What is the formula of cholesterol?
C27H46O.
What is a liposome?
A liposome is a spherical vesicle composed of lipid bilayers, often used in drug delivery.
1/371
p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of cholesterol?

C27H46O.

p.21
Biological Functions of Iron

What is a liposome?

A liposome is a spherical vesicle composed of lipid bilayers, often used in drug delivery.

p.20
Physiological Importance of Amino Acids and Proteins

Give examples of some plasma enzymes that perform physiological functions in the blood.

Examples include alkaline phosphatase, lactate dehydrogenase, and creatine kinase.

p.4
Physiological Importance of Amino Acids and Proteins

What is the structure of histidine?

Histidine contains an imidazole ring.

p.27
Physiological Importance of Amino Acids and Proteins

What is a stop codon?

A nucleotide triplet that signals the termination of protein synthesis.

p.27
Physiological Importance of Amino Acids and Proteins

What is the initiation of translation?

The process where ribosomes assemble around the mRNA to start protein synthesis.

p.15
Biological Functions of Iron

What is the medical function of 5-methyluracil?

5-methyluracil (thymine) is involved in DNA synthesis and stability.

p.27
Physiological Importance of Amino Acids and Proteins

What is a point mutation?

A change in a single nucleotide in the DNA sequence.

p.9
Role of EDTA and Desferoxamine

What is the structure and function of chondroitin sulfate?

Chondroitin sulfate is a glycosaminoglycan (GAG) that provides structural support and elasticity in cartilage.

p.27
Physiological Importance of Amino Acids and Proteins

What are the properties of the genetic code?

It is universal, redundant, and unambiguous.

p.8
Physiological Importance of Amino Acids and Proteins

What is the structure and function of starch?

Starch is a polysaccharide made up of glucose units, serving as an energy storage molecule in plants.

p.22
Physiological Importance of Amino Acids and Proteins

How can fatty acids influence fluidity in membranes?

Unsaturated fatty acids increase fluidity, while saturated fatty acids decrease it.

p.26
Maturation of mRNA

What is the function of the CAAT sequence?

It enhances the transcription of genes.

p.9
Role of EDTA and Desferoxamine

What is the difference between proteoglycans and glycoproteins?

Proteoglycans are primarily composed of glycosaminoglycans, while glycoproteins have a higher proportion of protein.

p.4
Physiological Importance of Amino Acids and Proteins

What is the formula of the dipeptide cysteinyl-alanine?

C5H10N2O3S.

p.4
Physiological Importance of Amino Acids and Proteins

Name a cyclic amino acid.

Proline.

p.12
Physiological Importance of Amino Acids and Proteins

What is the structure and function of phosphatidylcholine?

Phosphatidylcholine is a phospholipid that plays a key role in cell membrane structure and function.

p.4
Physiological Importance of Amino Acids and Proteins

What is the formation of a peptide bond between an acidic and a branched chain amino acid?

The reaction involves the carboxyl group of the acidic amino acid and the amino group of the branched chain amino acid, releasing water.

p.4
Physiological Importance of Amino Acids and Proteins

Describe the structure and function of insulin.

Insulin is a peptide hormone composed of two chains (A and B) linked by disulfide bonds; it regulates glucose levels in the blood.

p.11
Physiological Importance of Amino Acids and Proteins

What is the formula for phosphatidylserine?

C18H37N2O8P.

p.11
Physiological Importance of Amino Acids and Proteins

What is phosphatidylethanolamine's structure and function?

It is a phospholipid that plays a role in membrane structure and cell signaling.

p.14
Physiological Importance of Amino Acids and Proteins

What is the structure and function of phosphatidylcholine?

Phosphatidylcholine is a phospholipid composed of a glycerol backbone, two fatty acid tails, a phosphate group, and a choline molecule. It functions as a major component of cell membranes.

p.1
Gibbs Free Energy Equation

What is the mathematical equation for the change of Gibbs free energy?

∆G = ∆H - T∆S

p.14
Physiological Importance of Amino Acids and Proteins

What are the components of cerebrocides?

Cerebrocides are composed of a ceramide and a carbohydrate, typically a monosaccharide or disaccharide.

p.8
Physiological Importance of Amino Acids and Proteins

What is lactose and what is its function?

Lactose is a disaccharide composed of glucose and galactose, functioning as a sugar found in milk.

p.12
Physiological Importance of Amino Acids and Proteins

What is cardiolipin?

Cardiolipin is a phospholipid that is important for mitochondrial function.

p.12
Physiological Importance of Amino Acids and Proteins

What is the function of ethanolamine?

Ethanolamine is involved in the synthesis of phospholipids and cell membranes.

p.12
Physiological Importance of Amino Acids and Proteins

What are prostaglandins?

Prostaglandins are lipid compounds that have diverse hormone-like effects in the body.

p.27
Physiological Importance of Amino Acids and Proteins

What does tRNA bind amino acids to?

The corresponding codon on the mRNA during translation.

p.1
Biological Functions of Iron

What is a biological function of iron?

It is a part of hemoglobin, transferring oxygen in blood.

p.18
Biological Functions of Iron

What is the biological function of NAD+?

NAD+ acts as a coenzyme in redox reactions, facilitating the transfer of electrons.

p.27
Physiological Importance of Amino Acids and Proteins

What is the predominant secondary structure of DNA?

The double helix, characterized by two strands wound around each other.

p.8
Physiological Importance of Amino Acids and Proteins

What bonds are found in glycogen and what is its function?

Glycogen contains alpha-1,4 and alpha-1,6 glycosidic bonds, functioning as energy storage in animals.

p.18
Biological Functions of Iron

What is ubiquinone?

Ubiquinone, also known as coenzyme Q, is a lipid-soluble molecule that plays a key role in the electron transport chain.

p.14
Physiological Importance of Amino Acids and Proteins

What is the formula of phosphatidylcholine and its function?

The formula is C44H84NO8P, and its function is to maintain cell membrane integrity and fluidity.

p.6
Physiological Importance of Amino Acids and Proteins

What is decarboxylation of amino acids?

The removal of a carboxyl group from an amino acid, resulting in the formation of an amine.

p.13
Physiological Importance of Amino Acids and Proteins

What is cardiolipin?

A type of phospholipid found in the inner mitochondrial membrane.

p.7
Physiological Importance of Amino Acids and Proteins

Which of the following compounds exhibit optical isomerism?

All of them (Fructose, Glycine, Palmitic acid).

p.11
Physiological Importance of Amino Acids and Proteins

What is the formula of palmitic acid?

C16H32O2.

p.13
Physiological Importance of Amino Acids and Proteins

What is a glycolipid?

A lipid with a carbohydrate attached, important for cell recognition.

p.22
Physiological Importance of Amino Acids and Proteins

Which non-covalent forces are important in biological membranes?

Hydrophobic interactions, ionic bonds, and hydrogen bonds.

p.1
Molar Concentration Calculations

What is the pH of a 0.1 mmol/l solution?

pH = 1

p.5
Physiological Importance of Amino Acids and Proteins

Where is the peptide bond located between amino acids?

The peptide bond is formed between the carboxyl group of one amino acid and the amino group of another.

p.16
Biological Functions of Iron

What is the formula of glyceraldehyde 3-phosphate?

C3H7O6P.

p.29
Gene manipulation

How can DNA fragments be separated?

By gel electrophoresis.

p.30
Methods of Colloid Separation

What is PCR?

Polymerase Chain Reaction, a method used to amplify DNA.

p.5
Physiological Importance of Amino Acids and Proteins

What is the physiological importance of peptides?

