What are the three basic layers of the skin?
Epidermis, Dermis, and Hypodermis.
What happens when the top layer of the skin does not exfoliate well?
The cells can fall back and cause a blockage, leading to the accumulation of sebum.
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p.4
Layers of Skin

What are the three basic layers of the skin?

Epidermis, Dermis, and Hypodermis.

p.19
Acne Formation and Treatment

What happens when the top layer of the skin does not exfoliate well?

The cells can fall back and cause a blockage, leading to the accumulation of sebum.

p.11
Dermis and Hypodermis Functions

What happens when elastin fibers in the dermis are damaged?

The skin loses its stretchability and increases in strength.

p.6
Dermis and Hypodermis Functions

What type of cells are found in the hypodermis?

Superficial fat cells, also known as white fat cells.

p.26
Sunburn and UV Protection

What was the concentration of 1,25D used in the study?

0.1 µg/cm².

p.15
Nerve Endings and Sensation in Skin

What is a dermatome?

An area of skin that is mainly supplied by a single spinal nerve.

p.11
Dermis and Hypodermis Functions

What are the main fibers found in the dermis?

Collagen and elastin fibers.

p.21
Sunburn and UV Protection

What role does ozone play in protecting against sunburn?

Ozone disrupts the transmission of ultraviolet radiation with wavelengths less than 290 nm.

p.9
Layers of Skin

What type of glands are present in 'thick' skin?

Sweat glands.

p.26
Sunburn and UV Protection

What was the purpose of the study by Damian et al. in Exp Derm. 2010?

To identify 'photoprotective' agents for sunscreens and after sun lotions.

p.14
Nerve Endings and Sensation in Skin

Where are Meissner’s corpuscles located?

At the top of the dermis.

p.5
Functions of Skin

What is the largest organ of the body?

The skin.

p.13
Skin Appendages

What is the primary function of eccrine sweat glands?

Temperature regulation.

p.10
Major Skin Cell Types

What is the primary function of keratinocytes?

They act as a barrier and provide external covering.

p.20
Acne Formation and Treatment

Does a Vitamin A derivative kill off bacteria directly in acne treatment?

No, it creates an unfavourable environment for bacteria instead.

p.17
Common Skin Conditions

What percentage of Australian adolescents aged 16-18 years are affected by acne?

More than 90%.

p.6
Layers of Skin

What are the three main layers of the skin?

Epidermis, Dermis, and Hypodermis.

p.25
Nerve Endings and Sensation in Skin

What does Botulinum toxin block?

Nerve signals that cause muscles to contract and sweat gland activation.

p.19
Acne Formation and Treatment

What accumulates when the top layer of the skin does not exfoliate properly?

Shed cells and sebum from sebaceous glands.

p.7
Layers of Skin

What is the most superficial layer of the skin?

The epidermis.

p.20
Acne Formation and Treatment

What indirect effect does a Vitamin A derivative have on bacterial growth?

It reduces bacterial growth indirectly.

p.20
Acne Formation and Treatment

How does a Vitamin A derivative affect follicle keratinisation?

It normalises follicle keratinisation.

p.23
Skin Structure and Composition

How many categories are there in the Fitzpatrick skin type classification?

There are six categories.

p.12
Dermis and Hypodermis Functions

What is one of the primary functions of the hypodermis?

Anchors the skin to underlying structures.

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type III?

Medium skin, sometimes burns, gradually tans.

p.9
Layers of Skin

Where on the body is the epidermis much thicker?

On the soles of the feet and palms of the hands.

p.16
Skin Appendages

What do sebaceous glands produce and secrete?

Sebum.

p.2
Functions of Skin

What are some of the major functions of the skin?

The major functions of the skin include protection, regulation of body temperature, sensation, and synthesis of vitamin D.

p.9
Layers of Skin

How does increased friction affect the thickness of the skin?

Increased friction leads to increased thickness of the skin.

p.14
Nerve Endings and Sensation in Skin

Where on the body are Pacinian corpuscles commonly found?

Fingertips.

p.7
Functions of Skin

What is the primary function of the epidermis?

Protection.

p.23
Skin Structure and Composition

What is the Fitzpatrick skin type classification used for?

It is used to classify human skin color and its response to UV radiation.

p.10
Major Skin Cell Types

What percentage of the epidermis is made up of melanocytes?

5%

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type II?

