve Anatomy

What are the main components of a neuron?

Axon covered by myelin and Schwann cells.

p.8
Clinical Features of Nerve Injuries

What is the 'Pucker sign' and what does it indicate?

A positive 'Pucker sign' indicates high lesions of the median nerve.

p.1
Transient Ischemia Pathology

What is the least severe type of peripheral nerve injury?

Transient ischemia, as it involves no damage to the myelin.

p.4
Types of Nerve Injuries

What is the difference in recovery chances between low energy and high energy injuries?

Low energy injuries have a high chance of recovery, while high energy injuries (like MVA or fall from height) are not a good sign for the patient.

p.3
Seddon's Classification of Nerve Injury

What is the characteristic of a first-degree nerve injury (neurapraxia)?

Transient ischemia and neurapraxia, which is reversible.

p.2
Seddon's Classification of Nerve Injury

What causes Neurapraxia?

Mechanical pressure causing segmental demyelination, with the axon itself still intact.

p.8
Upper Limb Nerve Injuries

What are common causes of low lesions of the median nerve?

Cuts in front of the wrist or by carpal, lunate dislocations.

p.9
Lower Limb Nerve Injuries

What are the common causes of common peroneal nerve injury?

Severe traction when the knee is forced into varus, fractures around the knee, operative correction of gross valgus deformities, pressure from a splint or plaster cast, and lying with the leg externally rotated.

p.6
Types of Nerve Injuries

What injuries can cause very high lesions of the radial nerve?

Trauma or operations around the shoulder, chronic compression in the axilla (Saturday night palsy or crutch palsy).

p.2
Seddon's Classification of Nerve Injury

What is Neurotmesis?

The division of the nerve trunk, often due to high energy trauma, where regenerating axons cannot reach the end organ, leading to permanent dysfunction.

p.7
Clinical Features of Nerve Injuries

Why is the hand not markedly deformed in high ulnar nerve lesions?

Because the ulnar half of FDP (Flexor Digitorum Profundus) is paralyzed, causing less clawing of the fingers.

p.6
Treatment and Management of Nerve Injuries

What is the recommended treatment for closed injuries of the radial nerve?

Observation, splinting, physiotherapy, and sending the patient for EMG/NCS.

p.1
Transient Ischemia Pathology

What happens after 30 minutes of transient ischemia?

Loss of pain sensibility.

p.4
Assessment of Nerve Recovery

When are electromyography (EMG) and nerve conduction studies (NCS) typically performed?

Usually after 6 weeks, then at 3 months, 6 months, and 12 months.

p.3
Seddon's Classification of Nerve Injury

What is the characteristic of a second-degree nerve injury (axonotmesis)?

Axonal degeneration with preserved endoneurium, allowing for complete or near-complete recovery without intervention.

p.3
Seddon's Classification of Nerve Injury

What is the characteristic of a fifth-degree nerve injury (neurotmesis)?

The nerve is divided and the epineurium is injured, requiring repair.

p.8
Upper Limb Nerve Injuries

Where are low lesions of the median nerve most commonly located?

Near the wrist.

p.9
Lower Limb Nerve Injuries

What are the clinical features of a common peroneal nerve injury?

Foot-drop (inability to dorsiflex or evert the foot), high-stepping gait, and loss of sensation over the front and outer half of the leg and the dorsum of the foot.

p.2
Seddon's Classification of Nerve Injury

What happens during Axonotmesis?

Wallerian degeneration occurs distal to the lesion, and axonal regeneration starts within hours at a speed of 1-2 mm per day.

p.8
Clinical Features of Nerve Injuries

What additional muscles are paralyzed in high lesions of the median nerve compared to low lesions?

The long flexors to the thumb, index and middle fingers, the radial wrist flexors, the forearm pronator muscles.

p.5
Peripheral Nerve Anatomy

Which muscles are supplied by the axillary nerve?

Teres minor and deltoid muscle.

p.7
Upper Limb Nerve Injuries

What can cause severe valgus deformity of the elbow or prolonged pressure on the elbows?

