p.2
Composition of Platelets: Hyalomere and Granulomere
What are the two main parts of platelets?
Outer pale part (Hyalomere) and inner granular part (Granulomere).
p.5
Development and Precursor Cells of Platelets
What type of stem cell gives rise to blood platelets?
Hematopoietic stem cell (HSC).
p.9
Mechanism of Platelet Release from Megakaryocytes
What happens to proplatelets in the sinusoid?
They fragment, releasing platelets inside the blood sinusoid.
p.1
Function of Platelets in Blood Clotting
What is the primary function of platelets?
To promote blood clotting and help repair minor injuries in blood vessels.
p.3
Peripheral Marginal Bundle and Cytoskeleton of Platelets
What is the function of the peripheral marginal bundle in platelets?
To maintain the shape of the platelet using microtubules and microfilaments.
p.4
Composition of Platelets: Hyalomere and Granulomere
What do delta (δ) granules contain?
Serotonin, ATP, ADP, calcium, and magnesium ions.
p.3
Composition of Platelets: Hyalomere and Granulomere
What are the two main components of platelets mentioned?
Hyalomere (H) and Granulomere (G).
p.6
Development and Precursor Cells of Platelets
How do megakaryoblasts divide under the influence of thrombopoietin?
By endomitosis (nuclear replication without cell division).
p.4
Composition of Platelets: Hyalomere and Granulomere
What are glycogen granules?
Storage form of glucose in cells.
p.6
Megakaryocyte Characteristics and Function
What are the results of megakaryoblast division?
Large size and polyploid cells.
p.4
Composition of Platelets: Hyalomere and Granulomere
What are alpha (α) granules known to contain?
Fibrinogen, platelet-derived growth factor (PDGF), and proteins related to adhesion and blood clotting.
p.9
Mechanism of Platelet Release from Megakaryocytes
What are proplatelets?
Pseudopodia extruded by mature megakaryocytes into the sinusoid lumens.
p.7
Megakaryocyte Characteristics and Function
Where are megakaryocytes primarily located?
Scattered in the bone marrow, more adjacent to the blood sinusoids.
p.1
Structure and Shape of Blood Platelets
Do blood platelets have a nucleus?
No, they do not have a nucleus.
p.3
Open Canalicular System in Platelets
What is the open canalicular system in platelets connected to?
The cell membrane for transport of factors with the blood plasma.
p.1
Function of Platelets in Blood Clotting
How do platelets help prevent blood loss?
By repairing tears in the walls of small blood vessels.
p.4
Composition of Platelets: Hyalomere and Granulomere
What organelles are mentioned alongside glycogen granules?
Lysosomes and mitochondria.
p.7
Megakaryocyte Characteristics and Function
Describe the nucleus of a megakaryocyte.
Large, irregular, lobulated, and polyploid.
p.9
Megakaryocyte Characteristics and Function
What characterizes a mature megakaryocyte?
A large cytoplasm filled with granules.
p.9
Megakaryocyte Characteristics and Function
What are demarcation membranes?
Extensive invaginations of the plasma membrane that form the basis for fragmentation of the megakaryocyte into individual blood platelets.
p.3
Role of Glycocalyx in Platelet Activation
What role does the glycocalyx play in blood platelets?
It is involved in platelet adhesion and activation during the coagulation process.