Peptides play roles in signaling, hormone regulation, and immune responses.

p.19
Physiological Importance of Amino Acids and Proteins

What is phosphorylation of enzymes?

A process that involves the addition of a phosphate group to an enzyme, which can alter its activity.

p.28
Biological Functions of Iron

What is glyceraldehyde 3-phosphate?

Glyceraldehyde 3-phosphate is a three-carbon sugar involved in glycolysis and the Calvin cycle.

p.14
Physiological Importance of Amino Acids and Proteins

Name three unsaturated fatty acids and draw one of them.

Three unsaturated fatty acids are oleic acid, linoleic acid, and alpha-linolenic acid.

p.29
Gene manipulation

What bonds are found in DNA?

Hydrogen bonds between nitrogenous bases and phosphodiester bonds in the backbone.

p.20
Physiological Importance of Amino Acids and Proteins

What is a holoenzyme?

A holoenzyme is the active form of an enzyme that includes its cofactor.

p.4
Physiological Importance of Amino Acids and Proteins

Is tyrosine an essential amino acid?

No, tyrosine is a non-essential amino acid.

p.13
Physiological Importance of Amino Acids and Proteins

What is the precursor of eicosanoids?

Arachidonic acid.

p.27
Physiological Importance of Amino Acids and Proteins

What is the regulation of gene expression in eukaryotes?

The control of the timing and amount of gene expression at various levels.

p.29
Gene manipulation

What is sheared DNA?

DNA that has been fragmented into smaller pieces.

p.16
Biological Functions of Iron

What type of bond exists between ribose and the nitrogenous base in nucleotides?

A glycosidic bond.

p.14
Physiological Importance of Amino Acids and Proteins

What is sphingomyelin?

Sphingomyelin is a type of sphingolipid that contains a sphingosine backbone, a fatty acid, and a phosphate group linked to choline.

p.6
Physiological Importance of Amino Acids and Proteins

What are the different forms of secondary structure in proteins?

Alpha helices and beta sheets.

p.14
Physiological Importance of Amino Acids and Proteins

What are lipoproteins composed of?

Lipoproteins are composed of lipids (triglycerides and cholesterol) and proteins (apolipoproteins).

p.10
Physiological Importance of Amino Acids and Proteins

Which homopolysaccharide has alpha-glycosidic bonds?

Starch.

p.16
Biological Functions of Iron

Which nucleotide is involved in the synthesis of phospholipids?

CTP is involved in the synthesis of phospholipids.

p.15
Biological Functions of Iron

What is adenosine?

Adenosine is a nucleoside composed of adenine and ribose, playing a role in energy transfer and signaling.

p.1
Oncotic Pressure

What is an isotonic solution?

A solution that has the same osmotic pressure as blood plasma in humans.

p.14
Physiological Importance of Amino Acids and Proteins

What is the structure of cholesteryl stearate and its formula?

Cholesteryl stearate consists of a cholesterol molecule esterified with stearic acid, and its formula is C27H46O2.

p.19
Physiological Importance of Amino Acids and Proteins

What is stereospecificity?

The property of an enzyme to catalyze a reaction with a specific stereoisomer of a substrate.

p.25
Biological Functions of Iron

Name three chemical mutagens.

1. Alkylating agents 2. Base analogs 3. Intercalating agents.

p.13
Physiological Importance of Amino Acids and Proteins

What is a cerebroside?

A type of glycolipid that contains a single sugar moiety.

p.9
Physiological Importance of Amino Acids and Proteins

What are the components of lactose?

Glucose and galactose.

p.29
Gene manipulation

What enzyme is responsible for synthesizing mRNA and cDNA?

RNA polymerase.

p.29
Gene manipulation

What is the control site of flux in a reaction?

The regulatory site or allosteric site.

p.11
Physiological Importance of Amino Acids and Proteins

What is a ganglioside composed of?

A glycosphingolipid with one or more sialic acids.

p.11
Physiological Importance of Amino Acids and Proteins

Draw cholesterol.

Cholesterol is a sterol with a specific four-ring structure.

p.22
Physiological Importance of Amino Acids and Proteins

What are the two major classes of membrane proteins?

Integral proteins and peripheral proteins.

p.16
Biological Functions of Iron

What is the medical importance of 5-fluoro uracil?

5-fluoro uracil is used as a chemotherapy agent to inhibit thymidylate synthase, thus interfering with DNA synthesis in cancer cells.

p.26
Maturation of mRNA

What is the structure of the last nucleotide in the mRNA cap?

It is a modified guanine nucleotide (7-methylguanylate).

p.22
Methods of Colloid Separation

What regulates the mechanisms of ionic channel activity?

Voltage, ligands, and mechanical forces.

p.18
Biological Functions of Iron

What are isoenzymes?

Isoenzymes are different forms of an enzyme that catalyze the same reaction but differ in structure and kinetic properties.

p.21
Biological Functions of Iron

What is asymmetrical distribution by lipids in membranes?

It refers to the uneven distribution of different types of lipids between the inner and outer leaflets of the membrane.

p.8
Physiological Importance of Amino Acids and Proteins

Which type of bond links monomers in polysaccharides?

Glycosidic bonds link monomers in polysaccharides.

p.32
Biological Functions of Iron

What class of enzymes catalyzes the conversion of galactose to glucose?

Galactose-1-phosphate uridylyltransferase (or similar enzymes in the galactose metabolism pathway).

p.12
Physiological Importance of Amino Acids and Proteins

What is the structure of linolenic acid?

Linolenic acid is a polyunsaturated fatty acid with three double bonds.

p.3
Physiological Importance of Amino Acids and Proteins

What is the decarboxylation reaction of glutamic acid?

Glutamic acid loses a carboxyl group to form gamma-aminobutyric acid (GABA).

p.7
Physiological Importance of Amino Acids and Proteins

What is the product of the oxidation of glucose at carbon C-6?

The product is gluconic acid.

p.13
Physiological Importance of Amino Acids and Proteins

What are the main constituents of phospholipids?

Glycerol, fatty acids, phosphate group, and an alcohol.

p.22
Physiological Importance of Amino Acids and Proteins

What holds membrane proteins in place?

Non-covalent interactions and lipid bilayer structure.

p.22
Physiological Importance of Amino Acids and Proteins

What are the different classes of proteins in membranes?

Integral proteins and peripheral proteins; integral proteins span the membrane, while peripheral proteins are attached to the surface.

p.11
Physiological Importance of Amino Acids and Proteins

What is plasmalogen?

A type of phospholipid with a vinyl ether bond.

p.16
Biological Functions of Iron

What is the biological function of CTP?

CTP (cytidine triphosphate) is involved in the synthesis of RNA and acts as a substrate for the enzyme RNA polymerase.

p.26
Maturation of mRNA

What is the process of maturation of mRNA?

It involves capping, polyadenylation, and splicing.

p.6
Isoelectric Point Definition

What is the formula of valine when it is below the isoelectric point?

Valine exists in its cationic form.

p.28
Biological Functions of Iron

What is the complementary sequence of 5’ ACGTCA 3’?

3’ TGCACT 5’.

p.5
Physiological Importance of Amino Acids and Proteins

What is the physiological importance of amino acids?

Amino acids are essential for protein synthesis, neurotransmitter production, and metabolic pathways.

p.1
Molar Concentration Calculations

What is the final concentration of a sucrose solution after adding 120 ml of water to 40 ml of 1.6 mol/l sucrose?

0.533 mol/L.

p.29
Gene manipulation

What is the structure of DNA?

A double helix composed of nucleotides, with a sugar-phosphate backbone and nitrogenous bases.

p.28
Biological Functions of Iron

What is proteolysis?

