1-4 weeks.
Recurrent aphthous ulcers, genital ulcerations, uveitis, and erythema nodosum.
Iodine-induced hyperthyroidism occurring after iodine IV contrast or amiodarone use.
Triad of arthralgias, abdominal pain, and palpable purpura on buttocks/legs.
'Waiter's tip' due to injury to the upper trunk of the brachial plexus.
Commonly presents between 5-7 years.
A reabsorption defect in the thick ascending loop of Henle affecting Na+/K+/2Cl- cotransporter.
Graves Disease.
Immunoglobulin A Vasculitis (formerly called Henoch-Schonlein purpura).
Decreased blood flow to skin due to arteriolar vasospasm in response to cold or stress.
Multiple intestinal polyps, mucocutaneous pigmentation, and tumors of the ovary, breast, and pancreas.
Multiple seborrheic keratoses associated with GI and other visceral malignancies.
Inferior frontal gyrus of the frontal lobe.
Antibodies against presynaptic calcium channels at the NMJ associated with SCLC.
Arachnodactyly, lens dislocation, aortic dissection, and hyperflexible joints.
Von Willebrand disease.
A constellation of clinical features resulting from chronic exposure to excess glucocorticoids.
47,XXY.
An overuse injury caused by repetitive strain and chronic avulsion of the secondary ossification center of the proximal tibial tubercle.
TEN is a more severe form involving >30% body surface area.
Affects small vessels and can cause hemorrhagic intraparenchymal hemorrhage.
Autosomal recessive defect in adhesion due to defective Gplb.
Alzheimer disease.
Reed-Sternberg cells, which are CD15+ and CD30+.
Primary adrenal insufficiency, most commonly due to autoimmune adrenalitis.
FAP or Lynch syndrome, along with malignant brain tumors.
A reabsorption defect in the proximal convoluted tubule leading to excretion of amino acids, glucose, and other substances.
Pruritus, erythema, crusting, and ulcers.
Fibrinous pericarditis post-myocardial infarction.
Pharyngoesophageal false diverticulum.
Sheets of lymphocytes with interspersed 'tingible body' macrophages.
Multiple polyps in the intestines, osteomas, fibromas, and congenital hypertrophy of the retinal pigment epithelium.
Rapidly progressive dementia.
Transmural inflammation with skip lesions, affecting any part of the GI tract.
Defective migration of neurons leading to decreased synthesis of GnRH, hyposmia/anosmia, and infertility.
Weak upper extremity pulses, fever, night sweats, arthritis, myalgias.
Autosomal dominant trinucleotide (CAG) repeat expansion in the HTT gene on chromosome 4.
Defective Gpllb/llla leading to decreased platelet-to-platelet aggregation.
An autosomal dominant hereditary condition characterized by telangiectasias and arteriovenous malformations.
Visual hallucinations, fluctuating cognition, REM sleep behavior disorder, and parkinsonism.
Lack of ganglion cells/enteric nervous plexuses in the distal segment of the colon.
Adverse drug reactions.
Episodic hematuria occurring with respiratory or GI tract infections.
Heavy tobacco smoking history, primarily in males under 40 years old.
X-linked recessive frameshift mutation of the dystrophin gene.
Paradoxical increase in JVP on inspiration, seen in constrictive pericarditis and other conditions.
HSV or parvovirus.
Severe peptic ulcer disease due to unregulated gastrin release from gastrinomas.
Ptosis, anhidrosis, and miosis.
Adhesions and/or fibrosis of the endometrium, often after dilation and curettage.
Situs inversus, chronic ear infections, sinusitis, bronchiectasis, and infertility.
Confusion, ophthalmoplegia, and ataxia.
Deficiency of Th17 cells leading to defective neutrophils, recurrent cold abscesses, eczema, and increased eosinophils and serum IgE.
Megacolon, megaesophagus, and unilateral periorbital swelling (Romana sign).
Short stature and ovarian dysgenesis.
Hypogammaglobulinemia.
A condition that may present as primary amenorrhea due to a lack of uterine development.
Loss of function mutation of sodium channels.
Prolonged QRS duration due to slow conduction through the accessory pathway.
Autoimmune hypothyroidism with germinal centers and fibrosis.
Chronic alcohol overuse.
Mutation in the WAS gene.
Testicular atrophy, tall stature with eunuchoid proportions, gynecomastia, and female hair distribution.
Mildly decreased UDP-glucuronosyltransferase conjugation, leading to asymptomatic or mild jaundice.
'Onion skin' periosteal reaction.
Migratory superficial thrombophlebitis.
G6PD deficiency, leading to bite cells.
A group of progressive hereditary nerve disorders related to defective protein production affecting peripheral nerves or the myelin sheath.
Birbeck granules are 'tennis racket' or rod-shaped structures seen in Langerhans cell histiocytosis.
Autoimmune-mediated intolerance of gliadin, leading to gluten sensitivity.
Turner syndrome (45,XO).
Eye problems, glomerulonephritis, and sensorineural deafness.
Conjunctival injection, rash, cervical adenopathy, strawberry tongue, hand-foot changes, and fever.
Persistence of the vitelline (omphalomesenteric) duct.
Deletion of the VHL gene on chromosome 3p.
Infection with Tropheryma whipplei, causing cardiac, arthralgias, and neurologic symptoms.
Conjugated hyperbilirubinemia due to defective liver excretion.
Basophilic nuclear remnants removed by splenic macrophages, associated with functional hyposplenia.
Calf pseudohypertrophy and Gowers' sign.
Neurofibrillary tangles and Hirano bodies.
Ectopic acid-secreting gastric mucosa and/or pancreatic tissue.
Bell palsy, usually after HSV reactivation.
White (ischemia) to blue (hypoxia) to red (reperfusion).
Absent UDP-glucuronosyltransferase, presenting early in life.
Copper accumulation in liver, brain, cornea, and kidneys.
Right ventricular hypertrophy, overriding aorta, and VSD.
IgM.
Both pupils dilate instead of constrict when light is swung to the affected eye.
Mad cow disease.
Sjogren syndrome.
Tremor, rigidity, akinesia, postural instability, shuffling gait, and micrographia.
Displacement of the tricuspid valve downward into the RV, associated with lithium exposure in utero.
Impaired language comprehension with lack of insight.
HGPRT deficiency, X-linked recessive.
Type V collagen defect.
Becker is less severe and involves slow, progressive muscle weakness.
Antibodies against postsynaptic Ach receptors at the NMJ associated with thymoma.
Chorea, athetosis, aggression, depression, and dementia.
Conversion of an initial left to right shunt into a right to left shunt.
