CSF testing in LGI1 encephalitis usually shows normal ___ and protein levels.
white blood cell counts
The HLA-DRB1*07:01 allele is found in about ___% of patients with LGI1 encephalitis.
90
1/18
Diagnostic Investigations for LGI1 Encephalitis

CSF testing in LGI1 encephalitis usually shows normal ___ and protein levels.

white blood cell counts

Diagnostic Investigations for LGI1 Encephalitis

The HLA-DRB1*07:01 allele is found in about ___% of patients with LGI1 encephalitis.

90

MRI and PET Scan Findings

MRI can show hyperintensity in the ___ and amygdala on T2-weighted imaging.

hippocampus

NMDA Receptor Encephalitis Overview

Ovarian teratomas are found in about ___% of affected women aged 18-35 with NMDA receptor encephalitis.

30

Faciobrachial Dystonic Seizures (FBDS)

FBDS seizures are ___ and stereotyped.

short-lived

MRI and PET Scan Findings

PET scans can show abnormalities in the ___ temporal lobe in patients with normal MRI.

mesial

NMDA Receptor Encephalitis Overview

NMDA receptor encephalitis antibodies target the ___ subunit of the NMDA receptor.

NR1

Pathognomonic Features of FBDS

FBDS is highly specific to ___ antibodies.

LGI1

Importance of Early Treatment and Immunotherapy

Cognitive impairment in LGI1 encephalitis develops after seizures and can be prevented with early ___.

immunotherapy

EEG and CSF Testing Results

EEG shows seizure activity and mildly ___ background rhythms.

slowed

Behavioral Changes in Patients

Behavioral changes in LGI1 encephalitis include alterations in ___ and mood changes.

personality

Faciobrachial Dystonic Seizures (FBDS)

Faciobrachial Dystonic Seizures (FBDS) are not associated with the pain of ___ spasms.

tonic

Faciobrachial Dystonic Seizures (FBDS)

FBDS can occur ___ of times per day and may be the sole feature of the disease.

hundreds

Cognitive Impairment and Amnesia

Patients with LGI1 encephalitis often develop severe ___ amnesia due to bilateral hippocampal involvement.

anterograde

Diagnostic Investigations for LGI1 Encephalitis

Low serum ___ levels are found in about half of the patients with LGI1 encephalitis.

sodium

NMDA Receptor Encephalitis Overview

LGI1 encephalitis typically affects older ___ and rarely involves tumors.

males

Disease Progression in LGI1 Encephalitis

In the early phase of disease progression, ___ are typically the only symptom.

seizures

NMDA Receptor Encephalitis Overview

NMDA receptor encephalitis is more common in ___ (3:1 ratio).

females

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