Proteolysis is the process of breaking down proteins into smaller peptides or amino acids.

p.26
Maturation of mRNA

Where does RNA polymerase bind?

To the promoter region of DNA.

p.11
Physiological Importance of Amino Acids and Proteins

What are some examples of unsaturated fatty acids?

Examples include oleic acid, linoleic acid, and alpha-linolenic acid.

p.7
Physiological Importance of Amino Acids and Proteins

What is the structure of chondroitin sulfate and what is its function?

Chondroitin sulfate is a glycosaminoglycan that provides structural support in cartilage.

p.11
Physiological Importance of Amino Acids and Proteins

What is a constituent of sphingomyelin?

Sphingosine.

p.12
Physiological Importance of Amino Acids and Proteins

What is the structure of cholesterol?

Cholesterol has a complex ring structure with a hydroxyl group.

p.26
Maturation of mRNA

What is the role of promoters in eukaryotic cells?

They initiate transcription by providing a binding site for RNA polymerase.

p.26
Maturation of mRNA

What enzymes are responsible for RNA synthesis?

RNA polymerases.

p.5
Physiological Importance of Amino Acids and Proteins

What is the quaternary structure of proteins?

The quaternary structure refers to the arrangement of multiple polypeptide chains into a single functional unit.

p.28
Biological Functions of Iron

What are the different forms of DNA?

The main forms of DNA are A-DNA, B-DNA, and Z-DNA.

p.22
Physiological Importance of Amino Acids and Proteins

What is the movement of phospholipids in membranes?

Phospholipids can move laterally within the membrane and occasionally flip-flop between layers.

p.28
Biological Functions of Iron

What is the secondary structure of tRNA?

The secondary structure of tRNA is characterized by a cloverleaf shape formed by base pairing.

p.18
Biological Functions of Iron

Name at least two coenzymes that participate in oxidation-reduction reactions.

NAD+ and FAD.

p.15
Biological Functions of Iron

What is the biological function of 5-fluoro uracil?

5-fluoro uracil is an antimetabolite used in cancer treatment that inhibits thymidylate synthase, affecting DNA synthesis.

p.8
Physiological Importance of Amino Acids and Proteins

Glucose is oxidized to what?

Glucose is oxidized to produce carbon dioxide and water, releasing energy.

p.22
Physiological Importance of Amino Acids and Proteins

Where is GLUT 4 located and what is its function?

GLUT 4 is located in adipose tissue and muscle; it facilitates glucose uptake in response to insulin.

p.10
Physiological Importance of Amino Acids and Proteins

What are the anomers of mannose?

Alpha-mannose and beta-mannose.

p.15
Biological Functions of Iron

What is the medical function of S-adenosylmethionine (SAM)?

SAM is a methyl donor in methylation reactions and is involved in the synthesis of neurotransmitters.

p.25
Biological Functions of Iron

What is the function of DNA polymerase in DNA replication?

DNA polymerase synthesizes new DNA strands by adding nucleotides complementary to the template strand.

p.15
Biological Functions of Iron

Which interaction connects bases in DNA?

Hydrogen bonds connect the bases in DNA.

p.28
Biological Functions of Iron

How is gene expression regulated in eukaryotes?

Gene expression in eukaryotes is regulated at multiple levels, including transcription, RNA processing, and translation.

p.19
Physiological Importance of Amino Acids and Proteins

What is the biological role of pantothenic acid?

It is essential for the synthesis of coenzyme A, which is important in fatty acid metabolism.

p.25
Biological Functions of Iron

What are the uses of recombination of DNA?

Recombination of DNA is used in genetic engineering, gene therapy, and the production of recombinant proteins.

p.30
Methods of Colloid Separation

What is a vector?

A DNA molecule used to deliver genetic material into a cell.

p.21
Biological Functions of Iron

What factors affect membrane fluidity?

Temperature, lipid composition, and cholesterol content.

p.7
Physiological Importance of Amino Acids and Proteins

What is the structure of lactose and how are its components bonded?

Lactose is a disaccharide composed of glucose and galactose, bonded by a glycosidic linkage.

p.27
Physiological Importance of Amino Acids and Proteins

What is post-translational modification?

Chemical changes to a protein after its translation, affecting its function and activity.

p.3
Physiological Importance of Amino Acids and Proteins

What amino acid is important in the formation of nitric oxide (NO)?

Arginine.

p.3
Physiological Importance of Amino Acids and Proteins

Describe insulin and glucagon and what they are composed of.

Insulin is a peptide hormone composed of 51 amino acids, while glucagon is composed of 29 amino acids.

p.3
Physiological Importance of Amino Acids and Proteins

What noncovalent interactions occur between phenylalanine and leucine in a polypeptide chain?

Hydrophobic interactions.

p.28
Biological Functions of Iron

What is the secondary structure of DNA?

The secondary structure of DNA refers to its double helix formation, where two strands are coiled around each other.

p.1
Isoelectric Point Definition

What is the isoelectric point?

It is when a molecule has no net electric charge.

p.8
Physiological Importance of Amino Acids and Proteins

What is the structural formula of the sugar found in the blood?

The sugar found in the blood is glucose, which has the formula C6H12O6.

p.26
Maturation of mRNA

What is the difference between hnRNA and mRNA?

hnRNA is the precursor to mRNA and includes introns, while mRNA is the processed form that is translated into protein.

p.22
Methods of Colloid Separation

Describe transcellular, intracellular, and homocellular transport.

Transcellular transport moves substances across a cell, intracellular transport moves substances within a cell, and homocellular transport occurs between adjacent cells.

p.8
Physiological Importance of Amino Acids and Proteins

What is an optical isomer?

An optical isomer is a molecule that has the same molecular formula but differs in the spatial arrangement of atoms, resulting in non-superimposable mirror images.

p.1
Methods of Colloid Separation

What are the stabilizing factors of hydrophilic colloids?

Solvation and electrostatic interactions.

p.26
Maturation of mRNA

What is splicing?

The process of removing introns from hnRNA to produce mature mRNA.

p.2
Physiological Importance of Amino Acids and Proteins

What is the process of decarboxylation of serine?

Decarboxylation of serine involves the removal of a carboxyl group, resulting in the formation of ethanolamine.

p.21
Biological Functions of Iron

What is the biological function of biomembrane?

To serve as a barrier that regulates the movement of substances in and out of the cell.

p.5
Physiological Importance of Amino Acids and Proteins

What are the structures of phosphorylated amino acids?

Phosphorylated amino acids have a phosphate group attached to their side chains, altering their function.

p.6
Physiological Importance of Amino Acids and Proteins

Describe the bonds between the monomers in glycogen.

Glycogen is composed of alpha-1,4-glycosidic bonds with branching via alpha-1,6-glycosidic bonds.

p.5
Physiological Importance of Amino Acids and Proteins

What is phosphorylation?

Phosphorylation is the addition of a phosphate group to a molecule, often regulating protein function.

p.30
Methods of Colloid Separation

What are restriction endonucleases?

Enzymes that cut DNA at specific sequences, important for recombinant DNA technology.

p.20
Physiological Importance of Amino Acids and Proteins

What is the medical application of liposomes?

Liposomes are used as drug delivery systems to enhance the bioavailability of therapeutic agents.

p.29
Gene manipulation

What is DNA amplification?

The process of making multiple copies of a specific DNA segment.

p.3
Physiological Importance of Amino Acids and Proteins

What bonds are present in the tertiary structure of proteins?

Hydrogen bonds, ionic bonds, disulfide bridges, and hydrophobic interactions.

p.13
Physiological Importance of Amino Acids and Proteins

What is ceramide?