Fair skin, usually burns, tans minimally.

p.19
Major Skin Cell Types

What is the normal function of keratinocytes in the epidermis?

Keratinocytes in the epidermis should exfoliate.

p.6
Major Skin Cell Types

What is the primary characteristic of cells in the epidermis?

They are full of keratin.

p.24
Dermis and Hypodermis Functions

Where is the blood supply located in the skin?

In the dermis.

p.7
Major Skin Cell Types

What is the main cell type in the epidermis?

Keratinocytes.

p.12
Dermis and Hypodermis Functions

What is the hypodermis also known as?

Subcutaneous fat or superficial fascia.

p.13
Skin Appendages

Where do sebaceous glands secrete sebum?

Into the hair follicle.

p.22
Sunburn and UV Protection

What role does melanin play in protecting the skin from UV radiation?

Melanin absorbs and scatters UV radiation, acting as a free radical quencher.

p.13
Skin Appendages

What are nails composed of?

Plates of keratinized cells.

p.22
Major Skin Cell Types

Where are melanocytes located in the skin?

Melanocytes sit in the basal part, the bottom level of the epidermis.

p.12
Dermis and Hypodermis Functions

How does the thickness of the hypodermis vary?

It has variable thickness depending on the location and individual.

p.22
Major Skin Cell Types

How is melanin transferred to keratinocytes?

Melanin is produced by melanocytes and transferred into neighboring keratinocytes via melanosomes.

p.17
Common Skin Conditions

What impact does acne have on individuals?

It has a profound impact on self-esteem, mood, and psychological status.

p.11
Dermis and Hypodermis Functions

What unique pattern is found between the epidermis and dermis?

Fingerprints, which are genetically unique patterns seen microscopically as undulations.

p.16
Skin Appendages

What happens to sebaceous gland cells after they produce sebum?

The cells die.

p.24
Dermis and Hypodermis Functions

Why is inflammation necessary in the dermis?

Because the dermis has a lot of fibrous tissues.

p.5
Functions of Skin

What percentage of total body mass does the skin constitute?

15 - 20%.

p.5
Functions of Skin

What are the primary functions of the skin?

Physical barrier, thermoregulation, sense organ, immunological, Vitamin D production, and excretion.

p.10
Major Skin Cell Types

What is the primary function of melanocytes?

They produce pigment.

p.1
Functions of Skin

What is the primary function of the epidermis?

To act as a barrier to protect the body from the external environment.

p.22
Sunburn and UV Protection

What determines sunburn sensitivity?

Sunburn sensitivity is determined by melanin and skin thickness.

p.4
Skin Appendages

What are the accessory structures of the skin?

Hair, Hair follicles, Sweat glands, Sebaceous glands, and Nails.

p.21
Sunburn and UV Protection

What causes sunburn?

Ultraviolet radiation.

p.9
Layers of Skin

What type of glands are absent in 'thick' skin?

Sebaceous glands.

p.2
Functions of Skin

How can the skin barrier be compromised?

The skin barrier can be compromised by factors such as physical damage, chemical exposure, excessive washing, and certain skin conditions.

p.16
Skin Appendages

What type of secretion involves the 'suicide' of the cell to release its contents?

Holocrine secretion.

p.13
Skin Appendages

Where does the apocrine sweat gland empty its secretion?

Into the hair follicle.

p.26
Sunburn and UV Protection

What institution conducted the skin research mentioned in the text?

The University of Sydney (Usyd).

p.12
Dermis and Hypodermis Functions

What types of tissues are found in the hypodermis?

Loose connective tissue and adipose tissue.

p.5
Functions of Skin

How does the skin contribute to thermoregulation?

Through mechanisms such as sweating and blood vessel dilation or constriction.

p.18
Acne Formation and Treatment

What is the first step in the formation of acne?

Accumulation of shed dead cells and keratin.

p.18
Acne Formation and Treatment

What happens after the accumulation of dead cells and keratin in acne formation?

Excess sebum production.

p.10
Common Skin Conditions

What type of cell mutation is associated with melanoma?

Melanocyte cell mutation.

p.11
Dermis and Hypodermis Functions

What is the primary function of the dermis?

The dermis provides tensile strength and stretch.

p.4
Layers of Skin

Which layer of the skin does not have a blood supply?

The Epidermis.

p.16
Skin Appendages

What is the function of sebum?

Sebum coats hair and skin surface.

p.14
Nerve Endings and Sensation in Skin

Where are Pacinian corpuscles located?

