What does a reservoir of infection represent?
A pool of organisms that can infect humans.
Can you name a common vector for zoonotic infections?
Mosquitoes, ticks, and fleas.
1/291
p.29
Reservoirs of Infection

What does a reservoir of infection represent?

A pool of organisms that can infect humans.

p.53
Zoonotic Diseases

Can you name a common vector for zoonotic infections?

Mosquitoes, ticks, and fleas.

p.3
Definitions of Endemic, Epidemic, and Pandemic

What is the definition of an epidemic?

A marked temporary increase in the occurrence of a disease.

p.61
Zoonotic Diseases

Does Avian influenza Type A normally infect humans?

No, it does not normally infect humans.

p.60
Zoonotic Diseases

What are the most common wild animal sources of rabies?

Raccoons, skunks, bats, and foxes.

p.43
Direct vs. Indirect Spread of Infection

What is transplacental transmission?

Transmission from mother to fetus.

p.37
Reservoirs of Infection

What is the difference between a reservoir and a source of infection?

A reservoir is the natural habitat where an infectious agent lives and multiplies, while a source of infection is the specific location or organism from which the infection is transmitted to a host.

p.8
Principles of Epidemiology

How can tetanus be prevented?

By vaccination.

p.11
Mechanisms of Disease Transmission

Why is cross infection significant in hospitals?

It is an important transmission route.

p.38
Mechanisms of Disease Transmission

What is direct contact transmission?

Transmission of infectious disease through physical contact between an infected person and a susceptible person.

p.2
Principles of Epidemiology

What is epidemiology?

The study of the occurrence and distribution of disease.

p.37
Reservoirs of Infection

Can a reservoir and a source of infection sometimes be the same?

Yes, they can sometimes be the same, as an organism can serve both as a habitat for the infectious agent and as the source of infection for a host.

p.42
Types of Infectious Diseases

Which virus is responsible for genital herpes?

Herpes Simplex II.

p.52
Mechanisms of Disease Transmission

How far can airborne particles travel?

They can travel more than 1 meter.

p.18
Pathogenicity and Virulence

What is the ability to convert to an endospore?

A virulence factor that allows bacteria to survive harsh conditions.

p.25
Types of Infectious Diseases

What is a major consequence of polio virus infection?

Paralysis of related muscles.

p.49
Mechanisms of Disease Transmission

What is a fomite?

Any non-living object that can be a source of infection.

p.21
Pathogenicity and Virulence

What are endotoxins?

Lipopolysaccharides (LPS) from the outer cell membrane of Gram-negative cells.

p.58
Types of Infectious Diseases

What is anthrax commonly known for?

Being used as a biological weapon.

p.16
Pathogenicity and Virulence

What does host susceptibility depend on?

The individual's health and their immune response.

p.52
Mechanisms of Disease Transmission

What are airborne particles?

Small droplets that have evaporated, typically less than 5 micrometers in diameter, released during talking, sneezing, and coughing.

p.32
Types of Infectious Diseases

What condition does Clostridium tetani cause?

Tetanus, characterized by muscle stiffness and spasms.

p.26
Chain of Infection

What follows the pathogen leaving its reservoir in the chain of infection?

It is conveyed by some mode of transmission.

p.48
Routes of Transmission

What is a common source of infection in untreated water?

Contamination with sewage.

p.3
Definitions of Endemic, Epidemic, and Pandemic

What is the definition of an endemic disease?

A disease that is always present within a community.

p.48
Types of Infectious Diseases

What type of organism is Giardia lamblia?

A protozoan (single-celled parasite).

p.45
Mechanisms of Disease Transmission

How can indirect contact lead to infection?

Pathogens can survive on surfaces and be transferred to a person who touches them.

p.16
Pathogenicity and Virulence

How does normal bacterial flora protect the host?

By preventing colonization by bacterial pathogens.

p.31
Pathogenicity and Virulence

What is the shape and classification of Clostridium tetani?

Large gram-positive rods.

p.18
Pathogenicity and Virulence

What role do flagella play in bacteria?

They provide motility, allowing bacteria to move towards favorable environments.

p.24
Chain of Infection

What follows the pathogen leaving its reservoir in the chain of infection?

It is conveyed by some mode of transmission.

p.51
Mechanisms of Disease Transmission

What is droplet transmission?

The spread of pathogens in infectious droplets greater than 5 mm in diameter that travel a short distance (about 1 meter).

p.18
Pathogenicity and Virulence

What is the purpose of a polysaccharide capsule in bacteria?

It helps in evading immune cells, enhancing bacterial survival.

p.36
Types of Infectious Diseases

Who is an example of a famous asymptomatic carrier?

Typhoid Mary.

p.53
Zoonotic Diseases

What role do environmental factors play in zoonotic infections?