A lipid molecule composed of sphingosine and a fatty acid.

p.9
Physiological Importance of Amino Acids and Proteins

What does a homopolysaccharide consist of?

A homopolysaccharide consists of repeating units of the same monosaccharide.

p.9
Physiological Importance of Amino Acids and Proteins

What are homopolysaccharides with glycosidic bonds?

Homopolysaccharides are polysaccharides formed by glycosidic bonds between identical monosaccharides.

p.27
Physiological Importance of Amino Acids and Proteins

What is the difference between mRNA, tRNA, and rRNA?

mRNA carries genetic information, tRNA transfers amino acids, and rRNA forms the core of ribosome structure.

p.1
Molar Concentration Calculations

What is the molar concentration of a solution with 9 g of NaCl in 1000 ml?

0.15 mol/L (molecular weight of NaCl is 60 g/mol).

p.5
Physiological Importance of Amino Acids and Proteins

What is the reaction of decarboxylation of aspartic acid?

Aspartic acid loses a carboxyl group to form aspartamine, which functions as a neurotransmitter.

p.1
Molar Concentration Calculations

What is the pH of a buffer system with HCO3- = 0.3 mol/l, H2CO3 = 0.03 mol/l and pK = 6.3?

5.3 (calculated as 6.3 + log(0.3/0.03)).

p.29
Gene manipulation

What does denaturation of proteins affect?

The protein's structure and function.

p.5
Physiological Importance of Amino Acids and Proteins

What is the physiological importance of peptidase?

Peptidases are enzymes that break down peptides into amino acids, facilitating digestion and absorption.

p.29
Gene manipulation

What is restriction fragment length polymorphism (RFLP)?

A technique that exploits variations in homologous DNA sequences.

p.16
Biological Functions of Iron

What kind of weak noncovalent forces are responsible for base pairing in DNA?

Hydrogen bonds are responsible for base pairing in DNA.

p.26
Maturation of mRNA

What is the function of the mRNA cap?

It protects mRNA from degradation and assists in ribosome binding during translation.

p.2
Physiological Importance of Amino Acids and Proteins

Describe the quaternary structure of a protein.

The quaternary structure refers to the arrangement of multiple polypeptide chains into a single functional protein complex.

p.21
Biological Functions of Iron

What are the components of membrane lipids and their function?

Phospholipids, cholesterol, and glycolipids; they provide structure and fluidity to the membrane.

p.28
Biological Functions of Iron

What is shared DNA?

Shared DNA refers to genetic material that is common between different organisms or species.

p.15
Biological Functions of Iron

What is the function of deoxyriobose adenosine triphosphate (ATP)?

ATP serves as the primary energy carrier in cells.

p.23
Physiological Importance of Amino Acids and Proteins

What is Na+/K+ ATPase?

An enzyme that pumps sodium out of cells and potassium into cells, crucial for maintaining cellular ion balance.

p.25
Biological Functions of Iron

What removes the RNA primer during DNA replication?

DNA polymerase I removes the RNA primer.

p.25
Biological Functions of Iron

What is DNA ligase?

DNA ligase is an enzyme that joins Okazaki fragments and seals nicks in the DNA backbone.

p.23
Physiological Importance of Amino Acids and Proteins

What are homocellular, intracellular, and transcellular transport?

Homocellular transport is between similar cells, intracellular transport is within a cell, and transcellular transport is across a cell layer; examples include nutrient absorption.

p.30
Methods of Colloid Separation

What is a probe?

A labeled fragment of DNA or RNA used to detect specific sequences.

p.21
Biological Functions of Iron

What stabilizes the membranes of erythrocytes?

The presence of spectrin and other cytoskeletal proteins.

p.7
Physiological Importance of Amino Acids and Proteins

What are the structures of mannose and glucose?

Mannose and glucose are both six-carbon aldoses with specific structural formulas.

p.7
Physiological Importance of Amino Acids and Proteins

What is the reaction of glucose oxidation on carbon atom C-1 and what is the product?

The reaction produces gluconic acid when glucose is oxidized at C-1.

p.12
Physiological Importance of Amino Acids and Proteins

Name three unsaturated fatty acids and provide one formula.

Examples include oleic acid (C18H34O2), linoleic acid (C18H32O2), and linolenic acid (C18H30O2).

p.1
Fenton Reaction and Hydroxyl Radical Production

What is the Fenton reaction for hydroxyl radical production?

Fe3+ + H2O2 → Fe2+ + OH- + OH*

p.9
Role of EDTA and Desferoxamine

What are GAGs and their functions?

Glycosaminoglycans (GAGs) are long unbranched polysaccharides that provide structural support, lubrication, and hydration in tissues.

p.14
Physiological Importance of Amino Acids and Proteins

What is the formula for triacylglycerol?

C55H98O6.

p.29
Gene manipulation

What are the levels of regulation at the DNA level?

Transcriptional, post-transcriptional, translational, and post-translational regulation.

p.10
Physiological Importance of Amino Acids and Proteins

Which homopolysaccharide has beta-bonds?

Cellulose.

p.15
Biological Functions of Iron

What is the biological function of CTP?

CTP (cytidine triphosphate) is involved in the synthesis of RNA and acts as a substrate for RNA polymerase.

p.16
Biological Functions of Iron

What is the structure and function of cyclic GMP?

Cyclic GMP (cGMP) is a cyclic nucleotide that acts as a second messenger in various signaling pathways, regulating processes like vasodilation.

p.30
Methods of Colloid Separation

What is DNA fingerprinting?

A method used to identify individuals based on unique patterns in their DNA.

p.22
Methods of Colloid Separation

What is the difference between simple and facilitated diffusion?

Simple diffusion does not require a transport protein, while facilitated diffusion does.

p.16
Biological Functions of Iron

Why are the interactions between GC pairs stronger than between AT pairs?

GC pairs have three hydrogen bonds, while AT pairs have only two, making GC interactions stronger.

p.6
Gibbs Free Energy Equation

What is the oxidation state of carbon-1 in glucose?

Carbon-1 in glucose is oxidized during glycolysis.

p.26
Translation – Protein synthesis

What is the mechanism of translation?

It involves the decoding of mRNA by ribosomes to synthesize proteins.

p.23
Physiological Importance of Amino Acids and Proteins

What is homocellular transport?

Transport of substances between cells of the same type.

p.23
Physiological Importance of Amino Acids and Proteins

What is primary active transport?

The process of moving ions or molecules against their concentration gradient using energy, typically from ATP; an example is the Na+/K+ ATPase.

p.21
Biological Functions of Iron

What are the movements of proteins in the lipid bilayer?

Proteins can move laterally within the bilayer, but their movement can be restricted by various factors.

p.21
Biological Functions of Iron

Which cell membrane has the highest protein content?

The inner mitochondrial membrane.

p.20
Physiological Importance of Amino Acids and Proteins

Among the lipids, what decides membrane fluidity?

The degree of saturation of fatty acids in the phospholipids influences membrane fluidity.

p.3
Physiological Importance of Amino Acids and Proteins

What is indole?

Indole is a heterocyclic compound derived from tryptophan, consisting of a benzene ring fused to a pyrrole ring.

p.6
Isoelectric Point Definition

What are the electric charges of amino acids dependent on?

The pH of the environment.

p.13
Physiological Importance of Amino Acids and Proteins

What is the importance of eicosanoids?

They play crucial roles in inflammation, immunity, and signaling.

p.6
Physiological Importance of Amino Acids and Proteins

What is the biomedical importance of proteins?

