What is Hemolytic Anemia?
A condition where red blood cells are destroyed faster than they can be made.
What types of chemicals can lead to hemolysis?
Anticonvulsant and antimalaria drugs.
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Hemolytic Anemia

What is Hemolytic Anemia?

A condition where red blood cells are destroyed faster than they can be made.

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Extrinsic Disorders of RBCs

What types of chemicals can lead to hemolysis?

Anticonvulsant and antimalaria drugs.

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Blood Loss Anemia

What is the primary cause of acute blood loss anemia?

Haemorrhage.

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Aplastic Anemia

What are some causes of Aplastic Anemia?

1. Irradiation 2. Tumors 3. Anticancer drugs.

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Aplastic Anemia

What role do tumors play in Aplastic Anemia?

They can destroy bone marrow.

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Effects of Anemia and Polycythemia on Cardiovascular System

What skin color changes are associated with anemia and polycythemia?

Anemia causes pallor (decreased Hb), while polycythemia leads to cyanosis (increased reduced Hb).

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Polycythemia

What does polycythemia mean?

Increased number of RBCs.

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Definition of Anemia

What is anemia?

A decrease in O2 carrying capacity of blood due to deficiency of hemoglobin (Hb).

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Hemolytic Anemia

What is hemolytic anemia?

A type of anemia caused by the destruction of red blood cells.

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Megaloblastic Anemia

What characterizes megaloblastic anemia?

The presence of large, abnormal red blood cells due to impaired DNA synthesis.

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Polycythemia

What accompanies primary polycythemia vera?

Increased production of WBCs and platelets.

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Aplastic Anemia

How can anticancer drugs lead to Aplastic Anemia?

By damaging the bone marrow.

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Blood Viscosity and Flow Dynamics

How does blood flow velocity differ between anemia and polycythemia?

In anemia, blood flow velocity is increased; in polycythemia, it is decreased.

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Polycythemia

What is the possible range of RBCs in polycythemia?

6 - 8 million/mm3.

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Blood Loss Anemia

What type of anemia is caused by excessive blood loss?

Blood Loss Anemia.

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Effects of Anemia and Polycythemia on Cardiovascular System

What are common symptoms of anemia?

Fatigue, weakness, pale skin, and shortness of breath.

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Polycythemia

What is primary polycythemia vera characterized by?

An RBC count of 7-8 million/mm3 due to a tumor in the bone marrow.

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Intrinsic and Extrinsic Disorders of RBCs

What is an example of a membrane disorder in RBCs?

Hereditary spherocytosis.

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Blood Loss Anemia

What does normochromic indicate about the RBCs in acute blood loss anemia?

RBCs have normal hemoglobin content.

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Effects of Anemia and Polycythemia on Cardiovascular System

How does cardiac output change in anemia and polycythemia?

Cardiac output is increased in anemia and 3-4 times normal in polycythemia; it remains unchanged.

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Definition of Anemia

What is polycythemia?

A condition where there is an increased number of red blood cells in the bloodstream.

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Blood Loss Anemia

What is a common cause of chronic blood loss anemia?

Chronic bleeding, such as from a peptic ulcer.

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Hemolytic Anemia

What type of anemia is associated with extrinsic disorders of RBCs?

Hemolytic Anemia.

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Effects of Anemia and Polycythemia on Cardiovascular System

What are common symptoms of polycythemia?

Headaches, dizziness, and a ruddy complexion.

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Polycythemia

What is secondary polycythemia characterized by?

An RBC count that may rise to 6-7 million/mm3.

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Hemolytic Anemia

What is thalassemia?

A blood disorder involving less hemoglobin and fewer red blood cells than normal.

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Effects of Anemia and Polycythemia on Cardiovascular System

What happens to cardiac reserve in anemia and polycythemia?

Cardiac reserve is decreased in anemia and remains unchanged in polycythemia.

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Definition of Anemia

What is anemia?

A condition characterized by a deficiency of red blood cells or hemoglobin in the blood.

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Hemolytic Anemia

What are common causes of Hemolytic Anemia?

Autoimmune disorders, infections, certain medications, and inherited conditions.

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Blood Loss Anemia

What type of anemia is characterized by microcytic hypochromic RBCs?