They can influence the population and behavior of vectors, affecting disease transmission.

p.36
Mechanisms of Disease Transmission

What is the significance of asymptomatic carriage?

It highlights how individuals can spread infections without showing symptoms.

p.1
Direct vs. Indirect Spread of Infection

What is the difference between direct and indirect spread of infection?

Direct spread involves immediate transfer of pathogens, while indirect spread involves transmission through an intermediary.

p.12
Chain of Infection

What occurs during the second stage of infection development?

Adhesion to host cells (attach to host cells).

p.63
Direct vs. Indirect Spread of Infection

What is one example of a disease spread by direct contact?

Chickenpox.

p.47
Routes of Transmission

What type of transmission occurs when food handlers spread infection via their hands?

Fecal-oral transmission.

p.41
Types of Infectious Diseases

What is a communicable disease?

An infectious disease that can be transmitted from one human to another.

p.41
Routes of Transmission

How are communicable diseases transmitted?

From person to person.

p.54
Mechanisms of Disease Transmission

What is a vector in the context of arthropod-borne infections?

An arthropod that carries a pathogen from one host to another.

p.43
Types of Infectious Diseases

Which virus is an example of transplacental transmission?

German measles (Rubella virus).

p.50
Chain of Infection

What risk do the hands of healthcare workers pose?

They may cause cross infection as they move from patient to patient.

p.2
Principles of Epidemiology

What are the key aspects studied in epidemiology?

Occurrence, distribution, risk factors, and transmission prevention of diseases.

p.6
Pathogenicity and Virulence

What type of pathogen causes a wide range of different diseases?

Staphylococcus aureus.

p.61
Zoonotic Diseases

Can Avian influenza Type A infect domestic poultry?

Yes, it can infect domestic poultry and other birds.

p.18
Pathogenicity and Virulence

What is the function of pili (fimbriae) in bacteria?

They are used for attachment to surfaces or host cells.

p.17
Pathogenicity and Virulence

What are virulence factors?

Physical structures or chemical substances that enhance the pathogen's ability to cause disease.

p.53
Zoonotic Diseases

How do vectors contribute to the spread of zoonotic diseases?

By carrying and transmitting pathogens between animals and humans.

p.17
Pathogenicity and Virulence

What are some examples of virulence factors?

Ability to produce toxins and presence of extracellular enzymes.

p.10
Pathogenicity and Virulence

What is a common source of endogenous infections?

Normal flora that can become pathogenic under certain conditions.

p.12
Chain of Infection

What is the first stage in the development of infection?

Acquisition (the pathogen gets into the body).

p.63
Direct vs. Indirect Spread of Infection

What is another example of a disease spread by direct contact?

HIV/AIDS.

p.11
Mechanisms of Disease Transmission

What is an exogenous infection?

An infection caused by the transfer of microbes from one person to another.

p.32
Types of Infectious Diseases

What is Clostridium tetani?

A bacterium that causes tetanus.

p.50
Mechanisms of Disease Transmission

What can happen when contaminated hands touch another surface or person?

Pathogens can be transferred to that surface or person.

p.16
Pathogenicity and Virulence

What role does the virulence of an organism play?

It affects the pathogenicity of the bacteria.

p.29
Reservoirs of Infection

Can the reservoir be the source of the pathogen for the human host?

The reservoir may or may not be the source of the pathogen for the human host.

p.32
Routes of Transmission

How does Clostridium tetani enter the human body?

Through contaminated wounds or injuries.

p.36
Types of Infectious Diseases

What is a carrier in the context of infectious diseases?

A person who is colonized with the organism and can transmit the pathogen to others.

p.26
Chain of Infection

What is the sequence of events in the chain of infection called?

The chain of infection.

p.20
Mechanisms of Disease Transmission

What is one way tissue damage occurs?

Release of enzymes that can kill cells, such as collagenase and protease.

p.33
Sources of Infection

What is often the source of pathogens in a healthcare setting?

The patient themselves, their body fluids, or skin lesions.

p.21
Pathogenicity and Virulence

What happens when a Gram-negative cell dies?

Endotoxins are released, which are highly toxic to certain human tissues.

p.34
Types of Infectious Diseases

What is Salmonella typhi?

A bacterium that can cause typhoid fever.

p.47
Types of Infectious Diseases

Which bacteria are commonly found in raw chicken?

Salmonella and Campylobacter.

p.11
Mechanisms of Disease Transmission

What is another term for exogenous infection?

Cross infection.

p.11
Mechanisms of Disease Transmission

How is cross infection often transmitted in a hospital environment?

Often via the hands of healthcare workers.

p.32
Routes of Transmission

What are the portals of entry for Clostridium tetani in humans?

Typically through wounds or punctures in the skin.

p.29
Reservoirs of Infection

What are some examples of reservoirs of infection?