Proteins play crucial roles in structure, function, and regulation of the body's tissues and organs.

p.13
Physiological Importance of Amino Acids and Proteins

Name two classes of phospholipids.

Phosphatidylcholine and phosphatidylethanolamine.

p.18
Biological Functions of Iron

What is the coenzyme of vitamins?

Coenzymes derived from vitamins include NAD+ (from niacin) and FAD (from riboflavin).

p.9
Role of EDTA and Desferoxamine

Name at least 2 GAGs and their functions.

Hyaluronic acid (lubrication in joints) and heparin (anticoagulant).

p.11
Physiological Importance of Amino Acids and Proteins

Draw cholesterol ester.

Cholesterol ester is formed by the esterification of cholesterol with a fatty acid.

p.9
Role of EDTA and Desferoxamine

What is a proteoglycan?

A proteoglycan is a protein that is heavily glycosylated, consisting of a core protein and one or more GAG chains.

p.9
Physiological Importance of Amino Acids and Proteins

Which of the following is an optical isomer: Alanine, Galactose, Lactic acid, or All of them?

All of them.

p.10
Physiological Importance of Amino Acids and Proteins

What are the functions of cellulose and starch?

Cellulose provides structural support in plants; starch serves as an energy storage molecule.

p.19
Physiological Importance of Amino Acids and Proteins

What is a proenzyme or zymogen?

An inactive precursor of an enzyme that requires a biochemical change to become active.

p.28
Biological Functions of Iron

What is amino acid activation in protein synthesis?

Amino acid activation is the process where amino acids are attached to their corresponding tRNA molecules.

p.19
Physiological Importance of Amino Acids and Proteins

What is the function of S-adenosylmethionine?

It acts as a methyl donor in various methylation reactions.

p.10
Physiological Importance of Amino Acids and Proteins

What is the structure of maltose?

Maltose consists of two glucose units linked by an alpha-1,4-glycosidic bond.

p.18
Biological Functions of Iron

Describe the structure of NAD+ and its function.

NAD+ consists of a nicotinamide ring, an adenine ring, and two ribose sugars; it functions as an electron carrier in metabolic reactions.

p.30
Methods of Colloid Separation

What is the principle of gene therapy?

To treat or prevent disease by modifying genes.

p.8
Physiological Importance of Amino Acids and Proteins

What is the structure of glucose 6-phosphate?

Glucose 6-phosphate is a phosphorylated form of glucose, with a phosphate group attached to the sixth carbon.

p.2
Physiological Importance of Amino Acids and Proteins

What is the result of a disulfide bond between cysteine residues?

The disulfide bond between cysteine residues forms cystine.

p.15
Biological Functions of Iron

What is PAPS and its function?

PAPS (3'-phosphoadenosine-5'-phosphosulfate) is a sulfate donor in sulfation reactions.

p.24
Biological Functions of Iron

What does DNA ligase catalyze?

Formation of phosphodiester bond in one strand of DNA, synthesis of daughter strand, repair of DNA strand, and removal of DNA primer.

p.15
Biological Functions of Iron

What are the functions of S-adenosylmethionine and folic acid?

SAM is involved in methylation, while folic acid is crucial for DNA synthesis and repair.

p.15
Biological Functions of Iron

What is the function of UTP?

UTP (uridine triphosphate) is involved in the synthesis of RNA and acts as an energy source.

p.20
Physiological Importance of Amino Acids and Proteins

What influences and positions cholesterol in the biological membrane?

Cholesterol influences membrane fluidity and stability by fitting between phospholipid molecules.

p.25
Biological Functions of Iron

Define pseudogenes.

Pseudogenes are non-functional sequences of DNA that resemble functional genes but are not expressed.

p.26
Maturation of mRNA

What region of DNA contains the TATAA box and what is its function?

The promoter region; it is responsible for the binding of RNA polymerase.

p.8
Physiological Importance of Amino Acids and Proteins

What is the biological function of chondroitin sulfate?

Chondroitin sulfate provides structural support in cartilage and helps maintain its elasticity.

p.6
Physiological Importance of Amino Acids and Proteins

What are histones and which amino acids are major components of them?

Histones are proteins that help package DNA, and they are rich in lysine and arginine.

p.14
Physiological Importance of Amino Acids and Proteins

What is the classification and function of fatty acids?

Fatty acids are classified as saturated or unsaturated, and they function as energy sources, components of cell membranes, and signaling molecules.

p.29
Gene manipulation

What type of bond exists between the nitrogenous base and the sugar in DNA and RNA?

Glycosidic bond.

p.5
Physiological Importance of Amino Acids and Proteins

What are essential amino acids?

Essential amino acids are those that cannot be synthesized by the body and must be obtained from the diet.

p.30
Methods of Colloid Separation

What is northern blotting?

A technique used to detect specific RNA sequences in a sample.

p.8
Physiological Importance of Amino Acids and Proteins

What is the difference between starch and cellulose?

Starch is composed of alpha-glucose units and serves as energy storage, while cellulose is made of beta-glucose units and provides structural support in plant cell walls.

p.22
Methods of Colloid Separation

What are ionophores?

Ionophores are compounds that facilitate the transport of ions across lipid membranes.

p.10
Physiological Importance of Amino Acids and Proteins

What type of bond exists between sugar and glycoproteins?

Glycosidic bond.

p.20
Physiological Importance of Amino Acids and Proteins

What is the medical application of lysosomes?

Lysosomes are involved in the degradation of waste materials and can be targeted for therapies in lysosomal storage diseases.

p.20
Physiological Importance of Amino Acids and Proteins

Characterize the asymmetrical lipid bilayer.

The asymmetrical lipid bilayer has different lipid compositions on the inner and outer leaflets, affecting membrane properties and functions.

p.21
Biological Functions of Iron

Which cell membrane has the highest concentration of cholesterol?

The plasma membrane.

p.20
Physiological Importance of Amino Acids and Proteins

What kind of movement do lipids have in the phospholipid bilayer?

Lipids can move laterally within the bilayer, allowing for fluidity and flexibility.

p.15
Biological Functions of Iron

What is deoxyadenosine triphosphate (ATP)?

ATP is the energy currency of the cell, providing energy for various biochemical reactions.

p.24
Biological Functions of Iron

What is telomerase?

An enzyme that adds repetitive nucleotide sequences to the ends of chromosomes (telomeres).

p.19
Physiological Importance of Amino Acids and Proteins

What is tetrahydrobiopterin?

A cofactor involved in the synthesis of neurotransmitters and the metabolism of amino acids.

p.24
Biological Functions of Iron

Describe possibilities of DNA repair modified by alkylating agents.

Alkylating agents can cause mispairing or cross-linking, leading to mutations that can be repaired by various mechanisms including base excision repair.

p.24
Biological Functions of Iron

Name repetitive sequences in DNA.

Telomeres, satellite DNA, and mini-satellites.

p.17
Physiological Importance of Amino Acids and Proteins

What kind of non-covalent interactions can occur between phenylalanine and leucine in a polypeptide chain?

Hydrophobic interactions, hydrogen bonds, and van der Waals forces.

p.18
Biological Functions of Iron

What is the structure and function of pyridoxal phosphate?

Pyridoxal phosphate is the active form of vitamin B6 and acts as a coenzyme in amino acid metabolism.

p.30
Methods of Colloid Separation

What is in situ hybridization?

A technique used to locate specific DNA or RNA sequences in tissues or cells.

p.14
Physiological Importance of Amino Acids and Proteins

What are the components of gangliosides?

Gangliosides are composed of a ceramide and one or more sialic acid-containing oligosaccharides.

p.18
Biological Functions of Iron

What class of enzymes catalyzes the conversion of galactose to glucose?