Chronic blood loss anemia.

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Blood Loss Anemia

What does microcytic hypochromic anemia indicate about RBCs?

They are of small size and have little hemoglobin content.

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Aplastic Anemia

How does irradiation contribute to Aplastic Anemia?

It destroys bone marrow.

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Hemolytic Anemia

What is sickle cell anemia?

A genetic disorder that causes red blood cells to become misshapen and break down.

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Blood Viscosity and Flow Dynamics

What is the effect on venous return in anemia and polycythemia?

Venous return is increased in anemia and decreased in polycythemia.

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Effects of Anemia and Polycythemia on Cardiovascular System

How does anemia affect the cardiovascular system?

It can lead to reduced oxygen delivery to tissues, causing fatigue and increased heart rate.

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Hemolytic Anemia

What are the symptoms of Hemolytic Anemia?

Fatigue, pallor, shortness of breath, jaundice, and dark urine.

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Aplastic Anemia

What is Aplastic Anemia?

A condition characterized by the destruction of bone marrow.

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Aplastic Anemia

What is aplastic anemia?

A condition where the bone marrow fails to produce sufficient blood cells.

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Polycythemia

What causes secondary polycythemia?

Hypoxia from conditions like obstructive lung diseases and living at high altitudes.

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Megaloblastic Anemia

What causes Megaloblastic Anemia?

Deficiency of vitamin B12, folic acid, or intrinsic factor from the stomach mucosa.

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Extrinsic Disorders of RBCs

What can cause hemolysis in extrinsic disorders of RBCs?

Bacterial toxins.

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Blood Loss Anemia

What type of anemia is characterized by acute blood loss?

Acute blood loss anemia.

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Hemolytic Anemia

What causes Hemolytic Anemia?

Excessive destruction of RBCs due to abnormalities that make the cells more fragile.

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Blood Loss Anemia

What is a key feature of chronic blood loss anemia?

Chronic loss of iron.

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Blood Loss Anemia

What does normocytic mean in the context of acute blood loss anemia?

RBCs are of normal shape and size.

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Definition of Anemia

What is anemia?

A condition characterized by a deficiency of red blood cells or hemoglobin in the blood.

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Definition of Anemia

What causes anemia?

It can be caused by a decreased number of RBCs or too little hemoglobin in the cells.

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Hemolytic Anemia

How is Hemolytic Anemia diagnosed?

Through blood tests that check for low red blood cell count and signs of hemolysis.

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Intrinsic and Extrinsic Disorders of RBCs

What are intrinsic disorders of RBCs?

Disorders that originate within the red blood cells themselves, affecting their structure or function.

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Intrinsic and Extrinsic Disorders of RBCs

What are hemoglobinopathies?

Disorders related to abnormal hemoglobin, such as sickle cell anemia and thalassemia.

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Blood Viscosity and Flow Dynamics

What happens to peripheral resistance in anemia and polycythemia?

Peripheral resistance is decreased in anemia and increased in polycythemia.

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Extrinsic Disorders of RBCs

What is an example of an antibody causing hemolysis?

Erythroblastosis foetalis or incompatible blood transfusion.

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Effects of Anemia and Polycythemia on Cardiovascular System

What cardiovascular effects can polycythemia cause?

It can increase blood viscosity, leading to higher blood pressure and increased risk of thrombosis.

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Definition of Anemia

What is hemoglobin's role in the blood?

Hemoglobin carries oxygen (O2) in the blood.

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Hemolytic Anemia

What treatments are available for Hemolytic Anemia?

Treatments may include corticosteroids, immunosuppressants, or blood transfusions.

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Blood Loss Anemia

What type of red blood cells (RBCs) are present in acute blood loss anemia?

Normocytic and normochromic.

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Blood Viscosity and Flow Dynamics

How does blood viscosity change in anemia and polycythemia?

In anemia, blood viscosity is decreased; in polycythemia, it is increased.

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Effects of Anemia and Polycythemia on Cardiovascular System

How does blood pressure react in anemia and polycythemia?

In anemia, blood pressure tends to rise due to increased resistance; in polycythemia, it drops when heart failure occurs.

Study Smarter, Not Harder
Study Smarter, Not Harder