Soil, dust, contaminated water, contaminated food, insects, infected humans or animals, and wild animals.

p.25
Mechanisms of Disease Transmission

What factors influence the effect of a viral infection?

The location of the cell and the type of virus.

p.3
Definitions of Endemic, Epidemic, and Pandemic

Give an example of an epidemic.

A food poisoning outbreak or influenza.

p.52
Mechanisms of Disease Transmission

What happens to airborne particles after they are released?

They dry into dust.

p.6
Pathogenicity and Virulence

Which microorganism is known for causing tetanus?

Clostridium tetani.

p.53
Zoonotic Diseases

What is a zoonotic infection?

An infection that is transmitted from animals to humans.

p.49
Mechanisms of Disease Transmission

Give examples of fomites.

Cups, dishes, cutlery, trays, cleaning cloths, medical instruments, towels, bedding, thermometers, contaminated syringes, door knobs, computer keyboards, toys.

p.19
Pathogenicity and Virulence

What is an exotoxin?

A toxin that is secreted by bacteria into their environment, often causing damage to host cells.

p.1
Chain of Infection

What should one be able to discuss regarding infectious diseases?

Routes of transmission and ways to break the chain of transmission.

p.47
Routes of Transmission

How can food handlers contribute to food-borne transmission?

By not practicing good hand hygiene, especially if suffering from gastroenteritis.

p.58
Types of Infectious Diseases

When was anthrax notably used as a biological weapon?

After September 11, 2001.

p.29
Reservoirs of Infection

What is a reservoir of infection?

The site where the microorganism usually lives, which may be in the environment, animals, or humans.

p.38
Mechanisms of Disease Transmission

What is indirect contact transmission?

Transmission of infectious disease through an intermediary object or organism, such as contaminated surfaces or vectors.

p.2
Principles of Epidemiology

What does epidemiology help us understand?

Who is at risk, how disease spreads, and how transmission may be prevented.

p.31
Types of Infectious Diseases

What bacterium causes Tetanus (Lockjaw)?

Clostridium tetani.

p.53
Zoonotic Diseases

What are vectors in the context of zoonotic infections?

Organisms that transmit pathogens from one host to another.

p.10
Types of Infectious Diseases

What is an exogenous infection?

An infection that originates from outside the body.

p.36
Types of Infectious Diseases

What does it mean for a carrier to be colonized?

It means the carrier hosts the organism without showing symptoms.

p.6
Pathogenicity and Virulence

What are opportunistic pathogens?

Pathogens that only attack those who are weaker, chronically ill, or immunocompromised.

p.23
Principles of Epidemiology

What is the purpose of a Gram stain?

To classify bacteria based on their cell wall characteristics.

p.31
Types of Infectious Diseases

What is a major symptom caused by the neurotoxin of Clostridium tetani?

Muscle spasms.

p.23
Types of Infectious Diseases

What are the two main types of bacteria identified by Gram staining?

Gram-positive and Gram-negative.

p.5
Types of Infectious Diseases

What are notifiable diseases?

Diseases that doctors are required by law to report.

p.34
Pathogenicity and Virulence

How long can patients who have recovered from Salmonella typhi remain colonized?

For months or years.

p.5
Types of Infectious Diseases

How many notifiable infectious diseases are there in Hong Kong?

At least 50, including Chicken pox and cholera.

p.34
Reservoirs of Infection

Where does Salmonella typhi stay in chronic carriers?

In the gall bladder or kidneys.

p.21
Pathogenicity and Virulence

What is the mortality rate associated with endotoxic shock?

Approximately 50%.

p.28
Chain of Infection

What is the route of exit in the chain of infection?

How the pathogen escapes from the reservoir.

p.57
Mechanisms of Disease Transmission

How is Anthrax spread?

Contact with infected animal products.

p.57
Zoonotic Diseases

What is the cause of Avian Influenza?

Virus (H5N1).

p.47
Mechanisms of Disease Transmission

What can improperly cooked or stored food lead to?

Gastrointestinal pathogens.

p.4
Definitions of Endemic, Epidemic, and Pandemic

Can you give an example of a pandemic?

The 1918 Spanish flu, which killed over 20 million worldwide.

p.50
Mechanisms of Disease Transmission

How can hands become contaminated with pathogens in a healthcare setting?

By contact with contaminated surfaces, patient excretions, secretions, or open skin lesions.

p.25
Mechanisms of Disease Transmission

What can viral infections do to a cell?

They can kill a cell or stop its function.

p.54
Mechanisms of Disease Transmission

Which arthropods are commonly known as vectors of disease?

Mosquitoes, flies, lice, ticks, etc.

p.40
Direct vs. Indirect Spread of Infection

What are some examples of direct contact?