This reaction is catalyzed by an enzyme belonging to the class of isomerases.

p.6
Physiological Importance of Amino Acids and Proteins

What bonds are involved in the tertiary structure of proteins?

Hydrogen bonds, ionic bonds, disulfide bridges, and hydrophobic interactions.

p.8
Physiological Importance of Amino Acids and Proteins

What is an example of a detoxifying sugar?

An example of a detoxifying sugar is mannose.

p.22
Methods of Colloid Separation

Describe symport, antiport, and uniport.

Symport transports two substances in the same direction, antiport transports two substances in opposite directions, and uniport transports one substance.

p.2
Physiological Importance of Amino Acids and Proteins

Which types of covalent bonds are important for the structure of proteins?

Disulfide bonds, peptide bonds, and ionic bonds are important for protein structure.

p.2
Physiological Importance of Amino Acids and Proteins

What is the heterocyclic ring found in histidine?

The heterocyclic ring in histidine is called imidazole.

p.19
Physiological Importance of Amino Acids and Proteins

Name the coenzymes that act as carriers of one carbon units.

Folic acid and S-adenosylmethionine.

p.25
Biological Functions of Iron

What is a telomere?

A telomere is a repetitive nucleotide sequence at the end of a chromosome that protects it from deterioration.

p.2
Physiological Importance of Amino Acids and Proteins

What is the ring group called in tryptophan?

The ring group in tryptophan is called indole.

p.29
Gene manipulation

What is the principle of gene therapy?

To treat or prevent disease by modifying genes.

p.25
Biological Functions of Iron

What is direct repair of DNA?

Direct repair of DNA involves the correction of damaged DNA without the need for a template.

p.19
Physiological Importance of Amino Acids and Proteins

What kind of reactions do different enzymes catalyze?

Enzymes catalyze reactions such as oxidation-reduction, transfer of functional groups, hydrolysis, and isomerization.

p.24
Biological Functions of Iron

What is base excision DNA repair?

A repair mechanism that removes and replaces damaged or non-canonical bases in DNA.

p.24
Biological Functions of Iron

What is the function of topoisomerase?

To relieve the torsional strain in DNA during replication by cutting and rejoining the DNA strands.

p.20
Physiological Importance of Amino Acids and Proteins

What is covalent modification of enzymes?

A process where enzymes undergo changes in their structure through the addition or removal of chemical groups, affecting their activity.

p.6
Physiological Importance of Amino Acids and Proteins

Draw one hydroxyl amino acid that can be phosphorylated.

Serine.

p.20
Physiological Importance of Amino Acids and Proteins

What kind of covalent modification can regulate enzyme activity?

Phosphorylation and dephosphorylation are common types of covalent modifications that regulate enzyme activity.

p.5
Physiological Importance of Amino Acids and Proteins

Can you name some polypeptides?

Examples include insulin, glucagon, and oxytocin.

p.20
Physiological Importance of Amino Acids and Proteins

What are some medical aspects of enzymes?

Enzymes can be used as biomarkers for diseases, in drug development, and in enzyme replacement therapies.

p.26
Translation – Protein synthesis

What is a frame-shift mutation?

A mutation that alters the reading frame of the genetic code, potentially leading to a completely different protein.

p.29
Gene manipulation

What are the different forms of DNA?

A-DNA, B-DNA, and Z-DNA.

p.10
Physiological Importance of Amino Acids and Proteins

What is the formula and function of fructose?

C6H12O6; fructose serves as a source of energy and is a component of sucrose.

p.18
Biological Functions of Iron

Write the structural formula of one heterocycle that is a component of NAD+ and its function.

The heterocycle is the nicotinamide ring, which is crucial for its role as an electron carrier.

p.29
Gene manipulation

What enzyme is involved in the repair of DNA in eukaryotic cells?

DNA polymerase.

p.10
Physiological Importance of Amino Acids and Proteins

What is the structure and function of starch?

Starch is a polysaccharide made of amylose and amylopectin; it functions as an energy storage molecule in plants.

p.23
Physiological Importance of Amino Acids and Proteins

What is secondary active transport?

Transport of substances across a membrane using the energy from the electrochemical gradient created by primary active transport.

p.23
Physiological Importance of Amino Acids and Proteins

Arrange K+, amino acid, water, and N2 according to membrane permeability.

Water > N2 > Amino acid > K+.

p.19
Physiological Importance of Amino Acids and Proteins

What are the major groups of enzymes?

The major groups include oxidoreductases, transferases, hydrolases, lyases, isomerases, and ligases.

p.25
Biological Functions of Iron

What is transcription?

Transcription is the process of synthesizing RNA from a DNA template.

p.25
Biological Functions of Iron

What is the function of the CAAT sequence?

The CAAT sequence is a promoter element that enhances the transcription of genes.

p.21
Biological Functions of Iron

What is the influence of cholesterol in the biological membrane?

Cholesterol helps to maintain membrane fluidity and stability across varying temperatures.

p.17
Physiological Importance of Amino Acids and Proteins

Explain the chemical structure and biological function of chondroitin sulfate.

Chondroitin sulfate is a glycosaminoglycan composed of repeating disaccharide units; it provides structural support in cartilage and helps maintain its elasticity.

p.31
Physiological Importance of Amino Acids and Proteins

What are the possibilities of DNA repair modified by alkylating agents?

Alkylating agents can cause mutations that may be repaired by base excision repair or nucleotide excision repair mechanisms.

p.2
Physiological Importance of Amino Acids and Proteins

What are glucagon and insulin?

Glucagon is a hormone that raises blood glucose levels, while insulin lowers blood glucose levels.

p.30
Methods of Colloid Separation

What methods are used for DNA amplification?

Polymerase Chain Reaction (PCR) and other amplification techniques.

p.18
Biological Functions of Iron

What is the function of ubiquinone?

Ubiquinone functions in the electron transport chain to shuttle electrons between complexes.

p.28
Biological Functions of Iron

What is the complementary sequence of 3’ AGCTGAC 5’?

5’ TCAGCTG 3’.

p.16
Biological Functions of Iron

What is the formula of guanosine 3-phosphate and its function?

The formula is C10H12N5O10P2; it functions as a signaling molecule in various cellular processes.

p.26
Translation – Protein synthesis

What is the difference between prokaryotic and eukaryotic translation?

Prokaryotic translation occurs simultaneously with transcription, while eukaryotic translation occurs after mRNA processing.

p.23
Physiological Importance of Amino Acids and Proteins

What is a gap junction?

A specialized intercellular connection that allows direct communication between adjacent cells.

p.15
Biological Functions of Iron

What is the structure and function of cAMP?

cAMP (cyclic adenosine monophosphate) acts as a secondary messenger in signal transduction pathways.

p.2
Physiological Importance of Amino Acids and Proteins

How can amino acids bind to glycolipids?

Amino acids can bind to glycolipids through their side chains, forming glycoproteins.

p.23
Physiological Importance of Amino Acids and Proteins

What is facilitated diffusion?

The process of passive transport of molecules across a membrane via specific transmembrane proteins.

p.2
Physiological Importance of Amino Acids and Proteins

What are peptides and their physiological importance?

Peptides are short chains of amino acids that play crucial roles in signaling and metabolic processes.

p.30
Methods of Colloid Separation

What is DNA cloning?

The process of making multiple copies of a specific DNA segment.

p.24
Biological Functions of Iron

What is helicase enzyme?

An enzyme that unwinds the DNA double helix during replication.

p.24
Biological Functions of Iron

What are Okazaki fragments?