In the deeper dermis and hypodermis.

p.16
Skin Appendages

Where is sebum discharged?

Into the hair follicle.

p.26
Sunburn and UV Protection

What does CPD positive nuclei as % total nuclei measure?

It measures the extent of DNA damage in cells exposed to UV radiation.

p.20
Acne Formation and Treatment

How does a Vitamin A derivative affect sebum production?

It reduces sebum production.

p.13
Skin Appendages

What is the characteristic of the sweat produced by apocrine sweat glands?

It is smelly.

p.10
Major Skin Cell Types

What percentage of the epidermis is made up of keratinocytes?

85%

p.13
Nerve Endings and Sensation in Skin

What is the role of nerve endings in the skin?

For sensation.

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type IV?

Olive skin, rarely burns, tans easily.

p.2
Layers of Skin

What are the main layers of the skin?

The main layers of the skin are the epidermis, dermis, and hypodermis.

p.2
Major Skin Cell Types

What are the major constituents of the skin?

The major constituents of the skin include keratinocytes, melanocytes, Langerhans cells, and Merkel cells.

p.6
Layers of Skin

What happens to the cells in the epidermis over time?

They peel off.

p.6
Dermis and Hypodermis Functions

What is the function of the dermal papillae?

They increase the surface area for exchange of oxygen, nutrients, and waste products between the dermis and epidermis.

p.20
Acne Formation and Treatment

What is a key characteristic of a Vitamin A derivative in acne treatment?

It causes shrinkage of sebaceous glands.

p.14
Nerve Endings and Sensation in Skin

What sensations do Meissner’s corpuscles detect?

Light touch.

p.14
Nerve Endings and Sensation in Skin

Where on the body are Meissner’s corpuscles commonly found?

Lips and palms.

p.20
Acne Formation and Treatment

What anti-inflammatory effect does a Vitamin A derivative have in acne treatment?

It has anti-inflammatory properties.

p.7
Skin Structure and Composition

What happens to keratinocytes as they move up the layers of the epidermis?

They differentiate and are eventually exfoliated from the top layer.

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type I?

Very fair skin, always burns, never tans.

p.5
Functions of Skin

How does the skin function as an excretory organ?

Through the secretion of sweat and other substances.

p.18
Acne Formation and Treatment

Which bacteria is involved in the proliferation during acne formation?

Cutibacterium acnes.

p.17
Acne Formation and Treatment

What potential consequence does moderate-to-severe acne have?

It has the potential to cause permanent scarring.

p.9
Layers of Skin

What is a characteristic of 'thick' skin?

'Thick' skin has no hair follicles.

p.25
Nerve Endings and Sensation in Skin

How does Botulinum toxin help in reducing wrinkles?

By blocking nerve signals that cause muscles to contract, thus relaxing wrinkles.

p.25
Nerve Endings and Sensation in Skin

How does Botulinum toxin treat hyperhidrosis?

By blocking nerve signals that activate sweat glands.

p.14
Nerve Endings and Sensation in Skin

What sensations do Pacinian corpuscles detect?

Pressure changes and vibrations.

p.26
Sunburn and UV Protection

What was the effect of UV exposure on vehicle-treated cells in the study?

The study measured CPD positive nuclei as a percentage of total nuclei to assess DNA damage.

p.7
Major Skin Cell Types

What percentage of the epidermis is made up of keratinocytes?

Approximately 85%.

p.13
Skin Appendages

What triggers the contraction of the arrector pili muscle?

It causes sebaceous gland secretion into the hair follicle and results in goosebumps.

p.1
Layers of Skin

What are the three main layers of the skin?

Epidermis, dermis, and hypodermis.

p.1
Functions of Skin

What are the main functions of the skin?

Protection, regulation, and sensation.

p.7
Layers of Skin

From which layer do keratinocytes originate?

The basal layer (stratum basale) of the epidermis.

p.5
Functions of Skin

What role does the skin play in the immune system?

It acts as an immunological barrier, protecting against pathogens.

p.7
Skin Structure and Composition

What process do keratinocytes undergo as they migrate upwards through the epidermis?

Keratinization.

p.5
Functions of Skin

How is Vitamin D produced in the skin?

It is produced in skin cells when exposed to sunlight.

p.5
Functions of Skin

What are other sources of Vitamin D besides sunlight?

Oily fish and supplements.

p.10
Major Skin Cell Types

What percentage of the epidermis is made up of Merkel’s cells?