Touching, kissing, and sexual intercourse.

p.61
Zoonotic Diseases

What type of birds naturally carry Avian influenza Type A?

Wild aquatic birds.

p.24
Chain of Infection

What is the first step in the chain of infection?

The pathogen leaves its reservoir or host through a portal of exit.

p.23
Pathogenicity and Virulence

What is the primary component of bacterial cell walls?

Peptidoglycan.

p.46
Mechanisms of Disease Transmission

What are vehicles in the context of disease transmission?

Objects or materials that can carry pathogens to a host.

p.24
Chain of Infection

What is the final step for a pathogen in the chain of infection?

It enters through an appropriate portal of entry to infect a susceptible host.

p.15
Pathogenicity and Virulence

How is virulence expressed?

As the ratio of individuals developing clinical illness to those exposed to the microbe.

p.46
Mechanisms of Disease Transmission

How can contaminated food act as a vehicle for disease?

By harboring pathogens that can infect individuals when consumed.

p.28
Chain of Infection

What is the first step to break the chain of infection?

Identify the pathogen.

p.46
Mechanisms of Disease Transmission

What role does water play as a vehicle for disease transmission?

It can carry pathogens that cause waterborne diseases.

p.13
Mechanisms of Disease Transmission

What is the second step in the process of infection?

Adhesion.

p.27
Chain of Infection

What is the Chain of Infection?

A model that explains how infections are transmitted from one host to another.

p.35
Types of Infectious Diseases

What can asymptomatic carriers of Neisseria meningitidis cause?

They can be a source of infection for others, potentially leading to meningococcal meningitis.

p.55
Zoonotic Diseases

What type of pathogen causes Dengue fever?

Virus.

p.35
Types of Infectious Diseases

Where can Staphylococcus aureus be found in asymptomatic carriers?

In the nose.

p.27
Chain of Infection

What does the portal of exit refer to?

The path by which an infectious agent leaves its reservoir.

p.57
Mechanisms of Disease Transmission

How is Rabies spread?

Bite of infected animal.

p.30
Types of Infectious Diseases

What disease is caused by Rotavirus?

Gastroenteritis.

p.47
Types of Infectious Diseases

What illness can Salmonella and Campylobacter cause?

Gastroenteritis.

p.8
Mechanisms of Disease Transmission

What type of toxin does Clostridium tetani produce?

A neurotoxin.

p.43
Direct vs. Indirect Spread of Infection

What is another term for transplacental transmission?

Vertical transmission.

p.42
Types of Infectious Diseases

What is the causative agent of gonorrhea?

Neisseria gonorrhoeae.

p.40
Direct vs. Indirect Spread of Infection

What is direct contact transmission?

Direct transmission between the source of infection and a susceptible host through physical contact.

p.43
Types of Infectious Diseases

What is a notable example of HIV transmission?

Transplacental transmission from mother to fetus.

p.25
Types of Infectious Diseases

Which type of cells does the polio virus infect?

Nerve cells.

p.26
Chain of Infection

What is the final step in the chain of infection?

The pathogen enters through an appropriate portal of entry to infect a susceptible host.

p.31
Mechanisms of Disease Transmission

What type of spores does Clostridium tetani form?

Endospores.

p.19
Pathogenicity and Virulence

What is an endotoxin?

A toxin that is part of the outer membrane of certain bacteria and is released when the bacteria die.

p.34
Reservoirs of Infection

What are human carriers in the context of infectious diseases?

Important living reservoirs of infectious disease.

p.5
Types of Infectious Diseases

Can you give examples of sporadic diseases?

Typhoid fever, botulism, cholera, whooping cough.

p.51
Mechanisms of Disease Transmission

How is droplet transmission commonly initiated?

By coughing, sneezing, or talking.

p.33
Sources of Infection

Can infections come from patients who are recovering?

Yes, infections may come from patients who are sick or recovering.

p.19
Pathogenicity and Virulence

What does 'LA' refer to in the context of toxins?

It is unclear without additional context; it may refer to a specific toxin or laboratory abbreviation.

p.17
Pathogenicity and Virulence

What role do exotoxins play in virulence?

They are toxic substances produced by pathogens that can damage host tissues.

p.10
Principles of Epidemiology

Can endogenous infections be prevented?

They are harder to prevent, but maintaining a healthy immune system can help.

p.57
Zoonotic Diseases

What animal is a host for Anthrax?

Cattle.

p.56
Mechanisms of Disease Transmission

How can zoonotic pathogens be inhaled or ingested?

By inhalation or ingestion of the pathogen.

p.56
Mechanisms of Disease Transmission

What role do arthropod vectors play in zoonotic diseases?

They can inject the pathogen into humans.

p.39
Mechanisms of Disease Transmission

What is vector-borne transmission?