Prolonged pressure on the elbows in anesthetized or bedridden patients.

p.8
Assessment of Nerve Recovery

What is the most sensitive clinical test for median nerve injury?

Durkan test (carpal compression test).

p.5
Peripheral Nerve Anatomy

What is a critical anatomical consideration during a deltoid splitting approach?

Avoiding injury to the anterior branch of the axillary nerve, which curls around the surgical neck of the humerus at 5 cm below the tip of the acromion.

p.5
Assessment of Nerve Recovery

How can you assess for axillary nerve injury?

Compare the shoulder contour of both sides.

p.4
Assessment of Nerve Recovery

What clinical tests are used to follow up nerve recovery?

Tests of muscle power and sensitivity to light touch and pin-prick.

p.4
Assessment of Nerve Recovery

What is the purpose of the monofilament assessment?

To check if the patient has a good degree of nerve sensitivity.

p.4
Assessment of Nerve Recovery

What is the significance of denervation potentials in EMG/NCS?

Denervation potentials appear by the third week, indicating nerve injury.

p.6
Types of Nerve Injuries

What injuries can cause low lesions of the radial nerve?

Fractures or dislocations at the elbow and iatrogenic lesions of the posterior interosseous nerve.

p.9
Lower Limb Nerve Injuries

What are the clinical features of a complete sciatic nerve lesion at the hip?

Paralysis of the hamstrings and all muscles below the knee, absent ankle jerk, loss of sensation below the knee except on the medial side of the leg, foot-drop, and high-stepping gait.

p.6
Clinical Features of Nerve Injuries

What is a common clinical feature of high lesions of the radial nerve?

Wrist drop.

p.8
Clinical Features of Nerve Injuries

What are the clinical features of low lesions of the median nerve?

Unable to abduct the thumb, loss of thumb opposition, sensation loss over the radial three and a half digits, thenar eminence wasting and trophic changes, carpal tunnel syndrome.

p.1
Schwann Cells and Oligodendrocytes

What cells are responsible for the myelination of axons in the PNS?

Schwann cells.

p.8
Clinical Features of Nerve Injuries

What is the 'pointing index sign' associated with?

High lesions of the median nerve.

p.5
Peripheral Nerve Anatomy

What is the function of the deltoid muscle?

Abduction of the shoulder.

p.1
Peripheral Nerve Anatomy

What separates axons into bundles (fascicles) in a nerve?

Perineurium.

p.1
Peripheral Nerve Anatomy

What type of blood supply does the epineurium have?

It is richly supplied by blood vessels that run longitudinally.

p.5
Peripheral Nerve Anatomy

What area of skin does the axillary nerve supply?

A patch of skin over the deltoid muscle at the proximal lateral arm.

p.8
Upper Limb Nerve Injuries

What are the characteristics of isolated anterior interosseous nerve lesions?

Similar to high lesions but without any sensory loss, usually caused by brachial neuritis (Parsonage–Turner syndrome).

p.1
Transient Ischemia Pathology

What is the sequence of symptoms in transient ischemia?

Numbness and tingling within 15 minutes, loss of pain sensibility after 30 minutes, muscle weakness after 45 minutes.

p.7
Upper Limb Nerve Injuries

What is Guyon’s Canal Syndrome?

Entrapment of the ulnar nerve as it passes through Guyon’s canal at the ulnar border of the wrist, commonly caused by a ganglion or ulnar artery aneurysm.

p.5
Clinical Features of Nerve Injuries

What are the clinical features of axillary nerve injury?

Shoulder weakness, rapid deltoid wasting, numbness over the deltoid, and a high recovery rate with 80% of cases recovering spontaneously.

p.7
Assessment of Nerve Recovery

How is Guyon’s Canal Syndrome diagnosed?

MRI will diagnose the ganglion, which is the most common cause.

p.5
Types of Nerve Injuries

What are common causes of axillary nerve injuries?

Shoulder dislocation or fractures of the humeral neck, and lateral deltoid-splitting incisions.

p.1
Transient Ischemia Pathology

What occurs after the relief of compression in transient ischemia?

Intense paresthesia for 5 minutes, feeling restored within 30 seconds, and full muscle power after about 10 minutes.

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