6-10%

p.3
Major Skin Cell Types

What are the major cell types found in the skin?

Keratinocytes, melanocytes, Langerhans cells, and Merkel cells.

p.12
Dermis and Hypodermis Functions

What are two key roles of the hypodermis?

Energy storage and insulation.

p.10
Major Skin Cell Types

What percentage of the epidermis is made up of Langerhans’ cells?

2-5%

p.7
Major Skin Cell Types

What happens to keratinocytes as they become full of keratin?

They lose their nucleus and become non-epithelial cells.

p.10
Major Skin Cell Types

What is the primary function of Langerhans’ cells?

They are immune cells.

p.22
Functions of Skin

What gives skin its color?

The transfer of melanin into keratinocytes gives skin its color.

p.18
Acne Formation and Treatment

What can severe inflammation in acne lead to?

Scarring.

p.18
Acne Formation and Treatment

What accumulates along with keratin in the formation of acne?

Sebum.

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type V?

Brown skin, very rarely burns, tans very easily.

p.10
Major Skin Cell Types

What is the primary function of Merkel’s cells?

They are involved in sensation.

p.22
Major Skin Cell Types

What is the function of melanocytes?

Melanocytes produce melanin, a pigment that protects the skin from UV radiation.

p.1
Skin Appendages

What are the skin appendages?

Hair, nails, sweat glands, and sebaceous glands.

p.3
Layers of Skin

What are the three main layers of the skin?

The epidermis, dermis, and hypodermis.

p.23
Skin Structure and Composition

What characterizes Fitzpatrick Skin Type VI?

Dark brown or black skin, never burns, deeply pigmented.

p.1
Acne Formation and Treatment

What causes acne formation?

Blocked hair follicles and oil glands, often due to excess oil production, bacteria, and dead skin cells.

p.18
Acne Formation and Treatment

Which gland is primarily involved in the production of sebum in acne formation?

Sebaceous gland.

p.3
Common Skin Conditions

What are some common conditions affecting the structure of the skin?

Conditions such as eczema, psoriasis, and dermatitis.

p.3
Sunburn and UV Protection

What causes sunburn and how can it be prevented?

Sunburn is caused by overexposure to ultraviolet (UV) radiation from the sun, and it can be prevented by using sunscreen, wearing protective clothing, and avoiding peak sun hours.

p.1
Dermis and Hypodermis Functions

Which layer of the skin contains blood vessels, nerves, and hair follicles?

The dermis.

p.1
Major Skin Cell Types

What type of cells are primarily found in the epidermis?

Keratinocytes.

p.1
Major Skin Cell Types

What is the role of melanocytes in the skin?

To produce melanin, which gives skin its color and protects against UV radiation.

p.22
Sunburn and UV Protection

What type of damage can UVA radiation cause to the skin?

UVA radiation can cause oxidative damage, DNA damage, skin aging issues, and wrinkles.

p.18
Acne Formation and Treatment

What type of inflammation is associated with severe acne?

Marked inflammation.

p.3
Skin Appendages

What are skin appendages?

Structures such as hair, nails, sweat glands, and sebaceous glands that originate from the skin.

p.3
Acne Formation and Treatment

What is acne and how does it form?

Acne is a skin condition that occurs when hair follicles become clogged with oil and dead skin cells, leading to inflammation and pimples.

p.18
Acne Formation and Treatment

What follows bacterial proliferation in the acne formation process?

Inflammation.

p.1
Dermis and Hypodermis Functions

What is the function of the hypodermis?

To provide insulation and cushioning for the body.

p.18
Acne Formation and Treatment

What type of inflammation is associated with mild acne?

Mild inflammation.

p.22
Sunburn and UV Protection

How does melanin protect DNA from UV radiation?

Melanin absorbs UV radiation, preventing it from being absorbed by DNA and causing damage.

p.1
Sunburn and UV Protection

How does the skin protect against UV radiation?

By producing melanin, which absorbs and dissipates UV rays.

p.3
Common Skin Conditions

What are burns and how are they classified?

Burns are injuries to the skin caused by heat, chemicals, electricity, or radiation. They are classified into first-degree, second-degree, and third-degree burns based on their severity.

p.3
Functions of Skin

What are the overall structure and function of the skin?

The skin is the body's largest organ, providing a protective barrier against environmental hazards, regulating temperature, and enabling sensory perception.

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