Transmission of pathogens through vectors like insects or animals.

p.56
Mechanisms of Disease Transmission

What is another method of transmission for zoonotic diseases?

Inhalation of bacterial spores.

p.55
Zoonotic Diseases

What is the causative organism of Bubonic plague?

Yersinia pestis.

p.8
Types of Infectious Diseases

What disease is caused by Clostridium tetani?

Tetanus (Lockjaw).

p.45
Mechanisms of Disease Transmission

What is indirect contact in the context of disease transmission?

Transmission of pathogens through an intermediate object or organism.

p.3
Definitions of Endemic, Epidemic, and Pandemic

Give an example of an endemic disease.

Common cold or Athlete’s foot.

p.26
Chain of Infection

What is the first step in the chain of infection?

The pathogen leaves its reservoir or host through a portal of exit.

p.6
Pathogenicity and Virulence

What is pathogenicity?

The ability of a microorganism to cause disease in the host.

p.45
Mechanisms of Disease Transmission

What role do fomites play in indirect contact transmission?

Fomites are inanimate objects that can carry pathogens and facilitate indirect transmission.

p.54
Mechanisms of Disease Transmission

What diseases are transmitted by mosquitoes?

Malaria and Dengue fever.

p.9
Pathogenicity and Virulence

What are opportunistic pathogens?

Weak pathogens that only cause disease in individuals with impaired immunity.

p.31
Pathogenicity and Virulence

What type of toxin does Clostridium tetani produce?

A neurotoxin.

p.61
Mechanisms of Disease Transmission

How do infected birds shed the avian influenza virus?

In their saliva, mucous, and feces.

p.46
Mechanisms of Disease Transmission

Can you give examples of vehicles that transmit disease?

Food, water, and inanimate objects like utensils.

p.61
Routes of Transmission

What can lead to human infection from Avian influenza?

Close contact with infected poultry or surfaces contaminated by poultry.

p.21
Pathogenicity and Virulence

What condition can be caused by endotoxins leading to severe symptoms?

Septic (endotoxic) shock.

p.23
Mechanisms of Disease Transmission

What color do Gram-positive bacteria appear after staining?

Purple.

p.35
Types of Infectious Diseases

What are asymptomatic carriers?

Healthy individuals who carry a pathogenic organism without showing illness or symptoms.

p.57
Zoonotic Diseases

What is the cause of Anthrax?

Bacillus anthracis (endospore former).

p.7
Types of Infectious Diseases

What type of infections can Staphylococcus aureus cause?

Skin and soft tissue infections, food poisoning, toxic shock syndrome, scalded skin syndrome, acute endocarditis, surgical site infections, pneumonia, osteomyelitis, and septicaemia.

p.15
Pathogenicity and Virulence

What are the characteristics of the Ebola virus?

It is very infectious, very pathogenic, and very virulent, often causing severe and fatal disease.

p.13
Mechanisms of Disease Transmission

What is the fourth step in the process of infection?

Multiplication.

p.13
Mechanisms of Disease Transmission

What is the fifth step in the process of infection?

Damage to tissues.

p.55
Zoonotic Diseases

What is the insect vector for Malaria?

Mosquito.

p.55
Zoonotic Diseases

What is the causative organism of Malaria?

Plasmodium falciparum.

p.39
Mechanisms of Disease Transmission

What are fomites?

Inanimate objects that can carry and transmit infectious agents.

p.30
Types of Infectious Diseases

Which microorganism is associated with Typhoid fever?

Salmonella typhi.

p.30
Types of Infectious Diseases

What disease is caused by pathogenic strains of E. coli?

Gastroenteritis.

p.30
Types of Infectious Diseases

What disease is caused by Salmonella species?

Gastroenteritis.

p.62
Zoonotic Diseases

What is a risk factor for infection related to poultry?

Close contact with infected poultry.

p.4
Definitions of Endemic, Epidemic, and Pandemic

What is a pandemic?

An epidemic that affects communities throughout the world.

p.47
Mechanisms of Disease Transmission

What is post-cooking contamination?

Contamination of cooked food by contact with uncooked food.

p.42
Types of Infectious Diseases

What bacterium causes syphilis?

Treponema pallidum.

p.48
Types of Infectious Diseases

What disease is caused by Vibrio cholerae?

Cholera.

p.45
Mechanisms of Disease Transmission

Give an example of indirect contact transmission.

Touching contaminated surfaces or objects, such as doorknobs or utensils.

p.48
Types of Infectious Diseases

What disease is associated with Giardia lamblia?

Diarrheal disease.

p.42
Routes of Transmission

What type of contact is primarily responsible for the transmission of sexually transmitted diseases?

Direct contact.

p.16
Pathogenicity and Virulence

What surfaces are associated with normal bacterial flora?

