Alka-Seltzer.
Sucrose and lactose.
They assist the breakup and distribution of a tablet or capsule content in the stomach.
Inserted into the vagina for local effects.
Gelcaps.
Dissolution into a small particle solution.
Within minutes.
To enhance flow properties of powders.
Aspirin enteric-coated tablets.
The tablet has a dull and rough appearance on the surface.
Tablets that can be layered or compression-coated.
Two single doses: one for immediate release and one for delayed release.
Rapidly when used sublingually or buccally.
To enhance drug dissolution.
Sublingual, buccal, and vaginal.
To provide cohesion to the powder, aiding in the transfer of the powder blend into tablets or capsule shells.
They help in the absorption of moisture and other substances.
Sugar-acacia base.
Unequal color distribution.
Partial or complete separation of the top or bottom crown from the main body of the tablet.
By compression.
Fentanyl Actiq.
They are specifically designed for administration in the vaginal area.
To improve the taste of the tablet.
Fumed silicon dioxide.
In a dry, cool place.
Uncoated aspirin, acetaminophen, ibuprofen.
Suitable pharmaceutical excipients.
By compressing a tablet granulation around a previously compressed granulation.
CMC.
They help hold the ingredients together in a tablet.
Tablet triturates.
Release the drug in the intestinal media.
Less than 1%.
Friabilator.
Dissolution tester.
Very soluble in water.
By compression or molding.
Sodium lauryl sulfate.
Compact the shell (outer tablet).
A type of lozenge that can have various bases.
Polyethylene glycol (PEG) base.
Careful handling of the syrup and monitoring of temperatures.
Ibuprofen and lamivudine.
Capping, lamination, picking, sticking, and mottling.
Powders, granules, alone or with excipients.
Tablet triturates.
A dark-colored, airtight, glass container.
Insoluble in gastric media but soluble in intestinal media.
It is used as a disintegrant in tablets and capsules.
Separation of a tablet into two or more distinct layers.
Chocolate.
Sugar.
They are more tamper evident than unsealed capsules.
To test the durability of tablets during transit.
Adhesion of the tablet material to the die wall, leading to a loss of the polished face on the punch.
To prevent destruction of the drug by gastric juices and irritation of the stomach by the drug.
In a dry, cool place.
To prevent volatility and mitigate within the bottle.
They contain a mild effervescent drug complex.
Metformin 500 mg as the outer coat and Pioglitazone 15 mg as the core tablet.
To aid in the formation of the tablet.
Either buccally or sublingually.
Gum base.
To increase the bulk of the tablet.
They reduce friction during tablet compression.
Tablets that consist of a tablet within a tablet.
Uncoated bullet-shaped or ovoid tablets.
Many pain relief and fever reducer products.
They can be one-third smaller than a capsule with an equivalent amount of powder.
149 – 154 °C (300 – 310 °F).
They provide sweetness to mask unpleasant tastes.
They increase formulation efficiency and resistance to chipping.
Topical or systemic effects.
To promote absorption of the drug in the intestine.
By repeated compression to create multiple layers.
Wash the affected area immediately with soap and water.
They are helpful for children or people who cannot swallow whole tablets.
Using sugar candy and lozenge molds.
Alcohol and water.
Hard rubber or metal.
To release the drug in the intestinal area, often taken on an empty stomach.
Tablets designed to be chewed before swallowing.
Progesterone and prochlorperazine.
They provide rapid drug effects.
Tablets absorbed through the oral mucosa; example: progesterone.
They are the most commonly used solid dosage forms, primarily for oral administration.
Multivitamins and antibacterials.
Disintegration of the solid.
Sucrose and other sugars and/or carbohydrates.
Smaller particles dissolve more easily, facilitating absorption.
Film former (polymers), alloying substance (usually PEG), plasticizer, surfactant, and others.
Due to the efficiency of the film-coating process.
Calcium stearate, stearic acid, and talc.
By punches and dies.
To separate physically or chemically incompatible ingredients and/or to produce repeat action/prolonged action tablets.
To provide a barrier to objectionable taste and odor.
Heat or moisture.
They are usually more expensive.
They produce a carbonated solution and effervescence.
Slowly in the mouth.
Tablets intended to be swallowed intact, excluding chewable tablets.
Tablets that provide both immediate and delayed release, such as Repetabs.
Magnesium stearate.
For aesthetic appeal and identification.
Capsules.
It can hinder drug dissolution, making wetting agents necessary.
Compact the core (inner tablet).
Lactose.
They are dissolved in water before administration to prepare solutions.
They facilitate swallowing.
Compressed tablets coated with a thin layer of film-coating.
Localized portions of the tablet face are missing.
The extent and rate of solution formation from a dosage form.
Disintegration tester.
Tablets that can be split.
Many vitamins, antacids, and antibiotics.
They are more complicated to produce than simple compressed tablets.
Dissolved in water prior to administration.
No, they usually contain no disintegrants.
For sublingual or chewable tablets.
Topical or systemic effects.
They assist in the breakup and distribution of the tablet/capsule content in the stomach.
To enhance the solubility of the active ingredients.
Nitroglycerin.
Tablets that provide a sustained release of medication over time.
Starch and Croscarmellose.
Microcrystalline cellulose.
Starch.
To enhance the appearance and aid in identification.
Removal of the surface material of a tablet by a punch, resulting in localized portions of the tablet face being missing.
How quickly the tablet breaks down into smaller particles.
Products containing volatile ingredients or those that can penetrate through the skin.
Hard and soft lozenges.
Approximately 65 mg.
Admixture of Phenylephedrine HCl and Ascorbic Acid with Paracetamol.
Using a tablet machine with large and flat punches.