Short segments of DNA synthesized on the lagging strand during DNA replication.

p.31
Physiological Importance of Amino Acids and Proteins

Where is glucose transporter GLUT4 localized and what is its function?

GLUT4 is localized in adipose tissue and muscle, facilitating glucose uptake.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of the dipeptide cysteinyl-alanine?

C7H14N2O3S.

p.31
Physiological Importance of Amino Acids and Proteins

What is the principle of gene therapy?

Replacing a faulty gene with a healthy copy or introducing a new gene to help the body fight disease.

p.10
Physiological Importance of Amino Acids and Proteins

Name two glycosaminoglycans (GAGs) and their locations in the body.

Hyaluronic acid (found in connective tissues) and chondroitin sulfate (found in cartilage).

p.21
Biological Functions of Iron

What holds membrane proteins in place?

The lipid bilayer and interactions with other membrane components.

p.28
Biological Functions of Iron

What is the difference between DNA and RNA?

DNA is double-stranded and contains deoxyribose, while RNA is single-stranded and contains ribose.

p.10
Physiological Importance of Amino Acids and Proteins

What is the structure of isomaltose and how is it made?

Isomaltose consists of two glucose units linked by an alpha-1,6-glycosidic bond, formed during the breakdown of starch.

p.19
Physiological Importance of Amino Acids and Proteins

What is the function of NAD+?

It acts as an electron carrier in redox reactions, facilitating the conversion of glucose to energy.

p.19
Physiological Importance of Amino Acids and Proteins

What is NADH and its biological function?

NADH is the reduced form of NAD+ and serves as a key electron donor in cellular respiration.

p.20
Physiological Importance of Amino Acids and Proteins

What is a lipid raft?

Lipid rafts are microdomains in the membrane rich in cholesterol and sphingolipids that organize signaling molecules.

p.15
Biological Functions of Iron

What are the nucleotides UDP and CTP?

UDP (uridine diphosphate) is involved in carbohydrate metabolism, while CTP is involved in RNA synthesis.

p.25
Biological Functions of Iron

Explain the term palindrome in genetics.

A palindrome is a sequence of DNA that reads the same forward and backward, often found in restriction enzyme recognition sites.

p.23
Physiological Importance of Amino Acids and Proteins

What is simple diffusion?

The passive movement of molecules from an area of higher concentration to an area of lower concentration without the need for energy.

p.25
Biological Functions of Iron

Name the post-transcriptional modifications of mRNA.

1. 5' capping 2. Polyadenylation 3. Splicing.

p.31
Physiological Importance of Amino Acids and Proteins

Which lipid is mainly found in the outer layer of the membrane?

Sphingomyelin.

p.31
Physiological Importance of Amino Acids and Proteins

What are the applications of liposomes?

They are used for drug delivery and as models for studying membrane dynamics.

p.17
Physiological Importance of Amino Acids and Proteins

Write the reaction of decarboxylation of glutamic acid.

Glutamic acid (C5H9NO4) loses CO2 to form GABA (C4H9NO2).

p.18
Biological Functions of Iron

Explain the function of S-adenosylmethionine and coenzyme A.

S-adenosylmethionine serves as a methyl donor in methylation reactions, while coenzyme A is involved in the transfer of acyl groups.

p.20
Physiological Importance of Amino Acids and Proteins

What enzyme class do saccharides and fructose belong to?

They belong to the class of enzymes known as glycosidases.

p.19
Physiological Importance of Amino Acids and Proteins

What is a coenzyme?

A non-protein compound that is necessary for the functioning of an enzyme.

p.30
Methods of Colloid Separation

What are DNA libraries?

Collections of cloned DNA fragments that represent the genetic material of an organism.

p.10
Physiological Importance of Amino Acids and Proteins

What is an anomer of mannose and what is an epimer?

An anomer of mannose is alpha-mannose; an epimer is a sugar that differs in configuration at only one specific carbon atom.

p.30
Methods of Colloid Separation

What can DNA fingerprinting not identify?

It cannot determine the exact relationship between individuals.

p.30
Methods of Colloid Separation

What is hydrochirase?

An enzyme involved in the hydrolysis of DNA or RNA.

p.2
Physiological Importance of Amino Acids and Proteins

What is glutathione and what is its function?

Glutathione is a tripeptide that acts as an antioxidant, protecting cells from oxidative stress.

p.24
Biological Functions of Iron

What is DNA polymerase?

An enzyme that synthesizes new DNA strands by adding nucleotides to a growing chain.

p.21
Biological Functions of Iron

What increases membrane fluidity?

Higher temperatures and the presence of unsaturated fatty acids.

p.31
Physiological Importance of Amino Acids and Proteins

What class of enzyme catalyzes the conversion of fructose-1,6-bisphosphate?

Lyases.

p.31
Physiological Importance of Amino Acids and Proteins

What is the complementary sequence of the DNA strand 3’ GATCGA 5’?

5’ CTAGCT 3’.

p.31
Physiological Importance of Amino Acids and Proteins

What are isoenzymes?

Enzymes with the same catalytic activity but different chemical structures.

p.29
Gene manipulation

What is the role of peptidyl-transferase in translation?

It catalyzes the formation of peptide bonds between amino acids.

p.5
Physiological Importance of Amino Acids and Proteins

From which amino acids is choline formed?

Choline is formed from serine and methionine.

p.21
Biological Functions of Iron

What are peripheral proteins?

Proteins that are loosely attached to the membrane surface and can be easily removed.

p.25
Biological Functions of Iron

What can affect DNA and what diseases can result from mutagens?

Mutagens can cause mutations leading to diseases such as cancer, genetic disorders, and developmental issues.

p.30
Methods of Colloid Separation

What is southern blotting?

A method used to detect specific DNA sequences in a sample.

p.2
Physiological Importance of Amino Acids and Proteins

What is the formula of the heterocycle that is a constituent of tryptophan?

The heterocycle is indole, with the formula C8H7N.

p.15
Biological Functions of Iron

What is PAPS?

PAPS stands for 3'-phosphoadenosine-5'-phosphosulfate, a key molecule in sulfate metabolism.

p.23
Physiological Importance of Amino Acids and Proteins

What is the structure of a nucleosome?

A nucleosome consists of a segment of DNA wrapped around a core of histone proteins.

p.23
Physiological Importance of Amino Acids and Proteins

What is the main DNA repair mechanism?

Nucleotide excision repair.

p.24
Biological Functions of Iron

What does it mean that DNA replication is semiconservative and semi-continuous?

Semiconservative means each new DNA molecule contains one original and one new strand; semi-continuous means the leading strand is synthesized continuously while the lagging strand is synthesized in fragments.

p.31
Physiological Importance of Amino Acids and Proteins

What characterizes asymmetrical lipid distribution in the plasma membrane?

Different types of lipids are distributed unevenly between the inner and outer layers.

p.17
Physiological Importance of Amino Acids and Proteins

Describe the tertiary structure of proteins.

The tertiary structure is the three-dimensional shape formed by the folding of a polypeptide chain, stabilized by interactions such as hydrogen bonds, ionic bonds, hydrophobic interactions, and disulfide bridges.

p.17
Physiological Importance of Amino Acids and Proteins

What types of bonds are important for the structure of proteins?

Hydrogen bonds, ionic bonds, disulfide bridges, and hydrophobic interactions.

p.31
Physiological Importance of Amino Acids and Proteins

What is the structure and function of telomeres?

Telomeres are repetitive nucleotide sequences at the ends of chromosomes that protect them from degradation.

p.17
Physiological Importance of Amino Acids and Proteins

Describe the bond between ribose and nitrogenous bases in nucleotides.