Skin and mucosal surfaces.

p.52
Types of Infectious Diseases

Which infections are commonly spread through airborne particles?

Tuberculosis, Measles, and Chicken pox.

p.5
Types of Infectious Diseases

What is a sporadic disease?

A disease that only occurs occasionally in a particular region.

p.1
Principles of Epidemiology

What is the focus of epidemiology in relation to infectious diseases?

Understanding the principles of epidemiology.

p.6
Pathogenicity and Virulence

What is the classification of bacteria that do not cause disease?

Not pathogens.

p.49
Mechanisms of Disease Transmission

Where are fomites often a source of infection?

In hospitals.

p.19
Pathogenicity and Virulence

What is an enterotoxin?

A type of exotoxin that specifically targets the intestines, often causing gastrointestinal symptoms.

p.51
Mechanisms of Disease Transmission

What distinguishes droplet transmission from airborne transmission?

Droplet transmission involves larger droplets that travel shorter distances, while airborne transmission involves smaller particles that can travel longer distances.

p.10
Principles of Epidemiology

Can exogenous infections be prevented?

Yes, through hygiene and vaccination.

p.51
Types of Infectious Diseases

Which diseases are commonly associated with droplet transmission?

Influenza, whooping cough (pertussis), SARS, COVID-19, and MERS.

p.35
Types of Infectious Diseases

Which organism is an example of an asymptomatic carrier in the upper respiratory tract?

Neisseria meningitidis (meningococcus).

p.23
Pathogenicity and Virulence

What does a Gram stain help to determine about bacteria?

The structure of their cell wall.

p.12
Chain of Infection

What happens in the fourth stage of infection development?

Multiplication in tissues.

p.12
Chain of Infection

What is the fifth stage in the development of infection?

Damage to tissues.

p.57
Zoonotic Diseases

What animal is a host for Avian Influenza?

Birds.

p.39
Mechanisms of Disease Transmission

How can food and water lead to disease transmission?

Through contamination with pathogens.

p.57
Zoonotic Diseases

What animals are common hosts for Rabies?

Infected wild dogs, bats, raccoons.

p.30
Reservoirs of Infection

Which microorganism is associated with water as an environmental reservoir?

Legionella pneumophila.

p.54
Mechanisms of Disease Transmission

How can flies contribute to the spread of disease?

By carrying feces on their feet or body parts to food, such as houseflies carrying Salmonella typhi.

p.40
Types of Infectious Diseases

What types of diseases can be transmitted through direct contact?

Viral respiratory tract diseases like common cold and influenza, MRSA, measles, chicken pox, and mumps.

p.5
Definitions of Endemic, Epidemic, and Pandemic

What does the mortality rate refer to?

The number of deaths due to a particular disease in a given period relative to the total population.

p.10
Types of Infectious Diseases

What is an endogenous infection?

An infection that originates from within the body, often from normal flora.

p.36
Mechanisms of Disease Transmission

How can carriers impact the spread of infection?

They can serve as a source of pathogens for infecting others.

p.10
Mechanisms of Disease Transmission

How do exogenous infections typically enter the body?

Through external sources such as pathogens from the environment.

p.24
Chain of Infection

What is the sequence of events in the chain of infection called?

The chain of infection.

p.9
Pathogenicity and Virulence

What is the classification of Pseudomonas aeruginosa?

It is a gram-negative rod.

p.22
Mechanisms of Disease Transmission

How does enterotoxin differ from other exotoxins?

Enterotoxin specifically targets the enteral (intestinal) system, while other exotoxins may affect various tissues.

p.39
Mechanisms of Disease Transmission

What is droplet transmission?

Spread of pathogens through respiratory droplets when an infected person coughs or sneezes.

p.21
Pathogenicity and Virulence

Which type of bacteria is more likely to cause fatal septicemia?

Gram-negative bacteria.

p.35
Types of Infectious Diseases

Which other organisms can be carried asymptomatically?

Streptococcus pneumoniae, Staphylococcus aureus, and MRSA.

p.7
Types of Infectious Diseases

What is scalded skin syndrome?

A condition caused by Staphylococcus aureus that leads to skin peeling and blistering.

p.56
Types of Infectious Diseases

Who is considered the highest risk group for zoonotic diseases?

Veterinary surgeons, farmers, and slaughterhouse workers.

p.7
Types of Infectious Diseases

What type of bone infection can be caused by Staphylococcus aureus?

Osteomyelitis.

p.55
Zoonotic Diseases

What type of pathogen causes Bubonic plague?

Bacterium.

p.30
Reservoirs of Infection

What is an example of an animal reservoir and its associated microorganism?

Cattle; E. coli (pathogenic strains).

p.9
Pathogenicity and Virulence

Give an example of an opportunistic pathogen.