To treat cough and cold symptoms with minor sore throat.
A method used for molding lozenges.
Coated tablets (sugar, chocolate, film, gelatin, enteric), delayed action, repeat actions, effervescent, chewable, buccal, sublingual, molded/tablet triturates.
To produce proper volume and provide cohesion to the powder, aiding in the transfer of the powder blend into tablets or capsule shells.
Capping refers to the separation of the top or bottom of a tablet from the main body.
To absorb moisture and prevent degradation of the active ingredients.
Through the oral mucosa after dissolving slowly in the mouth, cheek pouch, or under the tongue.
Lightly, to produce a soft tablet.
A special tableting machine.
Entrapment of air during processing.
Hard candy.
Absorption of the dissolved substance.
Approximately 15 minutes.
They are more durable.
Direct compression without special coating.
It acts as a lubricant or glidant.
Atropine sulfate 0.4 mg; homatropine hydrobromide 300 mg.
It rapidly disintegrates in the stomach.
Compounding potent drugs or nitroglycerin.
Approximately 50% larger and heavier.
Drug substance, sodium bicarbonate, citric acid, tartaric acid, and a disintegrator.
To mask undesirable taste.
The specific formulation and intended use of the tablet.
Delayed-action and enteric-coated tablets.
Buccal and sublingual tablets, lozenges, troches, and dental cones.
To hold the ingredients together and maintain tablet integrity.
To compress powder into tablet form.
Tablets that are coated with gelatin, making them easier to swallow.
Powders.
Visual identity, overall appearance, size, shape, color, odor, taste, and surface.
Only increase by about 2% - 3%.
Agents that cannot be destroyed by the stomach, such as fats, fatty acids, and waxes.
On an empty stomach (fasting) rather than after a meal.
Repetabs by Schering or Extentabs by Wyeth.
Pregnant women or those who may become pregnant should not handle crushed or broken tablets.
Special flavored mannitol.
It passes through the GI tract, liver, enters the blood circulation from the portal vein, is distributed to target tissues, and is finally excreted from the body.
Layered tablets like phenylephedrine + ascorbic acid + paracetamol.
Heat stable drugs.
It serves as the die for tablets.
Types of tablets that have a coating of sugar or chocolate for taste and protection.
Picking is the removal of small pieces from the surface of a tablet during handling or packaging.
Sodium lauryl sulfate.
They contain NO disintegrant.
They dissolve slowly in the mouth, cheek pouch, or under the tongue.
Usually, they do not contain disintegrants.
A type of sugar candy containing sugar-based lozenges for immediate release.
Neo-codion sugar-coated tablets.
Tablets that consist of a core tablet surrounded by an outer coat, such as Metformin 500 mg sustained release and Pioglitazone 15 mg.
Higher degree of compression than for tablets.
Benzocaine and dextromethorphan.
They need to be chewed, not swallowed whole.
Tablets coated with a thin layer of polymers, increasing efficiency and reducing bulk.
Aspirin enteric-coated tablets.
To enhance the flow properties of powders.
Mottling is the uneven distribution of color on the surface of a tablet.
To shape and compress the tablet during production.
They can be in semi-solid form.
Tablets that need to be chewed; contain mild effervescent drug complex and flavored mannitol.
Rapidly disintegrating/dissolving dosage form.
Oral, sublingual, buccal, or vaginal administrations.
They are less commonly produced compared to other types.
NaHCO3 + R-COOH → RCOONa + H2O + CO2↑
It serves as the punch for tablets.
Croscarmellose.
Sticking occurs when tablets adhere to the punch faces during compression.
To improve taste and patient compliance.
Tablets that are coated with a thin layer of polymer to protect the active ingredients and mask taste.
They provide rapid drug effects and are useful for drugs destroyed by gastric juice.
A tablet that releases gas when dissolved; example: Alka-Seltzer.
Tablets formed by compressing powdered ingredients.
Diluent/filler, disintegrants, lubricants/glidants, and wetting agents.
Tablets coated with sugar for taste and protection.
Tablets that are 1/3 smaller than capsules filled with the same ingredients, making them easier to swallow.
To facilitate the breakup of the tablet in the digestive tract.
Tablets that have a thin film coating for protection and ease of swallowing.
Tablets designed to release their active ingredient in multiple phases over time.
Forms of medication that are solid, such as powders, capsules, tablets, and lozenges.
Lollipops.
Tablets that are formed by molding a mixture of active ingredients and excipients, often used for small doses.
Original tablets → Seal coating (waterproofing) → Subcoating → Syrup coating → Polishing.
Humid storage or contact with wet hands.
Flavored syrup.
Lactose.
Lamination is the formation of layers on the surface of a tablet, which can affect its integrity.
Tablets that are compressed multiple times to achieve specific release characteristics.
Because they are effective for drugs destroyed by gastric juice or poorly absorbed from the intestinal tract (first-pass effect).
Lozenges.
No, they do not contain disintegrants.
To enhance drug dissolution, especially when magnesium stearate is used as a lubricant.
Tablets that are formed by compressing powdered ingredients, including standard and multiple types.
Tablets placed under the tongue for absorption; example: nitroglycerin.
Tablets that are designed to be chewed before swallowing, often flavored for palatability.
Tablets that are coated with a layer of sugar or chocolate to improve taste and appearance.
Tablets designed to release their active ingredients at a specific time or in the intestine.
Tablets that dissolve in the mouth, either between the gum and cheek (buccal) or under the tongue (sublingual) for quick absorption.
Tablets that dissolve in water, releasing carbon dioxide and creating a fizzy solution.
Tablets.
A soft, small, molded tablet that can be compounded.
