To illustrate the proportion of a population that responds to different doses of a drug.
Lithium's therapeutic index is crucial for monitoring its effectiveness and avoiding toxicity.
The relationship between the dose of a drug and the occurrence of a certain response in a large group of people.
The dose at which 50 percent of the population responds to the drug in a specified manner.
A resource for drug information and medical references.
Cumulative or quantal responses.
TI = TD50 / ED50.
The drug is safer.
To check for potential drug interactions.
The relationship between the dose of a drug and a specific response.
The dose at which 50 percent of the population shows the adverse effect.
Information related to drug approvals, safety, and regulations.
Theophylline has a narrow therapeutic index, requiring careful monitoring.
The therapeutic index of Acetaminophen indicates its safety margin between effective and toxic doses.
A lower dose.
It is used as an indicator of a drug's safety.
No, potency is not related to the therapeutic index.
Warfarin is primarily used as an anticoagulant to prevent blood clots.
No, potency is not related to maximal efficacy.
Digoxin has a narrow therapeutic index, meaning the difference between effective and toxic doses is small.
Valium is primarily used as an anxiolytic and muscle relaxant.
Valium has a therapeutic index that reflects its effectiveness and potential toxicity.
Information on drug interactions and safety.
The minimum dose of a drug that produces a measurable effect.
Lithium has a narrow therapeutic index, requiring regular blood level monitoring.
General health information, including drug-related content.
The amount of drug needed to produce a specific effect.
The point at which increasing the dose of a drug does not increase its effect.
It represents the distribution of responses to different doses of a drug in a population.
Acetaminophen has a relatively wide therapeutic index but can be toxic in overdose.