Pseudomonas aeruginosa.

p.22
Mechanisms of Disease Transmission

What is an exotoxin?

A toxic substance secreted by bacteria into their environment, often causing damage to host cells.

p.20
Mechanisms of Disease Transmission

What are exotoxins?

Proteins produced by bacteria and excreted into the local environment.

p.9
Pathogenicity and Virulence

What is another example of an opportunistic pathogen?

Candida albicans.

p.22
Mechanisms of Disease Transmission

What is an enterotoxin?

A type of exotoxin that specifically targets the intestinal tract, causing gastrointestinal symptoms.

p.56
Zoonotic Diseases

What are zoonotic diseases?

Infections picked up from animals through various means.

p.15
Pathogenicity and Virulence

How do different influenza viruses vary in terms of virulence?

Some cause mild symptoms while others can be very severe and cause death.

p.9
Pathogenicity and Virulence

Who is most at risk from opportunistic pathogens?

Individuals with impaired immunity.

p.55
Zoonotic Diseases

What is the insect vector for Dengue fever?

Mosquito.

p.33
Mechanisms of Disease Transmission

Can patients recovering from typhoid fever be infectious?

Yes, they can be infectious even after recovery.

p.55
Zoonotic Diseases

What is the causative organism of Dengue fever?

Flavivirus.

p.7
Types of Infectious Diseases

What serious heart condition can Staphylococcus aureus cause?

Acute endocarditis.

p.7
Types of Infectious Diseases

What is septicaemia?

A condition where the blood is infected, which can be caused by Staphylococcus aureus.

p.15
Pathogenicity and Virulence

What is virulence?

The measurement of pathogenicity of a microbe.

p.9
Pathogenicity and Virulence

What type of infections does Pseudomonas aeruginosa cause?

Healthcare-associated infections.

p.22
Mechanisms of Disease Transmission

What is an endotoxin?

A component of the outer membrane of Gram-negative bacteria that is released when the bacteria die, often causing systemic effects.

p.20
Pathogenicity and Virulence

What is an example of a powerful neurotoxin?

Tetanus toxin from Clostridium tetani.

p.15
Pathogenicity and Virulence

What characterizes highly virulent pathogens?

They are more likely to cause disease in a host.

p.21
Pathogenicity and Virulence

What are common symptoms of septicemia caused by Gram-negative organisms?

High fever and drop in blood pressure.

p.23
Mechanisms of Disease Transmission

What color do Gram-negative bacteria appear after staining?

Pink.

p.56
Routes of Transmission

What is one way zoonotic diseases can be transmitted?

Close (direct) contact with an animal.

p.33
Mechanisms of Disease Transmission

What is the recovery (convalescent) period?

The period when a patient may still be infectious for days or weeks after recovery.

p.28
Chain of Infection

What does the mode of transmission refer to?

How the pathogen is transmitted (e.g., person to person, via animals, via soil).

p.28
Chain of Infection

What is the portal of entry in the chain of infection?

The route through which the pathogen enters the body of a susceptible person.

p.35
Types of Infectious Diseases

Where is MRSA commonly found?

In the hospital.

p.55
Zoonotic Diseases

What type of pathogen causes Malaria?

Protozoa.

p.13
Types of Infectious Diseases

What happens if an infection is systemic?

It can cross into the bloodstream and spread to other parts of the body.

p.27
Chain of Infection

Who is considered a susceptible host?

An individual who is at risk of infection due to factors like weakened immune system or lack of immunity.

p.17
Pathogenicity and Virulence

How do physical structures like pili and capsules contribute to virulence?

They help the pathogen adhere to host tissues and evade the immune response.

p.33
Mechanisms of Disease Transmission

What is the incubation period?

The time between initial infection and the first appearance of symptoms.

p.20
Mechanisms of Disease Transmission

What are enterotoxins?

Exotoxins that target the small intestine, causing vomiting and diarrhea.

p.33
Mechanisms of Disease Transmission

Can a patient be infectious during the incubation period?

Yes, the patient may be infectious but asymptomatic.

p.34
Mechanisms of Disease Transmission

How is Salmonella typhi excreted by carriers?

In faeces and urine.

p.39
Mechanisms of Disease Transmission

What is airborne transmission?

Transmission of pathogens through the air over long distances.

p.39
Mechanisms of Disease Transmission

What does vehicle transmission refer to?

Spread of infection through contaminated inanimate objects, such as food or water.

p.12
Chain of Infection

What occurs during the sixth stage of infection development?

Spread to other tissue (only some infections will spread).

p.57
Mechanisms of Disease Transmission

How is Avian Influenza spread?

Direct or indirect contact with infected birds.

p.39
Mechanisms of Disease Transmission

What role do contaminated hands play in disease transmission?