The bond is a glycosidic bond formed between the 1' carbon of ribose and the nitrogen atom of the nitrogenous base.

p.28
Biological Functions of Iron

What is the regulation level of translation?

Translation can be regulated by factors such as initiation factors, ribosome availability, and mRNA stability.

p.2
Physiological Importance of Amino Acids and Proteins

What is the product of the decarboxylation of histidine and the enzyme involved?

The product is histamine, and the enzyme is histidine decarboxylase.

p.19
Physiological Importance of Amino Acids and Proteins

What is NADP and its function?

NADP is a coenzyme that plays a crucial role in anabolic reactions, including fatty acid and nucleic acid synthesis.

p.19
Physiological Importance of Amino Acids and Proteins

What factors influence enzyme activity?

Factors include temperature, pH, substrate concentration, and the presence of inhibitors or activators.

p.30
Methods of Colloid Separation

What is western blotting?

A technique used to detect specific proteins in a sample.

p.21
Biological Functions of Iron

What are integral proteins?

Proteins that are embedded within the lipid bilayer and span across the membrane.

p.23
Physiological Importance of Amino Acids and Proteins

What is translation?

The process of synthesizing proteins from mRNA templates.

p.17
Physiological Importance of Amino Acids and Proteins

What is the name and formula of the heterocycle component of histidine?

Imidazole; C3H4N2.

p.31
Physiological Importance of Amino Acids and Proteins

What is transcellular transport?

It is the movement of substances across a cell layer, such as glucose transport through intestinal cells.

p.17
Physiological Importance of Amino Acids and Proteins

Write the decarboxylation reaction of glutamic acid and describe the importance of the product.

Glutamic acid (C5H9NO4) decarboxylates to form gamma-aminobutyric acid (GABA); GABA is an important neurotransmitter in the central nervous system.

p.31
Physiological Importance of Amino Acids and Proteins

What is substrate specificity of enzymes?

The ability of an enzyme to selectively catalyze a specific reaction with a particular substrate.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of 5-fluorouracil and describe its medical importance?

C4H3FN2O2; it is used as a chemotherapy agent to inhibit cancer cell growth.

p.24
Biological Functions of Iron

What is the difference between leading strand and lagging strand?

The leading strand is synthesized continuously, while the lagging strand is synthesized in short segments called Okazaki fragments.

p.24
Biological Functions of Iron

Name three chemical mutagens.

Alkylating agents, base analogs, and intercalating agents.

p.24
Biological Functions of Iron

Describe prokaryotic and eukaryotic replication.

Prokaryotic replication is typically circular and occurs in the cytoplasm, while eukaryotic replication is linear and occurs in the nucleus.

p.24
Biological Functions of Iron

What is direct repair?

A mechanism that directly reverses DNA damage without removing the damaged base.

p.30
Methods of Colloid Separation

What happens during PCR at 72°C?

DNA polymerase synthesizes new DNA strands.

p.23
Physiological Importance of Amino Acids and Proteins

What is the difference between eukaryotic and prokaryotic replication?

Eukaryotic replication occurs in multiple origins and is more complex, while prokaryotic replication typically starts at a single origin and is simpler.

p.21
Biological Functions of Iron

Characterize asymmetrical lipid distribution in plasma membrane.

Certain lipids are preferentially located in the outer leaflet, while others are found in the inner leaflet.

p.31
Physiological Importance of Amino Acids and Proteins

What is the secondary structure of DNA?

The secondary structure of DNA is a double helix.

p.31
Physiological Importance of Amino Acids and Proteins

Why is DNA replication described as semiconservative?

Because each new DNA molecule consists of one original strand and one newly synthesized strand.

p.31
Physiological Importance of Amino Acids and Proteins

Where is aminoacyl-tRNA bound during protein synthesis?

To the 3’ end of tRNA.

p.17
Physiological Importance of Amino Acids and Proteins

Draw the reaction of glucose oxidation on carbon atom C-1 and name the product.

The product is gluconic acid; the reaction involves the oxidation of the aldehyde group at C-1.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of valine?

C5H11NO2.

p.31
Physiological Importance of Amino Acids and Proteins

What effect does the saturation of fatty acids have on membrane fluidity?

It decreases membrane fluidity.

p.31
Physiological Importance of Amino Acids and Proteins

What are the main forms of DNA?

A-DNA, B-DNA, and Z-DNA.

p.31
Physiological Importance of Amino Acids and Proteins

What is a key difference in transcription between eukaryotic and prokaryotic DNA?

Eukaryotic transcription occurs in the nucleus and involves RNA processing, while prokaryotic transcription occurs in the cytoplasm without processing.

p.31
Physiological Importance of Amino Acids and Proteins

What are the mutagenic properties of nitrous acid?

Nitrous acid can deaminate bases, leading to mispairing during DNA replication.

p.17
Physiological Importance of Amino Acids and Proteins

Give a definition of peptides and explain their physiological importance.

Peptides are short chains of amino acids linked by peptide bonds; they play crucial roles in signaling, hormone regulation, and as building blocks for proteins.

p.25
Biological Functions of Iron

Explain transcription.

Transcription involves the enzyme RNA polymerase binding to DNA and synthesizing RNA by complementary base pairing.

p.31
Biological Functions of Iron

What is the function of NAD+?

It acts as an electron carrier in metabolic reactions.

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Physiological Importance of Amino Acids and Proteins

What is the formula of a cyclic amino acid?

Proline; C5H9NO2.

p.17
Physiological Importance of Amino Acids and Proteins

Name w-3 unsaturated fatty acids and write the formula of one of them.

Alpha-linolenic acid; C18H30O2.

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Physiological Importance of Amino Acids and Proteins

What is the formula of mannose?

C6H12O6.

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Physiological Importance of Amino Acids and Proteins

What is the formula of palmitic acid?

C16H32O2.

p.24
Biological Functions of Iron

What is the structure of telomerase?

Telomerase consists of a protein component and an RNA template that guides the addition of telomeric repeats.

p.31
Biological Functions of Iron

What vitamins are related to NADPH and pyridoxine?

NADPH - Niacin and pyridoxine - Vitamin B6.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of lactose, and what are its components?

C12H22O11; composed of glucose and galactose.

p.17
Physiological Importance of Amino Acids and Proteins

Describe the structure and function of starch.

Starch is a polysaccharide composed of amylose and amylopectin; it serves as a primary energy storage molecule in plants.

p.31
Physiological Importance of Amino Acids and Proteins

What does DNA ligase catalyze?

The formation of phosphodiester bonds to join DNA fragments.

p.31
Biological Functions of Iron

Name at least two coenzymes that participate in oxidation-reduction reactions.

NAD+ and FAD.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of phosphatidylserine?

C18H37N2O8P.

p.17
Physiological Importance of Amino Acids and Proteins

Describe the structure and function of glucagon.

Glucagon is a peptide hormone composed of 29 amino acids; it raises blood glucose levels by promoting glycogen breakdown in the liver.

p.17
Physiological Importance of Amino Acids and Proteins

Draw the formula of CTP and explain its biological function.

CTP (cytidine triphosphate) has the formula C9H14N3O14P3; it is involved in lipid synthesis and acts as an energy source.

p.31
Physiological Importance of Amino Acids and Proteins

What is a stop codon?

A nucleotide triplet that signals the termination of protein synthesis.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of the heterocycle that is a constituent of tryptophan?

Indole; C8H7N.

p.17
Physiological Importance of Amino Acids and Proteins

What is the formula of lactose and explain its function?

C12H22O11; lactose is a sugar that provides energy and is important for the nutrition of infants.

Study Smarter, Not Harder
Study Smarter, Not Harder