They can transfer pathogens to surfaces or directly to individuals.

p.30
Types of Infectious Diseases

What disease is caused by Clostridium tetani?

Tetanus.

p.30
Types of Infectious Diseases

What disease is caused by Rhinovirus?

Common cold.

p.49
Mechanisms of Disease Transmission

What types of objects can be considered fomites?

Any non-living objects like medical instruments, towels, and electronic devices.

p.49
Mechanisms of Disease Transmission

Why are fomites significant in healthcare settings?

They are often the source of hospital-acquired infections.

p.46
Mechanisms of Disease Transmission

What is the significance of inanimate objects in disease transmission?

They can become contaminated and transfer pathogens to humans.

p.13
Mechanisms of Disease Transmission

What is the third step in the process of infection?

Penetration of cells.

p.34
Chain of Infection

What can a carrier of Salmonella typhi cause?

An outbreak of infection.

p.34
Types of Infectious Diseases

Who was Typhoid Mary?

A chronic carrier of Salmonella typhi.

p.13
Mechanisms of Disease Transmission

Can infection spread to other tissues?

Yes, it can spread to other tissues.

p.13
Types of Infectious Diseases

What types of infections can occur?

Local (e.g., gastrointestinal) or systemic (cross into bloodstream).

p.57
Zoonotic Diseases

What is the cause of Rabies?

Rabies virus.

p.55
Zoonotic Diseases

What is the insect vector for Bubonic plague?

Rat flea.

p.30
Types of Infectious Diseases

What disease is caused by Legionella pneumophila?

Legionnaires’ disease.

p.30
Reservoirs of Infection

What is a human reservoir found in the gut?

Rotavirus.

p.13
Mechanisms of Disease Transmission

What is the first step in the process of infection?

Acquisition.

p.39
Mechanisms of Disease Transmission

What is indirect contact transmission?

Transmission of infection through contaminated objects or surfaces.

p.1
Definitions of Endemic, Epidemic, and Pandemic

What are the definitions of endemic, epidemic, and pandemic?

Endemic refers to a disease regularly found among particular people or in a certain area; epidemic refers to a sudden increase in the number of cases; pandemic refers to an epidemic that has spread over multiple countries or continents.

p.20
Pathogenicity and Virulence

Which bacterium produces cholera toxin?

Vibrio cholera.

p.7
Types of Infectious Diseases

What is a common skin infection caused by Staphylococcus aureus?

Abscesses.

p.7
Types of Infectious Diseases

What syndrome associated with Staphylococcus aureus can lead to severe complications in women?

Toxic shock syndrome.

p.27
Chain of Infection

What is a reservoir in the context of the Chain of Infection?

The natural habitat where the infectious agent lives and multiplies.

p.39
Zoonotic Diseases

What is zoonotic transmission?

Spread of diseases from animals to humans.

p.7
Types of Infectious Diseases

What type of infection can occur at surgical sites due to Staphylococcus aureus?

Surgical site infections.

p.27
Chain of Infection

What is the portal of entry in the Chain of Infection?

The route through which an infectious agent enters a susceptible host.

p.7
Types of Infectious Diseases

What type of pneumonia can be caused by Staphylococcus aureus?

Pneumonia.

p.30
Reservoirs of Infection

Which microorganism is associated with poultry as an animal reservoir?

Salmonella species.

p.28
Chain of Infection

What must be known about the pathogen to break the chain of infection?

The reservoir or source for the pathogen (e.g., soil, water, other humans).

p.12
Chain of Infection

What is the third stage in the development of infection?

Penetration of cells.

p.27
Chain of Infection

What are the key components of the Chain of Infection?

Infectious agent, reservoir, portal of exit, mode of transmission, portal of entry, and susceptible host.

p.27
Chain of Infection

What is an infectious agent?

A pathogen that can cause disease, such as bacteria, viruses, fungi, or parasites.

p.56
Reservoirs of Infection

What is a common source of zoonotic pathogens in animal products?

Unpasteurized milk.

p.12
Chain of Infection

What are the possible outcomes in the final stage of infection development?

The infection is cured (resolution) or the infected person dies.

p.27
Chain of Infection

What are the modes of transmission in the Chain of Infection?

Ways in which the infectious agent is spread, including direct contact, airborne, vector-borne, and vehicle-borne.

p.30
Reservoirs of Infection

What is an example of an environmental reservoir and its associated microorganism?

Soil; Clostridium tetani.

p.30
Reservoirs of Infection

What is a human reservoir found in the respiratory tract?

Rhinovirus.

p.28
Chain of Infection

Who is considered a susceptible host?

Individuals at risk, such as healthy individuals, immunocompromised persons, children, and the elderly.

p.30
Types of Infectious Diseases

What microorganism causes Cholera?

Vibrio cholerae.

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